Dissociation of p-T,Y-MAPK3:MAP2K1

Stable Identifier
R-HSA-109863
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Dissociation of p-T,Y-MAPK3:MAP2K1
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MAP2K1 (MEK1) dissociates from phosphorylated MAPK3 (ERK1), allowing the dimerization of p-S202,204-MAP2K.
Literature References
PubMed ID Title Journal Year
19219045 A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal

Catalanotti, F, Reyes, G, Jesenberger, V, Galabova-Kovacs, G, de Matos Simoes, R, Carugo, O, Baccarini, M

Nat. Struct. Mol. Biol. 2009
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Orthologous Events
Dissociation of p-T,Y-MAPK3:MAP2K1 (Bos taurus)
Dissociation of p-T,Y-MAPK3:MAP2K1 (Caenorhabditis elegans)
Dissociation of p-T,Y-MAPK3:MAP2K1 (Danio rerio)
Dissociation of p-T,Y-MAPK3:MAP2K1 (Dictyostelium discoideum)
Dissociation of p-T,Y-MAPK3:MAP2K1 (Drosophila melanogaster)
Dissociation of p-T,Y-MAPK3:MAP2K1 (Mus musculus)
Dissociation of p-T,Y-MAPK3:MAP2K1 (Rattus norvegicus)
Authored
Charalambous, M  (2005-02-04)
Reviewed
Gillespie, ME  (2010-11-24)
Created
Charalambous, M  (2004-04-29)
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