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FLIP(S) [cytosol]
Stable Identifier
R-GGA-3465357
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
F1NL59
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Gallus gallus)
Apoptosis (Gallus gallus)
Caspase activation via extrinsic apoptotic signalling pathway (Gallus gallus)
Caspase activation via Death Receptors in the presence of ligand (Gallus gallus)
Dimerization of procaspase-8 (Gallus gallus)
FAS-mediated dimerization of procaspase-8 (Gallus gallus)
FLIP(S) [cytosol] (Gallus gallus)
TNF-mediated dimerization of procaspase-8 (Gallus gallus)
FLIP(S) [cytosol] (Gallus gallus)
TRAIL-mediated dimerization of procaspase-8 (Gallus gallus)
FLIP(S) [cytosol] (Gallus gallus)
Regulated Necrosis (Gallus gallus)
RIPK1-mediated regulated necrosis (Gallus gallus)
Regulation of necroptotic cell death (Gallus gallus)
CASP8 activity is inhibited (Gallus gallus)
FLIP(S) and procaspase-8 form heterodimer (Gallus gallus)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Gallus gallus)
FLIP(S) [cytosol] (Gallus gallus)
FLIP(S) [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:F1NL59
Reference Genes
ENSEMBL:ENSGALG00000001366
Participates
as an input of
FLIP(S) and procaspase-8 form heterodimer (Gallus gallus)
as a component of
DISC:procaspase-8:FLIP(S) [plasma membrane] (Gallus gallus)
This entity regulates
Negatively
FAS-mediated dimerization of procaspase-8
(Gallus gallus)
TRAIL-mediated dimerization of procaspase-8
(Gallus gallus)
TNF-mediated dimerization of procaspase-8
(Gallus gallus)
Other forms of this molecule
CFLAR(377-480) [cytosol]
K63polyUb-CFLAR(1-480) [cytosol]
phospho-p-S196-CASP9(1-416) [cytosol]
phospho-p-T412-CASP9(1-416) [cytosol]
CASP9(331-416) [cytosol]
CASP9(?-315) [cytosol]
CFLAR(1-376) [cytosol]
CFLAR(1-480) [cytosol]
CASP9(1-416) [cytosol]
Inferred From
FLIP(S) [cytosol]
(Homo sapiens)
Cross References
PRO
F1NL59
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