MAPK3 (ERK1) activation

Stable Identifier
R-HSA-110056
Type
Pathway
Species
Homo sapiens
Compartment
cytosol, nucleoplasm
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MAPK3 (ERK1) activation
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Mitogen-activated protein kinase kinase MAP2K1 (also known as MEK1) is a dual threonine and tyrosine recognition kinase that phosphorylates and activates MAPK3 (ERK1) (Ohren et al. 2004; Roskoski 2012a).

Participants
Events
Participant Of
hasEvent
Event Information
Go Biological Process
ERK1 and ERK2 cascade (0070371)
Orthologous Events
MAPK3 (ERK1) activation (Caenorhabditis elegans)
MAPK3 (ERK1) activation (Canis familiaris)
MAPK3 (ERK1) activation (Danio rerio)
MAPK3 (ERK1) activation (Drosophila melanogaster)
MAPK3 (ERK1) activation (Gallus gallus)
MAPK3 (ERK1) activation (Mus musculus)
MAPK3 (ERK1) activation (Rattus norvegicus)
MAPK3 (ERK1) activation (Saccharomyces cerevisiae)
MAPK3 (ERK1) activation (Schizosaccharomyces pombe)
MAPK3 (ERK1) activation (Xenopus tropicalis)
Cross References
BioModels Database
Authored
Charalambous, M  (2005-02-04)
Reviewed
Greene, LA  (2007-11-08)
Created
Charalambous, M  (2004-04-29)
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