p-T184-RASGRP1 [plasma membrane]

Stable Identifier
R-HSA-1169559
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
RASGRP1 phosphorylated at threonine-184, CalDAG-GEFII, RAS guanyl-releasing protein 1, GRP1_HUMAN, RasGRP
Icon
p-T184-RASGRP1 [plasma membrane] icon
p-T184-RASGRP1 [plasma membrane] icon
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
15899849 A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells

Stone, J, Roose, JP, Weiss, A, Gupta, VA, Mollenauer, M

Mol Cell Biol 2005
External Reference Information
External Reference
UniProt:O95267 RASGRP1
Gene Names
RASGRP1, RASGRP
Chain
chain:1-797
Reference Genes
BioGPS Gene:10125 RASGRP1
COSMIC (genes):RASGRP1 RASGRP1
CTD Gene:10125 RASGRP1
dbSNP Gene:10125 RASGRP1
ENSEMBL:ENSG00000172575.14 RASGRP1
HGNC:9878 RASGRP1
KEGG Gene (Homo sapiens):10125 RASGRP1
Monarch:10125 RASGRP1
NCBI Gene:10125 RASGRP1
OMIM:603962 RASGRP1
UCSC:O95267 RASGRP1
Reference Transcript
Other Identifiers
10125
11728920_a_at
11740370_a_at
11747558_a_at
11750397_a_at
11752528_a_at
16807195
205590_PM_at
205590_at
33291_at
3618737
3618738
3618739
3618744
3618745
3618746
3618748
3618749
3618750
3618751
3618752
3618753
3618755
3618757
3618761
3618762
3618763
3618765
3618775
3618777
3618778
3618779
3618780
7987405
A_23_P113258
A_23_P124642
A_32_P195478
GE81550
GO:0000139
GO:0001934
GO:0002376
GO:0002437
GO:0005085
GO:0005509
GO:0005737
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0005886
GO:0006954
GO:0007018
GO:0007155
GO:0007165
GO:0007264
GO:0007265
GO:0008270
GO:0008289
GO:0014066
GO:0016020
GO:0016192
GO:0019992
GO:0023052
GO:0030101
GO:0030154
GO:0031210
GO:0032252
GO:0032725
GO:0032729
GO:0032760
GO:0032816
GO:0032825
GO:0033089
GO:0036211
GO:0042098
GO:0042100
GO:0042110
GO:0042113
GO:0042802
GO:0043226
GO:0043303
GO:0043406
GO:0043547
GO:0045954
GO:0046330
GO:0046579
GO:0046872
GO:0047496
GO:0048856
GO:0050790
GO:0050896
GO:0070372
GO:0070374
GO:0090630
GO:0098542
GO:0098772
HMNXSV003001786
ILMN_1768958
PH_hs_0022905
TC15001217.hg
g6382080_3p_at
Participates
as a member of
Other forms of this molecule
RASGRP1 [cytosol]
Inferred To
Homologues of p-T184-RASGRP1 [plasma membrane] (Dictyostelium discoideum)
phospho-rgef-1 [plasma membrane] (Caenorhabditis elegans)
phospho-p-T184-RASGRP1 [plasma membrane] (Canis familiaris)
phospho-p-T184-RASGRP1 [plasma membrane] (Gallus gallus)
phospho-p-T184-RASGRP1 [plasma membrane] (Mus musculus)
phospho-p-T184-RASGRP1 [plasma membrane] (Rattus norvegicus)
phospho-gefC [plasma membrane] (Dictyostelium discoideum)
phospho-gefM [plasma membrane] (Dictyostelium discoideum)
phospho-gefD [plasma membrane] (Dictyostelium discoideum)
phospho-RASGRP1 [plasma membrane] (Bos taurus)
phospho-RASGRP1 [plasma membrane] (Sus scrofa)
phospho-rasgrp1 [plasma membrane] (Xenopus tropicalis)
phospho-gefN [plasma membrane] (Dictyostelium discoideum)
Modified Residues
Name
O-phospho-L-threonine at 184
Coordinate
184
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ZINC - Substances
ZINC target
PRO
PDB
HPA
GeneCards
Ensembl
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
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