B-RAF dissociates from S111/S120 p-SPRY2

Stable Identifier
R-HSA-1295604
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
cytosol
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B-RAF dissociates from S111/S120 p-SPRY2
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MAPK-dependent serine phosphorylation of SPRY2 disrupts complex formation with B-RAF.

Literature References
PubMed ID Title Journal Year
19690147 Sprouty2 association with B-Raf is regulated by phosphorylation and kinase conformation

Brady, SC, Coleman, ML, Munro, J, Feller, SM, Morrice, NA, Olson, MF

Cancer Res 2009
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Authored
Rothfels, K  (2011-08-15)
Reviewed
Gotoh, N  (2011-08-26)
Created
Rothfels, K  (2011-05-18)