Reactome | phospho-gefV [plasma membrane]

phospho-gefV [plasma membrane]

Stable Identifier

R-DDI-1169559-9

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

plasma membrane

Synonyms

p-T184-RASGRP1, Q55FD8

Locations in the PathwayBrowser

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Immune System (Dictyostelium discoideum)

- Adaptive Immune System (Dictyostelium discoideum)
  - Signaling by the B Cell Receptor (BCR) (Dictyostelium discoideum)
    - Downstream signaling events of B Cell Receptor (BCR) (Dictyostelium discoideum)
      - Activation of RAS in B cells (Dictyostelium discoideum)
        
        p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Dictyostelium discoideum)
        
        p-RASGRP1,3 [plasma membrane] (Dictyostelium discoideum)
        
        Homologues of p-T184-RASGRP1 [plasma membrane] (Dictyostelium discoideum)
        
        phospho-gefV [plasma membrane] (Dictyostelium discoideum)
        
        p-RASGRP1,3:DAG [plasma membrane] (Dictyostelium discoideum)
        
        p-RASGRP1,3 [plasma membrane] (Dictyostelium discoideum)
        
        Homologues of p-T184-RASGRP1 [plasma membrane] (Dictyostelium discoideum)
        
        phospho-gefV [plasma membrane] (Dictyostelium discoideum)

Signal Transduction (Dictyostelium discoideum)

- MAPK family signaling cascades (Dictyostelium discoideum)
  - MAPK1/MAPK3 signaling (Dictyostelium discoideum)
    - RAF/MAP kinase cascade (Dictyostelium discoideum)
      - RAS GEFs promote RAS nucleotide exchange (Dictyostelium discoideum)
        
        RAS GEFs [plasma membrane] (Dictyostelium discoideum)
        
        p-RASGRP1,3:DAG [plasma membrane] (Dictyostelium discoideum)
        
        p-RASGRP1,3 [plasma membrane] (Dictyostelium discoideum)
        
        Homologues of p-T184-RASGRP1 [plasma membrane] (Dictyostelium discoideum)
        
        phospho-gefV [plasma membrane] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q55FD8

Gene Names

gefV

Reference Genes

BioGPS Gene:8616407 gefV

dictyBase:DDB_G0268578

ENSEMBL:DDB_G0268578

KEGG:ddi:DDB_G0268578 gefV

Monarch:8616407 gefV

NCBI Gene:8616407 gefV

UCSC:Q55FD8 gefV

Reference Transcript

RefSeq:XM_642503.1 gefV

Participates

as a member of

Homologues of p-T184-RASGRP1 [plasma membrane] (Dictyostelium discoideum)

Other forms of this molecule

gefV [plasma membrane]

gefV [cytosol]

phospho-gefV [plasma membrane]

gefV [cytosol]

Inferred From

p-T184-RASGRP1 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 184 (in Homo sapiens)

Coordinate

184

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

PRO

Q55FD8

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