Reactome | CDK4 [cytosol]

CDK4 [cytosol]

Stable Identifier

R-DME-68330

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

Q7K306

Locations in the PathwayBrowser

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Immune System (Drosophila melanogaster)

- Adaptive Immune System (Drosophila melanogaster)
  - Regulation of T cell activation by CD28 family (Drosophila melanogaster)
    - Co-inhibition by PD-1 (Drosophila melanogaster)
      - Regulation of PD-L1(CD274) expression (Drosophila melanogaster)
        
        Regulation of PD-L1(CD274) Post-translational modification (Drosophila melanogaster)
        
        SPOP-mediated proteasomal degradation of PD-L1(CD274) (Drosophila melanogaster)
        
        CDK4:CCND1 phosphorylates SPOP (Drosophila melanogaster)
        
        CDK4 [cytosol] (Drosophila melanogaster)
        
        CDK4:CCND1 [cytosol] (Drosophila melanogaster)
        
        CDK4 [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q7K306

Reference Genes

BioGPS Gene:36854

ENSEMBL:FBgn0016131

FlyBase:FBgn0016131

KEGG:dme:Dmel_CG5072

Monarch:36854

NCBI Gene:36854

UCSC:Q7K306

Reference Transcript

Other Identifiers

154563_at

1639347_s_at

36854

GO:0000082

GO:0000166

GO:0000307

GO:0003824

GO:0004672

GO:0004674

GO:0004693

GO:0005524

GO:0005634

GO:0005737

GO:0006468

GO:0007165

GO:0007350

GO:0007424

GO:0010389

GO:0010468

GO:0010821

GO:0016301

GO:0016740

GO:0030307

GO:0030332

GO:0046427

GO:0048856

GO:0051726

GO:0140096

GO:1904263

Participates

as a component of

as a member of

CDK4,CDK6 [cytosol] (Drosophila melanogaster)

Other forms of this molecule

CDK6 [cytosol]

CDK4 [nucleoplasm]

CDK6 [nucleoplasm]

phospho-p-T172-CDK4 [nucleoplasm]

phospho-p-T177-CDK6 [nucleoplasm]

Inferred From

CDK4 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001286494.1, NP_001286493.1, NP_477196.1, NP_725594.1, NP_725595.1

FlyBase

FBgn0016131