MPG glycosylase mediated recognition and binding of 3-methyladenine

Stable Identifier
R-HSA-110238
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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MPG glycosylase mediated recognition and binding of 3-methyladenine
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MPG, a 3-methyladenine DNA glycosylase, recognizes alkylation damage of DNA in the form of 3-methyladenine (Samson et al. 1991, Vickers et al. 1993, O'Connor 1993, Lau et al. 1998).
Literature References
PubMed ID Title Journal Year
8475094 Structure of the human 3-methyladenine DNA glycosylase gene and localization close to the 16p telomere

Vickers, MA, Vyas, P, Harris, PC, Simmons, DL, Higgs, DR

Proc. Natl. Acad. Sci. U.S.A. 1993
8284199 Purification and characterization of human 3-methyladenine-DNA glycosylase

O'Connor, TR

Nucleic Acids Res. 1993
1924375 Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16

Samson, L, Derfler, B, Boosalis, M, Call, K

Proc. Natl. Acad. Sci. U.S.A. 1991
9790531 Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision

Lau, AY, Schärer, OD, Samson, L, Verdine, GL, Ellenberger, T

Cell 1998
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as an event of
Authored
Matthews, L  (2004-02-03)
Reviewed
Borowiec, JA  (2014-12-22)
Created
Matthews, L  (2004-01-29)
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