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Drice [cytosol]
Stable Identifier
R-DME-57031
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
CASP8(1-479), O01382
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Drosophila melanogaster)
Apoptosis (Drosophila melanogaster)
Caspase activation via extrinsic apoptotic signalling pathway (Drosophila melanogaster)
Caspase activation via Death Receptors in the presence of ligand (Drosophila melanogaster)
Dimerization of procaspase-8 (Drosophila melanogaster)
TNF-mediated dimerization of procaspase-8 (Drosophila melanogaster)
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Drice [cytosol] (Drosophila melanogaster)
TRADD:TRAF2:RIP1:FADD:CASP8(1-479) [cytosol] (Drosophila melanogaster)
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Drice [cytosol] (Drosophila melanogaster)
TRAF2:TRADD:RIP1:FADD:2xCASP8(1-479) [cytosol] (Drosophila melanogaster)
procaspase-8 dimer [cytosol] (Drosophila melanogaster)
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Drice [cytosol] (Drosophila melanogaster)
Regulation by c-FLIP (Drosophila melanogaster)
Caspase-8 and FLIP(L) processing at DISC (Drosophila melanogaster)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Drosophila melanogaster)
TRADD:TRAF2:RIP1:FADD:CASP8(1-479) [cytosol] (Drosophila melanogaster)
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Drice [cytosol] (Drosophila melanogaster)
FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Drosophila melanogaster)
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Drice [cytosol] (Drosophila melanogaster)
TRADD:TRAF2:RIP1:FADD:procaspase-8:FLIP(L) [cytosol] (Drosophila melanogaster)
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Drice [cytosol] (Drosophila melanogaster)
Regulated Necrosis (Drosophila melanogaster)
RIPK1-mediated regulated necrosis (Drosophila melanogaster)
Regulation of necroptotic cell death (Drosophila melanogaster)
CASP8 activity is inhibited (Drosophila melanogaster)
FLIP(L) and procaspase-8 form heterodimer (Drosophila melanogaster)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Drosophila melanogaster)
TRADD:TRAF2:RIP1:FADD:CASP8(1-479) [cytosol] (Drosophila melanogaster)
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Drice [cytosol] (Drosophila melanogaster)
TRADD:TRAF2:RIP1:FADD:CASP8(1-479) [cytosol] (Drosophila melanogaster)
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Drice [cytosol] (Drosophila melanogaster)
FLIP(S) and procaspase-8 form heterodimer (Drosophila melanogaster)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Drosophila melanogaster)
TRADD:TRAF2:RIP1:FADD:CASP8(1-479) [cytosol] (Drosophila melanogaster)
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Drice [cytosol] (Drosophila melanogaster)
TRADD:TRAF2:RIP1:FADD:CASP8(1-479) [cytosol] (Drosophila melanogaster)
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Drice [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Death Receptor Signaling (Drosophila melanogaster)
TNF signaling (Drosophila melanogaster)
Regulation of TNFR1 signaling (Drosophila melanogaster)
Caspase-8 and FLIP(L) processing at TNFR signaling complex (Drosophila melanogaster)
TRADD:TRAF2:RIP1:FADD:procaspase-8:FLIP(L) [cytosol] (Drosophila melanogaster)
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Drice [cytosol] (Drosophila melanogaster)
FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Drosophila melanogaster)
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Drice [cytosol] (Drosophila melanogaster)
TRADD:TRAF2:RIP1:FADD:procaspase-8:FLIP(L) [cytosol] (Drosophila melanogaster)
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Drice [cytosol] (Drosophila melanogaster)
OPTN binds CASP8 (Drosophila melanogaster)
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Drice [cytosol] (Drosophila melanogaster)
OPTN:CASP8 [cytosol] (Drosophila melanogaster)
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Drice [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:O01382
Gene Names
Drice
Reference Genes
BioGPS Gene:43514 Drice
CTD Gene:43514 Drice
ENSEMBL:FBgn0019972
FlyBase:FBgn0019972
KEGG:dme:Dmel_CG7788 Drice
Monarch:43514 Drice
NCBI Gene:43514 Drice
UCSC:O01382 Drice
Reference Transcript
RefSeq:NM_079827.3 Drice
Other Identifiers
152941_at
1634668_at
43514
GO:0004197
GO:0005515
GO:0005634
GO:0005737
GO:0005886
GO:0006508
GO:0006915
GO:0008233
GO:0008234
GO:0010165
GO:0010623
GO:0012501
GO:0016322
GO:0016787
GO:0022414
GO:0030154
GO:0031625
GO:0035070
GO:0043525
GO:0045476
GO:0045751
GO:0046667
GO:0046672
GO:0048515
GO:0061060
GO:0097153
GO:0097194
GO:0097200
GO:1990525
Participates
as a member of
Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
Other forms of this molecule
Drice [cytosol]
Drice [cytosol]
Drice [cytosol]
Drice [cytosol]
Drice [cytosol]
Drice [cytosol]
Drice [mitochondrial outer membrane]
Drice [mitochondrial outer membrane]
Drice [cytosol]
Drice [cytosol]
Drice [nucleoplasm]
Drice [nucleoplasm]
Drice [cytosol]
Drice [cytosol]
Drice [cytosol]
Drice [cytosol]
Drice [cytosol]
Drice [cytosol]
Drice [nucleoplasm]
Drice [nucleoplasm]
Drice [nucleoplasm]
Drice [nucleoplasm]
Drice [cytosol]
Drice [cytosol]
Drice [cytosol]
Inferred From
CASP8(1-479) [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_524551.2
ENSEMBL
FBgn0019972
,
FBpp0084848
,
FBtr0085482
PRO
O01382
FlyBase
FBgn0019972
PDB
3SIP
,
3SIR
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9XYF4
1
Dronc [cytosol]
(R-DME-5657970)
0.722
4
UniProt:Q24307 Diap2
10
IAP2 [cytosol]
(R-DME-205735)
XIAP [nucleoplasm]
(R-DME-3322366-2)
BIRC2(1-372) [cytosol]
(R-DME-202913)
BIRC2(373-618) [cytosol]
(R-DME-202931)
K48pUb-BIRC2 [cytosol]
(R-DME-5675479)
K48pUb-BIRC3 [cytosol]
(R-DME-5675478-2)
K48pUb-XIAP [cytosol]
(R-DME-5675477-2)
XIAP [cytosol]
(R-DME-50849-2)
BIRC2 [cytosol]
(R-DME-50847)
BIRC3 [cytosol]
(R-DME-50845-2)
0.544
4
UniProt:Q24306 Diap1
7
BIRC3 [cytosol]
(R-DME-50845)
XIAP [cytosol]
(R-DME-50849)
K48pUb-XIAP [cytosol]
(R-DME-5675477)
K48pUb-BIRC3 [cytosol]
(R-DME-5675478)
XIAP [nucleoplasm]
(R-DME-3322366)
TH [cytosol]
(R-DME-390182)
Phospho TH [cytosol]
(R-DME-390103)
0.544
3
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