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ITGA2B(32-?) [platelet alpha granule membrane]
Stable Identifier
R-HSA-114511
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
platelet alpha granule membrane
Synonyms
Integrin alpha-IIb, Platelet membrane glycoprotein IIb, GPalpha IIb, GPIIb, CD41 antigen
Icon
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Surface deployment of platelet alpha granule membrane components (Homo sapiens)
Platelet alpha granule membrane components that are released on degranulation [platelet alpha granule membrane] (Homo sapiens)
Alpha IIb Beta 3 Integrin [platelet alpha granule membrane] (Homo sapiens)
ITGA2B(32-?) [platelet alpha granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P08514 ITGA2B
Gene Names
ITGA2B, GP2B, ITGAB
Chain
signal peptide:1-31, chain:32-1039, chain:32-887, chain:891-1039, chain:903-1039
Reference Genes
COSMIC (genes):ITGA2B ITGA2B
dbSNP Gene:3674 ITGA2B
ENSEMBL:ENSG00000005961 ITGA2B
Participates
as a component of
Alpha IIb Beta 3 Integrin [platelet alpha granule membrane] (Homo sapiens)
Other forms of this molecule
ITGA2B(32-1039) [plasma membrane]
Inferred To
itga2b.1 [platelet alpha granule membrane]
(Xenopus tropicalis)
ITGA2B [platelet alpha granule membrane]
(Bos taurus)
ITGA2B [platelet alpha granule membrane]
(Canis familiaris)
ITGA2B [platelet alpha granule membrane]
(Sus scrofa)
pat-2 [platelet alpha granule membrane]
(Caenorhabditis elegans)
itga2b [platelet alpha granule membrane]
(Danio rerio)
ITGA2B(32-?) [platelet alpha granule membrane]
(Gallus gallus)
ITGA2B(32-?) [platelet alpha granule membrane]
(Mus musculus)
if [platelet alpha granule membrane]
(Drosophila melanogaster)
Itga2b [platelet alpha granule membrane]
(Rattus norvegicus)
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P05106 ITGB3
3
ITGB3 [plasma membrane]
(R-HSA-57600)
ITGB3(27-?) [platelet alpha granule membrane]
(R-HSA-114512)
p-T779-ITGB3 [plasma membrane]
(R-HSA-432107)
0.815
12
UniProt:P08514 ITGA2B
2
ITGA2B(32-?) [platelet alpha granule membrane]
(R-HSA-114511)
ITGA2B(32-1039) [plasma membrane]
(R-HSA-57578)
0.795
7
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