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K63polyUb-CFLAR(1-480) [cytosol]
Stable Identifier
R-GGA-9818805
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
F1NL59
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Gallus gallus)
Apoptosis (Gallus gallus)
Caspase activation via extrinsic apoptotic signalling pathway (Gallus gallus)
Caspase activation via Death Receptors in the presence of ligand (Gallus gallus)
Regulation by c-FLIP (Gallus gallus)
FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Gallus gallus)
K63polyUb-CFLAR(1-480) [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Death Receptor Signaling (Gallus gallus)
TNF signaling (Gallus gallus)
Regulation of TNFR1 signaling (Gallus gallus)
FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Gallus gallus)
K63polyUb-CFLAR(1-480) [cytosol] (Gallus gallus)
MIB2 ubiquitinates CFLAR (Gallus gallus)
K63polyUb-CFLAR(1-480) [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:F1NL59
Reference Genes
ENSEMBL:ENSGALG00000001366
Participates
as an output of
MIB2 ubiquitinates CFLAR (Gallus gallus)
This entity regulates
Negatively
FLIP(L) and procaspase-8 form heterodimer in TNF signaling
(Gallus gallus)
Other forms of this molecule
CFLAR(377-480) [cytosol]
phospho-p-S196-CASP9(1-416) [cytosol]
phospho-p-T412-CASP9(1-416) [cytosol]
CASP9(331-416) [cytosol]
CASP9(?-315) [cytosol]
CFLAR(1-376) [cytosol]
CFLAR(1-480) [cytosol]
FLIP(S) [cytosol]
CASP9(1-416) [cytosol]
Inferred From
K63polyUb-CFLAR(1-480) [cytosol]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (K63polyUb [cytosol]) at 460 (in Homo sapiens)
Coordinate
460
Modification
K63polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Name
ubiquitinylated lysine (K63polyUb [cytosol]) at 462 (in Homo sapiens)
Coordinate
462
Modification
K63polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Name
ubiquitinylated lysine (K63polyUb [cytosol]) at 473 (in Homo sapiens)
Coordinate
473
Modification
K63polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Name
ubiquitinylated lysine (K63polyUb [cytosol]) at 474 (in Homo sapiens)
Coordinate
474
Modification
K63polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
PRO
F1NL59
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