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(8oxoG:Cyt)-dsDNA [nucleoplasm]
Stable Identifier
R-HSA-110184
Type
Genes and Transcripts [GenomeEncodedEntity]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Double-strand DNA containing an 8-oxo guanine opposite to a cytosine
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
Base Excision Repair (Homo sapiens)
Base-Excision Repair, AP Site Formation (Homo sapiens)
Depurination (Homo sapiens)
Cleavage of the damaged purine (Homo sapiens)
Excision of 8-oxoguanine by OGG1 glycosylase (Homo sapiens)
OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
(8oxoG:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
Recognition and association of DNA glycosylase with site containing an affected purine (Homo sapiens)
OGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine (Homo sapiens)
(8oxoG:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
(8oxoG:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Diseases of DNA repair (Homo sapiens)
Diseases of Base Excision Repair (Homo sapiens)
Defective Base Excision Repair Associated with OGG1 (Homo sapiens)
Defective OGG1 Substrate Binding (Homo sapiens)
Defective OGG1 mutants show decreased binding to 8-oxoguanine (Homo sapiens)
(8oxoG:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
Defective OGG1 Substrate Processing (Homo sapiens)
Defective OGG1 mutants do not excise 8-oxoguanine (Homo sapiens)
OGG1 mutants:(8oxoG:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
(8oxoG:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
Participates
as an input of
Defective OGG1 mutants show decreased binding to 8-oxoguanine (Homo sapiens)
OGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine (Homo sapiens)
as a component of
OGG1 mutants:(8oxoG:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
Inferred To
Ghost homologue of (8oxoG:Cyt)-dsDNA [nucleoplasm]
(Bos taurus)
Ghost homologue of (8oxoG:Cyt)-dsDNA [nucleoplasm]
(Canis familiaris)
Ghost homologue of (8oxoG:Cyt)-dsDNA [nucleoplasm]
(Dictyostelium discoideum)
Ghost homologue of (8oxoG:Cyt)-dsDNA [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of (8oxoG:Cyt)-dsDNA [nucleoplasm]
(Mus musculus)
Ghost homologue of (8oxoG:Cyt)-dsDNA [nucleoplasm]
(Plasmodium falciparum)
Ghost homologue of (8oxoG:Cyt)-dsDNA [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of (8oxoG:Cyt)-dsDNA [nucleoplasm]
(Saccharomyces cerevisiae)
Cross References
ChEBI
16991
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