IL6 binds IL6R

Stable Identifier
R-HSA-1067667
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Synonyms
Interleukin-6 binds to IL-6 receptor alpha subunit
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Interleukin-6 (IL6) site I interacts with Interleukin-6 receptor subunit alpha (IL6R), which is non-signaling but ligand specific.

Literature References
PubMed ID Title Journal Year
2788034 Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

Taga, T, Hibi, M, Hirata, Y, Yamasaki, K, Yasukawa, K, Matsuda, T, Hirano, T, Kishimoto, T

Cell 1989
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created