Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
Thor [cytosol]
Stable Identifier
R-DME-72580
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
EIF4EBP1, Q9XZ56
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Drosophila melanogaster)
Translation (Drosophila melanogaster)
Eukaryotic Translation Initiation (Drosophila melanogaster)
Cap-dependent Translation Initiation (Drosophila melanogaster)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Drosophila melanogaster)
Release of eIF4E from the inactive eIF4E:4E-BP complex (Drosophila melanogaster)
Thor [cytosol] (Drosophila melanogaster)
eIF4E:4E-BP [cytosol] (Drosophila melanogaster)
Thor [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
MTOR signalling (Drosophila melanogaster)
mTORC1-mediated signalling (Drosophila melanogaster)
Phosphorylation of 4E-BP1 by activated mTORC1 (Drosophila melanogaster)
eIF4E:4E-BP [cytosol] (Drosophila melanogaster)
Thor [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9XZ56 Thor
Gene Names
Thor, CG8846
Chain
chain:1-117
Reference Genes
BioGPS Gene:33569 Thor
CTD Gene:33569 Thor
KEGG Gene (Drosophila melanogaster):Dmel_CG8846 Thor
Monarch:33569 Thor
NCBI Gene:33569 Thor
UCSC:Q9XZ56 Thor
Reference Transcript
RefSeq:NM_001298659.1 Thor
RefSeq:NM_057947.4 Thor
Other Identifiers
153432_at
1635900_at
33569
GO:0001558
GO:0002376
GO:0005515
GO:0005737
GO:0005829
GO:0006417
GO:0006629
GO:0006641
GO:0006955
GO:0006979
GO:0008190
GO:0008286
GO:0008340
GO:0009617
GO:0017148
GO:0019731
GO:0023052
GO:0031594
GO:0032869
GO:0034330
GO:0034599
GO:0042594
GO:0045087
GO:0045182
GO:0045792
GO:0045947
GO:0048010
GO:0065003
GO:0070129
GO:0098542
GO:0098793
GO:0098978
GO:0099577
GO:0140053
GO:1905536
GO:2000331
Participates
as an output of
Release of eIF4E from the inactive eIF4E:4E-BP complex (Drosophila melanogaster)
as a component of
eIF4E:4E-BP [cytosol] (Drosophila melanogaster)
Other forms of this molecule
Phosphorylated D4EBP [cytosol]
THOR [cytosol]
phospho-Thor [cytosol]
Inferred From
EIF4EBP1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_477295.1
,
NP_001285588.1
Flybase
FBgn0261560
PDB
4UE8
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P48598 eIF4E1
2
EIF-4E [cytosol]
(R-DME-110511)
EIF4E [cytosol]
(R-DME-72578)
0.765
6
UniProt:Q86B79
1
unk [cytosol]
(R-DME-8850900)
0.527
2
UniProt:Q24246-2 SW
0.462
2
UniProt:Q9VT45 Q9VT45
0.462
2
UniProt:Q9VC45 ASP
0.462
2
UniProt:Q9VCD8
4
SMC1 [cytosol]
(R-DME-2484798)
SMC1 [chromosome]
(R-DME-1638774)
SMC1 [chromosome, centromeric region]
(R-DME-2466015)
SMC1 [nucleoplasm]
(R-DME-64561)
0.462
2
IntAct:EBI-9919031 Q7KUY3
0.462
2
UniProt:Q9VEZ3 MSPS
0.462
2
UniProt:Q8IM86 Q8IM86
0.462
2
UniProt:Q9VV09 Q9VV09
0.462
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text