Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
20S CP outer ring [nucleoplasm]
Stable Identifier
R-DME-9918351
Type
Complex
Species
Drosophila melanogaster
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle Checkpoints (Drosophila melanogaster)
G1/S DNA Damage Checkpoints (Drosophila melanogaster)
p53-Independent G1/S DNA Damage Checkpoint (Drosophila melanogaster)
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A (Drosophila melanogaster)
Proteolytic degradation of ubiquitinated-Cdc25A (Drosophila melanogaster)
26S proteasome [nucleoplasm] (Drosophila melanogaster)
20S core particle [nucleoplasm] (Drosophila melanogaster)
20S CP outer ring [nucleoplasm] (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
Mitotic G1 phase and G1/S transition (Drosophila melanogaster)
G1/S Transition (Drosophila melanogaster)
Cyclin E associated events during G1/S transition (Drosophila melanogaster)
SCF(Skp2)-mediated degradation of p27/p21 (Drosophila melanogaster)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Drosophila melanogaster)
26S proteasome [nucleoplasm] (Drosophila melanogaster)
20S core particle [nucleoplasm] (Drosophila melanogaster)
20S CP outer ring [nucleoplasm] (Drosophila melanogaster)
Regulation of mitotic cell cycle (Drosophila melanogaster)
APC/C-mediated degradation of cell cycle proteins (Drosophila melanogaster)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Drosophila melanogaster)
APC/C:Cdh1-mediated degradation of Skp2 (Drosophila melanogaster)
26S proteasome [nucleoplasm] (Drosophila melanogaster)
20S core particle [nucleoplasm] (Drosophila melanogaster)
20S CP outer ring [nucleoplasm] (Drosophila melanogaster)
Autodegradation of Cdh1 by Cdh1:APC/C (Drosophila melanogaster)
Degradation of multiubiquitinated Cdh1 (Drosophila melanogaster)
26S proteasome [nucleoplasm] (Drosophila melanogaster)
20S core particle [nucleoplasm] (Drosophila melanogaster)
20S CP outer ring [nucleoplasm] (Drosophila melanogaster)
S Phase (Drosophila melanogaster)
Cyclin A:Cdk2-associated events at S phase entry (Drosophila melanogaster)
SCF(Skp2)-mediated degradation of p27/p21 (Drosophila melanogaster)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Drosophila melanogaster)
26S proteasome [nucleoplasm] (Drosophila melanogaster)
20S core particle [nucleoplasm] (Drosophila melanogaster)
20S CP outer ring [nucleoplasm] (Drosophila melanogaster)
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to chemical stress (Drosophila melanogaster)
KEAP1-NFE2L2 pathway (Drosophila melanogaster)
Nuclear events mediated by NFE2L2 (Drosophila melanogaster)
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 (Drosophila melanogaster)
Ub,pS335,S338,T NFE2L2 is degraded (Drosophila melanogaster)
26S proteasome [nucleoplasm] (Drosophila melanogaster)
20S core particle [nucleoplasm] (Drosophila melanogaster)
20S CP outer ring [nucleoplasm] (Drosophila melanogaster)
DNA Replication (Drosophila melanogaster)
DNA Replication Pre-Initiation (Drosophila melanogaster)
Assembly of the pre-replicative complex (Drosophila melanogaster)
Ubiquitinated geminin is degraded by the proteasome (Drosophila melanogaster)
26S proteasome [nucleoplasm] (Drosophila melanogaster)
20S core particle [nucleoplasm] (Drosophila melanogaster)
20S CP outer ring [nucleoplasm] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional regulation by RUNX2 (Drosophila melanogaster)
Regulation of RUNX2 expression and activity (Drosophila melanogaster)
26S proteasome degrades PolyUb-RUNX2 (Drosophila melanogaster)
26S proteasome [nucleoplasm] (Drosophila melanogaster)
20S core particle [nucleoplasm] (Drosophila melanogaster)
20S CP outer ring [nucleoplasm] (Drosophila melanogaster)
Transcriptional regulation by RUNX3 (Drosophila melanogaster)
Regulation of RUNX3 expression and activity (Drosophila melanogaster)
Polyubiquitinated RUNX3 is degraded by the proteasome (Drosophila melanogaster)
26S proteasome [nucleoplasm] (Drosophila melanogaster)
20S core particle [nucleoplasm] (Drosophila melanogaster)
20S CP outer ring [nucleoplasm] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Hedgehog (Drosophila melanogaster)
Hedgehog 'on' state (Drosophila melanogaster)
GLI2,3 are degraded by the proteasome (Drosophila melanogaster)
26S proteasome [nucleoplasm] (Drosophila melanogaster)
20S core particle [nucleoplasm] (Drosophila melanogaster)
20S CP outer ring [nucleoplasm] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Homologues of PSMA7 [nucleoplasm]
(Drosophila melanogaster)
Prosalpha1 [nucleoplasm]
(Drosophila melanogaster)
Prosalpha2 [nucleoplasm]
(Drosophila melanogaster)
Prosalpha3 [nucleoplasm]
(Drosophila melanogaster)
Prosalpha5 [nucleoplasm]
(Drosophila melanogaster)
Prosalpha6 [nucleoplasm]
(Drosophila melanogaster)
Prosalpha7 [nucleoplasm]
(Drosophila melanogaster)
Participates
as a component of
20S core particle [nucleoplasm] (Drosophila melanogaster)
Inferred From
20S CP outer ring [nucleoplasm]
(Homo sapiens)
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text