Reactome | BTC(32-111) [extracellular region]

BTC(32-111) [extracellular region]

Stable Identifier

R-DRE-1233224

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

extracellular region

Synonyms

A0A0R4INZ6

Locations in the PathwayBrowser

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Signal Transduction (Danio rerio)

- Intracellular signaling by second messengers (Danio rerio)
  - PIP3 activates AKT signaling (Danio rerio)
    - Negative regulation of the PI3K/AKT network (Danio rerio)
      - PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Danio rerio)
        
        PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
        
        Activator:PI3K [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        PI3K:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        p-ERBB4cyt1 homodimers [plasma membrane] (Danio rerio)
        
        p-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
      - Activator:PI3K [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        PI3K:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        p-ERBB4cyt1 homodimers [plasma membrane] (Danio rerio)
        
        p-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
- MAPK family signaling cascades (Danio rerio)
  - MAPK1/MAPK3 signaling (Danio rerio)
    - RAF/MAP kinase cascade (Danio rerio)
      - RAS GEFs promote RAS nucleotide exchange (Danio rerio)
        
        RAS GEFs [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        GRB2:SOS1:p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        GRB2:SOS1:p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Danio rerio)
        
        p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Danio rerio)
        
        p-ERBB4 homodimers [plasma membrane] (Danio rerio)
        
        p-ERBB4cyt1 homodimers [plasma membrane] (Danio rerio)
        
        p-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB4jmAcyt2 homodimer [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-ERBB2:GRB2:SOS1 [plasma membrane] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4 heterodimers [plasma membrane] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4cyt2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
- Signaling by Non-Receptor Tyrosine Kinases (Danio rerio)
  - Signaling by PTK6 (Danio rerio)
    - ERBB2 Activates PTK6 Signaling (Danio rerio)
      - Activated ERBB2 binds PTK6 (BRK) (Danio rerio)
        
        p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB2 heterodimers:PTK6 [plasma membrane] (Danio rerio)
        
        p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - ERBB2 promotes PTK6 autophosphorylation (Danio rerio)
        
        p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB2 heterodimers:PTK6 [plasma membrane] (Danio rerio)
        
        p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
- Signaling by Receptor Tyrosine Kinases (Danio rerio)
  - Signaling by EGFR (Danio rerio)
    - EGFR autophosphorylation (Danio rerio)
      - EGF-like ligands:EGFR dimer [plasma membrane] (Danio rerio)
        
        EGFR:EGF-like ligands [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - EGFR binds EGF ligand (Danio rerio)
      - EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - EGFR:EGF-like ligands [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - EGFR dimerization (Danio rerio)
      - EGF-like ligands:EGFR dimer [plasma membrane] (Danio rerio)
        
        EGFR:EGF-like ligands [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - EGFR:EGF-like ligands [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - EGFR downregulation (Danio rerio)
      - Binding of CBL to EGFR (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - CBL binds and ubiquitinates phosphorylated Sprouty (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - CBL ubiquitinates Sprouty (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:CBL:p-Y53/55-SPRY1/2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - Localization of CBL:GRB2 to the membrane (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - Phosphorylation of CBL (EGFR:CBL) (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - Phosphorylation of CBL (EGFR:GRB2:CBL) (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - Ubiquitination of stimulated EGFR (CBL) (Danio rerio)
        
        EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - Ubiquitination of stimulated EGFR (CBL:GRB2) (Danio rerio)
        
        EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - EGFR interacts with phospholipase C-gamma (Danio rerio)
      - Active PLC-gamma1 dissociates from EGFR (Danio rerio)
        
        EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - EGFR activates PLC-gamma1 by phosphorylation (Danio rerio)
        
        EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - Phospholipase C-gamma1 binds to the activated EGF receptor (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - GAB1 signalosome (Danio rerio)
      - GAB1 phosphorylation by EGFR kinase (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - PI3K binds to EGF:EGFR:GRB2:GAB1 (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - GRB2 events in EGFR signaling (Danio rerio)
      - GRB2:SOS1 complex binds to EGF:EGFR complex (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - Phosphorylation of EGFR by SRC kinase (Danio rerio)
      - EGF-like ligands:EGFR dimer [plasma membrane] (Danio rerio)
        
        EGFR:EGF-like ligands [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - SHC1 events in EGFR signaling (Danio rerio)
      - SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
  - Signaling by ERBB2 (Danio rerio)
    - Downregulation of ERBB2 signaling (Danio rerio)
      - PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 (Danio rerio)
        
        Heterodimers of p-ERBB2 dephosphorylated at Y1248 [plasma membrane] (Danio rerio)
        
        Phosphorylated p-Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        Phosphorylated p-Y877,Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-Y877,Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-Y877,Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-Y877,Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - ERBB2 Activates PTK6 Signaling (Danio rerio)
      - Activated ERBB2 binds PTK6 (BRK) (Danio rerio)
        
        p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB2 heterodimers:PTK6 [plasma membrane] (Danio rerio)
        
        p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - ERBB2 promotes PTK6 autophosphorylation (Danio rerio)
        
        p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB2 heterodimers:PTK6 [plasma membrane] (Danio rerio)
        
        p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - ERBB2 Regulates Cell Motility (Danio rerio)
      - Phosphorylated ERBB2 heterodimers bind MEMO1 (Danio rerio)
        
        p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB2 heterodimers:MEMO1 [plasma membrane] (Danio rerio)
        
        p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - GRB2 events in ERBB2 signaling (Danio rerio)
      - GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-ERBB2:GRB2:SOS1 [plasma membrane] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4 heterodimers [plasma membrane] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4cyt2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4 heterodimers [plasma membrane] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4cyt2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-ERBB2:GRB2:SOS1 [plasma membrane] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4 heterodimers [plasma membrane] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4cyt2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - PI3K events in ERBB2 signaling (Danio rerio)
      - Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane] (Danio rerio)
        
        Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - SHC1 events in ERBB2 signaling (Danio rerio)
      - SHC1 phosphorylation by ERBB2 heterodimers (Danio rerio)
        
        SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        p-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - SRC family kinases phosphorylate ERBB2 (Danio rerio)
      - ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:ERBB4:ERBB2 [plasma membrane] (Danio rerio)
        
        ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        ERBB2:ERBB4cyt2 heterodimer [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:ERBB4:p-Y877-ERBB2 [plasma membrane] (Danio rerio)
        
        p-Y877-ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-Y877-ERBB2:ERBB4cyt2 heterodimer [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - Trans-autophosphorylation of ERBB2 heterodimers (Danio rerio)
      - ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:ERBB4:ERBB2 [plasma membrane] (Danio rerio)
        
        ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        ERBB2:ERBB4cyt2 heterodimer [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - p-6Y-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-6Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Danio rerio)
      - Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt1:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGFLs:p-ERBB4cyt2:p-7Y-ERBB2 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - p-Y877-ERBB2 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGFLs:ERBB4:p-Y877-ERBB2 [plasma membrane] (Danio rerio)
        
        p-Y877-ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-Y877-ERBB2:ERBB4cyt2 heterodimer [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
  - Signaling by ERBB4 (Danio rerio)
    - ERBB4 binds NRGs or EGF-like ligands (Danio rerio)
      - EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - NRGs/EGF-like ligands:ERBB4 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - ERBB4 forms heterodimers with ERBB3 (Danio rerio)
      - ERBB4:ERBB3 heterodimer [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - NRGs/EGF-like ligands:ERBB4 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - Homodimerization of ERBB4 (Danio rerio)
      - ERBB4 homodimers [plasma membrane] (Danio rerio)
        
        ERBB4cyt1 homodimers [plasma membrane] (Danio rerio)
        
        ERBB4jmAcyt1 homodimer [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        ERBB4jmBcyt1 homodimer [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        ERBB4jmAcyt2 homodimer [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - NRGs/EGF-like ligands:ERBB4 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - PI3K events in ERBB4 signaling (Danio rerio)
      - Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers (Danio rerio)
        
        PI3K:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        p-ERBB4cyt1 homodimers [plasma membrane] (Danio rerio)
        
        p-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB4cyt1 homodimers [plasma membrane] (Danio rerio)
        
        p-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Danio rerio)
        
        PI3K:p-ERBB4cyt1 [plasma membrane] (Danio rerio)
        
        p-ERBB4cyt1 homodimers [plasma membrane] (Danio rerio)
        
        p-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - SHC1 events in ERBB4 signaling (Danio rerio)
      - RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Danio rerio)
        
        GRB2:SOS1:p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Danio rerio)
        
        p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Danio rerio)
        
        p-ERBB4 homodimers [plasma membrane] (Danio rerio)
        
        p-ERBB4cyt1 homodimers [plasma membrane] (Danio rerio)
        
        p-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB4jmAcyt2 homodimer [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
    - Trans-autophosphorylation of ERBB4 homodimers (Danio rerio)
      - ERBB4 homodimers [plasma membrane] (Danio rerio)
        
        ERBB4cyt1 homodimers [plasma membrane] (Danio rerio)
        
        ERBB4jmAcyt1 homodimer [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        ERBB4jmBcyt1 homodimer [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        ERBB4jmAcyt2 homodimer [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:ERBB4jmAcyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
      - p-ERBB4 homodimers [plasma membrane] (Danio rerio)
        
        p-ERBB4cyt1 homodimers [plasma membrane] (Danio rerio)
        
        p-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:P-ERBB4jmBcyt1 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)
        
        p-ERBB4jmAcyt2 homodimer [plasma membrane] (Danio rerio)
        
        NRGs/EGF-like ligands:p-ERBB4cyt2 [plasma membrane] (Danio rerio)
        
        EGF-like ligands [extracellular region] (Danio rerio)
        
        BTC(32-111) [extracellular region] (Danio rerio)

External Reference Information

External Reference

UniProt:A0A0R4INZ6

Reference Genes

BioGPS Gene:503869

ENSEMBL:ENSDARG00000098112

ENSEMBL:ENSDARG00000098112.2

ENSEMBL:ENSDARG00000110368.1

Monarch:503869

NCBI Gene:503869

Reference Transcript

RefSeq:XM_005161175.3

Other Identifiers

13109410

13300222

503869

A_15_P161071

A_15_P238151

BC124289

CUST_8497_PI428451958

CUST_8571_PI428451953

CUST_8573_PI428451953

DRER14267

ENSDART00000093153

ENSDART00000093153_1

ENSDART00000093153_2

ENSDART00000101482

ENSDART00000101482_y_1

ENSDART00000112089

ENSDART00000114031

GO:0000278

GO:0005154

GO:0005576

GO:0005615

GO:0007173

GO:0008083

GO:0008284

GO:0016020

GO:0023052

GO:0045840

GO:0048018

GO:0048856

GO:0098772

GO:0140014

GT_Xhyb_NM_001044764.2_113126

GT_Xhyb_XM_005161175.1_294335

MADDr01006003

NM_001044764

XM_686509

Participates

as a member of

Inferred From

BTC(32-111) [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_005161232.1

ZFIN

ZDB-GENE-050311-1

Ensembl

ENSDARP00000145704, ENSDARP00000137815, ENSDARG00000098112, ENSDART00000184530, ENSDARP00000150018, ENSDART00000187759, ENSDARP00000136928, ENSDART00000168728, ENSDART00000158471, ENSDARP00000157166, ENSDART00000185829, ENSDARG00000110368

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