In the absence of ARM, GRO binds to PAN and inhibits transcription

Stable Identifier
R-DME-209322
Type
Reaction [binding]
Species
Drosophila melanogaster
Compartment
nucleoplasm
ReviewStatus
5/5
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In the absence of ARM, GRO binds to PAN and inhibits transcription
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In the absence of Armadillo (ARM) due to an active 'destruction complex' removing it in the cytoplasm, the protein Groucho (GRO) binds to Pangolin (PAN) and inhibits transcription.
Literature References
PubMed ID Title Journal Year
9783586 Drosophila Tcf and Groucho interact to repress Wingless signalling activity

Cavallo, RA, Polevoy, GA, Clevers, HC, Moline, MM, Roose, J, Bejsovec, A, Cox, RT, Peifer, M

Nature 1998
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Output
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as an event of
Authored
Williams, MG  (2006-07-26)
Reviewed
Nusse, R  (2008-01-19)
Created
Williams, MG  (2006-06-28)
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