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EGF-like ligands [extracellular region]
Stable Identifier
R-DRE-9624194
Type
Set [DefinedSet]
Species
Danio rerio
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Signal Transduction (Danio rerio)
Intracellular signaling by second messengers (Danio rerio)
PIP3 activates AKT signaling (Danio rerio)
Negative regulation of the PI3K/AKT network (Danio rerio)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK1/MAPK3 signaling (Danio rerio)
RAF/MAP kinase cascade (Danio rerio)
RAS GEFs promote RAS nucleotide exchange (Danio rerio)
RAS GEFs [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by EGFR (Danio rerio)
EGFR autophosphorylation (Danio rerio)
EGF-like ligands:EGFR dimer [plasma membrane] (Danio rerio)
EGFR:EGF-like ligands [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGFR binds EGF ligand (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGFR:EGF-like ligands [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGFR dimerization (Danio rerio)
EGF-like ligands:EGFR dimer [plasma membrane] (Danio rerio)
EGFR:EGF-like ligands [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGFR:EGF-like ligands [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGFR downregulation (Danio rerio)
Binding of CBL to EGFR (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
CBL binds and ubiquitinates phosphorylated Sprouty (Danio rerio)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
CBL ubiquitinates Sprouty (Danio rerio)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:CBL:p-Y53/55-SPRY1/2 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
Localization of CBL:GRB2 to the membrane (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
Phosphorylation of CBL (EGFR:CBL) (Danio rerio)
EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Danio rerio)
EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
Ubiquitination of stimulated EGFR (CBL) (Danio rerio)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
Ubiquitination of stimulated EGFR (CBL:GRB2) (Danio rerio)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGFR interacts with phospholipase C-gamma (Danio rerio)
Active PLC-gamma1 dissociates from EGFR (Danio rerio)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGFR activates PLC-gamma1 by phosphorylation (Danio rerio)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
Phospholipase C-gamma1 binds to the activated EGF receptor (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
GAB1 signalosome (Danio rerio)
GAB1 phosphorylation by EGFR kinase (Danio rerio)
EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
PI3K binds to EGF:EGFR:GRB2:GAB1 (Danio rerio)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Danio rerio)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
GRB2 events in EGFR signaling (Danio rerio)
GRB2:SOS1 complex binds to EGF:EGFR complex (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Danio rerio)
EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
Phosphorylation of EGFR by SRC kinase (Danio rerio)
EGF-like ligands:EGFR dimer [plasma membrane] (Danio rerio)
EGFR:EGF-like ligands [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
SHC1 events in EGFR signaling (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Danio rerio)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
EGF-like ligands [extracellular region] (Danio rerio)
Participants
members
areg [extracellular region]
(Danio rerio)
hbegfa [extracellular region]
(Danio rerio)
epgn [extracellular region]
(Danio rerio)
btc [extracellular region]
(Danio rerio)
Participates
as a component of
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Danio rerio)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Danio rerio)
EGFR:EGF-like ligands [plasma membrane] (Danio rerio)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
as an input of
EGFR binds EGF ligand (Danio rerio)
Inferred From
EGF-like ligands [extracellular region]
(Homo sapiens)
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