Reactome | Drice [cytosol]

Drice [cytosol]

Stable Identifier

R-DME-57021

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

CASP3(1-277), O01382

Locations in the PathwayBrowser

Expand all

Programmed Cell Death (Drosophila melanogaster)

- Apoptosis (Drosophila melanogaster)
  - Intrinsic Pathway for Apoptosis (Drosophila melanogaster)
    - Apoptotic factor-mediated response (Drosophila melanogaster)
      - Cytochrome c-mediated apoptotic response (Drosophila melanogaster)
        
        Activation of caspases through apoptosome-mediated cleavage (Drosophila melanogaster)
        
        Cleavage of Procaspase-3 by the apoptosome (Drosophila melanogaster)
        
        CASP3(1-277) dimer [cytosol] (Drosophila melanogaster)
        
        Homologues of CASP3(1-277) [cytosol] (Drosophila melanogaster)
        
        Drice [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:O01382

Gene Names

Drice

Reference Genes

BioGPS Gene:43514 Drice

CTD Gene:43514 Drice

ENSEMBL:FBgn0019972

FlyBase:FBgn0019972

KEGG:dme:Dmel_CG7788 Drice

Monarch:43514 Drice

NCBI Gene:43514 Drice

UCSC:O01382 Drice

Reference Transcript

RefSeq:NM_079827.3 Drice

Other Identifiers

152941_at

1634668_at

43514

GO:0004197

GO:0005515

GO:0005634

GO:0005737

GO:0005886

GO:0006508

GO:0006915

GO:0008233

GO:0008234

GO:0010165

GO:0010623

GO:0012501

GO:0016322

GO:0016787

GO:0022414

GO:0030154

GO:0031625

GO:0035070

GO:0043525

GO:0045476

GO:0045751

GO:0046667

GO:0046672

GO:0048515

GO:0061060

GO:0097153

GO:0097194

GO:0097200

GO:1990525

Participates

as a member of

Homologues of CASP3(1-277) [cytosol] (Drosophila melanogaster)

Other forms of this molecule

Drice [cytosol]

Drice [mitochondrial outer membrane]

Drice [cytosol]

Drice [nucleoplasm]

Drice [cytosol]

Drice [nucleoplasm]

Drice [cytosol]

Inferred From

CASP3(1-277) [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_524551.2

ENSEMBL

FBgn0019972, FBtr0085482, FBpp0084848

PRO

O01382

FlyBase

FBgn0019972

PDB

3SIP, 3SIR

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9XYF4	1	Dronc [cytosol] (R-DME-5657970)	0.722	4
UniProt:Q24307 Diap2	10	IAP2 [cytosol] (R-DME-205735) Diap2 [nucleoplasm] (R-DME-3322366-2) Diap2 [cytosol] (R-DME-202913) Diap2 [cytosol] (R-DME-202931) Diap2 [cytosol] (R-DME-5675479) Diap2 [cytosol] (R-DME-5675478-2) Diap2 [cytosol] (R-DME-5675477-2) Diap2 [cytosol] (R-DME-50849-2) Diap2 [cytosol] (R-DME-50847) Diap2 [cytosol] (R-DME-50845-2)	0.544	4
UniProt:Q24306 Diap1	7	Diap1 [cytosol] (R-DME-50845) Diap1 [cytosol] (R-DME-50849) Diap1 [cytosol] (R-DME-5675477) Diap1 [cytosol] (R-DME-5675478) Diap1 [nucleoplasm] (R-DME-3322366) TH [cytosol] (R-DME-390182) Phospho TH [cytosol] (R-DME-390103)	0.544	3

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