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CD36 [platelet alpha granule membrane]
Stable Identifier
R-HSA-114687
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
platelet alpha granule membrane
Synonyms
Platelet glycoprotein IV, GPIV, GPIIIB, CD36 antigen, PAS IV, PAS-4 protein
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Surface deployment of platelet alpha granule membrane components (Homo sapiens)
Platelet alpha granule membrane components that are released on degranulation [platelet alpha granule membrane] (Homo sapiens)
CD36 [platelet alpha granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P16671 CD36
Gene Names
CD36, GP3B, GP4
Chain
initiator methionine:, chain:2-472
Reference Genes
BioGPS Gene:948 CD36
COSMIC (genes):CD36 CD36
CTD Gene:948 CD36
dbSNP Gene:948 CD36
ENSEMBL:ENSG00000135218 CD36
ENSEMBL_homo_sapiens_GENE:ENSG00000135218.19 CD36
HGNC:1663 CD36
KEGG Gene (Homo sapiens):948 CD36
Monarch:948 CD36
NCBI Gene:948 CD36
OMIM:173510 CD36
UCSC:P16671 CD36
Reference Transcript
RefSeq:NM_001289909.1 CD36
RefSeq:NM_001001547.2 CD36
RefSeq:XM_005250715.4 CD36
RefSeq:NM_000072.3 CD36
RefSeq:NM_001289908.1 CD36
RefSeq:XM_005250714.1 CD36
RefSeq:NM_001127444.1 CD36
RefSeq:XM_005250713.1 CD36
RefSeq:NM_001127443.1 CD36
RefSeq:NM_001289911.1 CD36
RefSeq:NM_001001548.2 CD36
Other Identifiers
11724738_a_at
11724875_a_at
11758438_s_at
206488_PM_s_at
206488_s_at
209555_PM_s_at
209555_s_at
228766_PM_at
228766_at
3010504
3010516
3010517
3010524
3010529
3010530
3010531
3010534
3010535
3010542
3010544
3010551
3010552
3010554
3010556
3010559
3010561
3010562
3010564
3010566
3010569
3010570
3010571
3010572
3010577
3010578
3010579
3010580
3010581
3010582
36656_at
49549_at
78617_at
8133876
948
A_14_P120111
A_14_P201955
A_23_P111583
GE58184
GO:0000122
GO:0000165
GO:0001540
GO:0001954
GO:0002376
GO:0002532
GO:0003013
GO:0005041
GO:0005044
GO:0005215
GO:0005324
GO:0005504
GO:0005515
GO:0005576
GO:0005581
GO:0005615
GO:0005737
GO:0005794
GO:0005886
GO:0005901
GO:0006351
GO:0006355
GO:0006629
GO:0006631
GO:0006869
GO:0006886
GO:0006898
GO:0006910
GO:0006911
GO:0006913
GO:0006954
GO:0007155
GO:0007166
GO:0007204
GO:0007263
GO:0007596
GO:0008035
GO:0008289
GO:0009617
GO:0009897
GO:0009986
GO:0010628
GO:0010629
GO:0010744
GO:0010886
GO:0015636
GO:0015909
GO:0015911
GO:0015912
GO:0016020
GO:0016192
GO:0016324
GO:0019915
GO:0019934
GO:0022600
GO:0023052
GO:0030154
GO:0030169
GO:0030194
GO:0030299
GO:0030301
GO:0030666
GO:0031092
GO:0031410
GO:0031526
GO:0031623
GO:0031664
GO:0032731
GO:0032735
GO:0032755
GO:0032760
GO:0033993
GO:0034121
GO:0034197
GO:0034381
GO:0034383
GO:0034599
GO:0035325
GO:0035579
GO:0035634
GO:0036211
GO:0038024
GO:0042060
GO:0042308
GO:0042953
GO:0043123
GO:0043226
GO:0043235
GO:0043254
GO:0043277
GO:0043410
GO:0044539
GO:0044877
GO:0045121
GO:0045177
GO:0045335
GO:0045429
GO:0048856
GO:0050431
GO:0050731
GO:0050830
GO:0050877
GO:0050892
GO:0050909
GO:0051092
GO:0055085
GO:0055096
GO:0060089
GO:0060100
GO:0060907
GO:0061024
GO:0065003
GO:0070053
GO:0070374
GO:0070508
GO:0070542
GO:0070543
GO:0070892
GO:0071221
GO:0071222
GO:0071223
GO:0071404
GO:0071447
GO:0071726
GO:0071813
GO:0071944
GO:0097009
GO:0098542
GO:0098754
GO:0098900
GO:0120162
GO:0140052
GO:0150024
GO:0150025
GO:0150094
GO:1900227
GO:1901480
GO:1903428
GO:1904646
GO:1990000
GO:1990379
GO:2000121
GO:2000334
GO:2000379
HMNXSV003044379
Hs.325823.0.A1_3p_at
ILMN_1665132
ILMN_1784863
ILMN_1796094
M98399_s_at
PH_hs_0036027
Z32765_at
g180112_3p_a_at
g4557418_3p_at
Participates
as a member of
Platelet alpha granule membrane components that are released on degranulation [platelet alpha granule membrane] (Homo sapiens)
Other forms of this molecule
4xPalmC-CD36 [specific granule membrane]
CD36 [phagocytic vesicle]
4xPalmC-CD36 [endocytic vesicle membrane]
4xPalmC-CD36 [plasma membrane]
Inferred To
scav-4 [platelet alpha granule membrane]
(Caenorhabditis elegans)
Snmp1 [platelet alpha granule membrane]
(Drosophila melanogaster)
Cd36 [platelet alpha granule membrane]
(Mus musculus)
Cd36 [platelet alpha granule membrane]
(Rattus norvegicus)
lmpC [platelet alpha granule membrane]
(Dictyostelium discoideum)
scav-6 [platelet alpha granule membrane]
(Caenorhabditis elegans)
CD36 [platelet alpha granule membrane]
(Bos taurus)
CD36 [platelet alpha granule membrane]
(Caenorhabditis elegans)
CD36 [platelet alpha granule membrane]
(Canis familiaris)
CD36 [platelet alpha granule membrane]
(Gallus gallus)
CD36 [platelet alpha granule membrane]
(Sus scrofa)
scav-2 [platelet alpha granule membrane]
(Caenorhabditis elegans)
lmpB [platelet alpha granule membrane]
(Dictyostelium discoideum)
Homologues of CD36 [platelet alpha granule membrane]
(Caenorhabditis elegans)
Homologues of CD36 [platelet alpha granule membrane]
(Dictyostelium discoideum)
Homologues of CD36 [platelet alpha granule membrane]
(Drosophila melanogaster)
scav-3 [platelet alpha granule membrane]
(Caenorhabditis elegans)
Snmp2 [platelet alpha granule membrane]
(Drosophila melanogaster)
cd36 [platelet alpha granule membrane]
(Danio rerio)
cd36 [platelet alpha granule membrane]
(Xenopus tropicalis)
lmpA [platelet alpha granule membrane]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_000063.2
,
NP_001120915.1
,
XP_005250770.1
,
NP_001001548.1
,
NP_001276837.1
,
NP_001120916.1
,
XP_005250771.1
,
NP_001276840.1
,
NP_001001547.1
,
NP_001276838.1
,
XP_005250772.1
Guide to Pharmacology - Targets
3104
OpenTargets
ENSG00000135218
ZINC target
P16671
PRO
P16671
PDB
5LGD
HPA
ENSG00000135218-CD36
GeneCards
P16671
Ensembl
ENSG00000135218
,
ENST00000538969
,
ENSP00000439543
,
ENSP00000415743
,
ENST00000433696
,
ENST00000435819
,
ENST00000432207
,
ENSP00000308165
,
ENSP00000378268
,
ENSP00000401863
,
ENST00000447544
,
ENST00000394788
,
ENSP00000399421
,
ENST00000309881
,
ENSP00000411411
,
ENSP00000441956
,
ENST00000544133
Pharos - Targets
P16671
Orphanet
25596
ZINC - Predictions - Purchasable
CD36_HUMAN
HMDB Protein
HMDBP02136
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P07996-PRO_0000035842 THBS1
0.558
2
UniProt:P13051-2 UNG
0.556
3
UniProt:P05067 APP
20
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.556
3
UniProt:Q9UKG9 CROT
2
CROT [cytosol]
(R-HSA-9033106)
CROT [peroxisomal matrix]
(R-HSA-390296)
0.527
2
UniProt:P07948 LYN
7
MyrG2-PalmC3-LYN [lysosomal membrane]
(R-HSA-9707903)
MyrG2-PalmC3-LYN [endocytic vesicle membrane]
(R-HSA-9705728)
LYN [plasma membrane]
(R-HSA-197943)
p-Y397-LYN [cytosol]
(R-HSA-8942608)
p-Y397-LYN [plasma membrane]
(R-HSA-2454229)
MyrG2-PalmC3-LYN [plasma membrane]
(R-HSA-9606875)
LYN [cytosol]
(R-HSA-354251)
0.499
3
UniProt:P49023 PXN
4
p-Y-PXN [plasma membrane]
(R-HSA-9031680)
PXN [plasma membrane]
(R-HSA-180493)
PXN [cytosol]
(R-HSA-210014)
p-Y31,Y118-PXN [cytosol]
(R-HSA-5218693)
0.462
2
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