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phospho-p-T177-CDK6 [nucleoplasm]
Stable Identifier
R-DME-69628
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
Q7K306
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
Mitotic G1 phase and G1/S transition (Drosophila melanogaster)
G1 Phase (Drosophila melanogaster)
Cyclin D associated events in G1 (Drosophila melanogaster)
CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND1 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND2 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND3 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND1 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND2 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND3 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND1 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND2 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND3 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
Drug-mediated inhibition of CDK4/CDK6 activity (Drosophila melanogaster)
CDK6 inhibitors bind CDK6 (Drosophila melanogaster)
p-T177-CDK6:CCND [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND1 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND2 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND3 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND:CDK6 inhibitors [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND1:CDK6 inhibitors (CCND1) [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND1 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND2:CDK6 inhibitors (CCND2) [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND2 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND3:CDK6 inhibitors (CCND3) [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND3 [nucleoplasm] (Drosophila melanogaster)
phospho-p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7K306
Reference Genes
BioGPS Gene:36854
ENSEMBL:FBgn0016131
FlyBase:FBgn0016131
KEGG:dme:Dmel_CG5072
Monarch:36854
NCBI Gene:36854
UCSC:Q7K306
Reference Transcript
RefSeq:NM_166185.2
RefSeq:NM_166184.2
RefSeq:NM_001299565.1
RefSeq:NM_001299564.1
RefSeq:NM_057848.3
Other Identifiers
154563_at
1639347_s_at
36854
GO:0000082
GO:0000307
GO:0003824
GO:0004672
GO:0004674
GO:0004693
GO:0005524
GO:0005634
GO:0005737
GO:0006468
GO:0007165
GO:0007350
GO:0007424
GO:0008353
GO:0010389
GO:0010468
GO:0010821
GO:0016592
GO:0016740
GO:0030307
GO:0030332
GO:0043226
GO:0046427
GO:0048856
GO:0051726
GO:0140096
GO:1904263
Participates
as a component of
p-T177-CDK6:CCND3 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND2 [nucleoplasm] (Drosophila melanogaster)
p-T177-CDK6:CCND1 [nucleoplasm] (Drosophila melanogaster)
as a candidate of
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Drosophila melanogaster)
Other forms of this molecule
CDK4 [cytosol]
CDK6 [cytosol]
CDK4 [nucleoplasm]
CDK6 [nucleoplasm]
phospho-p-T172-CDK4 [nucleoplasm]
Inferred From
p-T177-CDK6 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 177 (in Homo sapiens)
Coordinate
177
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_477196.1
,
NP_001286494.1
,
NP_001286493.1
,
NP_725595.1
,
NP_725594.1
ENSEMBL
FBpp0086251
,
FBpp0086250
,
FBtr0340063
,
FBtr0345340
,
FBtr0087103
,
FBpp0086249
,
FBtr0087102
,
FBpp0311495
,
FBtr0087104
,
FBpp0309069
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