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Iru [cytosol]
Stable Identifier
R-DME-975993
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
PJA2, Q9VHI7
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Class I MHC mediated antigen processing & presentation (Drosophila melanogaster)
Antigen processing: Ubiquitination & Proteasome degradation (Drosophila melanogaster)
Interaction of E3 with substrate and E2-Ub complex (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Iru [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Iru [cytosol] (Drosophila melanogaster)
Polyubiquitination of substrate (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Iru [cytosol] (Drosophila melanogaster)
E3:K48-polyubiquitinated substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Iru [cytosol] (Drosophila melanogaster)
E3:Ub:substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Iru [cytosol] (Drosophila melanogaster)
Release of E3 from polyubiquitinated substrate (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Iru [cytosol] (Drosophila melanogaster)
E3:K48-polyubiquitinated substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Iru [cytosol] (Drosophila melanogaster)
Transfer of Ub from E2 to substrate and release of E2 (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Iru [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Iru [cytosol] (Drosophila melanogaster)
E3:Ub:substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Iru [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VHI7
Gene Names
Iru
Reference Genes
BioGPS Gene:41080 Iru
ENSEMBL:FBgn0037653
FlyBase:FBgn0037653
KEGG:dme:Dmel_CG11982 Iru
Monarch:41080 Iru
NCBI Gene:41080 Iru
UCSC:Q9VHI7 Iru
Reference Transcript
RefSeq:NM_141602.4 Iru
Other Identifiers
141228_at
1635513_at
41080
GO:0000209
GO:0003824
GO:0004842
GO:0005515
GO:0005575
GO:0005737
GO:0008270
GO:0016567
GO:0016740
GO:0046872
GO:0051865
GO:0061630
GO:0140096
Participates
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Other forms of this molecule
Iru [cytosol]
Inferred From
PJA2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_649859.1
ENSEMBL
FBgn0037653
,
FBpp0081445
,
FBtr0081965
IntEnz
2.3.2.27
FlyBase
FBgn0037653
PRO
Q9VHI7
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P25867 eff
4
EFF [cytosol]
(R-DME-205773)
eff [cytosol]
(R-DME-8864160)
eff [nucleoplasm]
(R-DME-174197)
eff [cytosol]
(R-DME-174236)
0.488
2
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