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GRO [nucleoplasm]
Stable Identifier
R-DME-205750
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Wingless pathway (Drosophila melanogaster)
WG ligand bound to FZ receptors (Drosophila melanogaster)
Transcription activation by ARM (Drosophila melanogaster)
ARM displaces GRO and binds to PAN which activates transcription (Drosophila melanogaster)
GRO [nucleoplasm] (Drosophila melanogaster)
GRO:PAN [nucleoplasm] (Drosophila melanogaster)
GRO [nucleoplasm] (Drosophila melanogaster)
WG ligand not bound to FZ receptors (Drosophila melanogaster)
In the absence of ARM, GRO binds to PAN and inhibits transcription (Drosophila melanogaster)
GRO [nucleoplasm] (Drosophila melanogaster)
GRO:PAN [nucleoplasm] (Drosophila melanogaster)
GRO [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P16371 gro
Gene Names
gro, E(spl)m9/m10, CG8384
Chain
chain:1-730
Reference Genes
BioGPS Gene:43162 gro
KEGG Gene (Drosophila melanogaster):Dmel_CG8384 gro
Monarch:43162 gro
NCBI Gene:43162 gro
UCSC:P16371 gro
Reference Transcript
RefSeq:NM_079790.5 gro
RefSeq:NM_001202364.1 gro
RefSeq:NM_206575.3 gro
RefSeq:NM_170255.4 gro
RefSeq:NM_170256.2 gro
RefSeq:NM_170254.3 gro
Other Identifiers
142039_s_at
43162
GO:0000122
GO:0003714
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0006351
GO:0006355
GO:0007173
GO:0007399
GO:0007541
GO:0008134
GO:0008293
GO:0008543
GO:0016055
GO:0022414
GO:0023052
GO:0030154
GO:0032991
GO:0043226
GO:0045751
GO:0045892
GO:0048856
GO:0071837
GO:0071906
GO:0090090
GO:0140110
GO:0140297
Participates
as an output of
ARM displaces GRO and binds to PAN which activates transcription (Drosophila melanogaster)
as a component of
GRO:PAN [nucleoplasm] (Drosophila melanogaster)
Aes:GRO [nucleoplasm] (Drosophila melanogaster)
as an input of
In the absence of ARM, GRO binds to PAN and inhibits transcription (Drosophila melanogaster)
Gro binds Aes (Drosophila melanogaster)
Other forms of this molecule
gro [nucleoplasm]
gro [nucleoplasm]
gro [nucleoplasm]
gro [nucleoplasm]
gro [nucleoplasm]
gro [nucleoplasm]
gro [nucleoplasm]
gro [nucleoplasm]
Cross References
RefSeq
NP_996298.1
,
NP_524514.2
,
NP_001189293.1
,
NP_733135.1
,
NP_733134.1
,
NP_733133.1
Flybase
FBgn0001139
PRO
P16371
Interactors (15)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P14003 HAIR
0.819
7
UniProt:Q01071 ESMD
0.668
4
UniProt:P10734
20
phospho-kni [nucleoplasm]
(R-DME-9024210)
kni [nucleoplasm]
(R-DME-6782984)
kni [cytosol]
(R-DME-5618118)
kni [cytosol]
(R-DME-5618122)
kni [cytosol]
(R-DME-8948964)
phospho-kni [nucleoplasm]
(R-DME-9841867)
phospho-kni [cytosol]
(R-DME-9841254)
kni [cytosol]
(R-DME-9020968)
kni [cytosol]
(R-DME-9020970)
kni [nucleoplasm]
(R-DME-3196163)
kni [nucleoplasm]
(R-DME-446168)
kni [nucleoplasm]
(R-DME-446165)
kni [cytosol]
(R-DME-5618082)
kni [nucleoplasm]
(R-DME-446174)
kni [plasma membrane]
(R-DME-9637787)
kni [plasma membrane]
(R-DME-9637786)
kni [plasma membrane]
(R-DME-9637788)
kni [plasma membrane]
(R-DME-9021059)
kni [plasma membrane]
(R-DME-9021053)
kni [plasma membrane]
(R-DME-9021057)
0.653
5
UniProt:P13098 ESM8
0.553
4
UniProt:Q01068 ESM3
0.553
4
UniProt:P13096 ESM5
0.553
3
UniProt:P91943 pan
1
PAN [nucleoplasm]
(R-DME-205730)
0.553
3
UniProt:Q62233 SIX3
0.544
2
UniProt:Q9W4S7
2
Myc [nucleoplasm]
(R-DME-452357)
Myc [nucleoplasm]
(R-DME-188379)
0.524
3
UniProt:O97102
6
Sumo [nucleoplasm]
(R-DME-2990830)
Sumo [nucleoplasm]
(R-DME-2990837)
Sumo [nucleoplasm]
(R-DME-2984281)
Sumo [nucleoplasm]
(R-DME-2984269)
Sumo [nucleoplasm]
(R-DME-3730611)
Sumo [nucleoplasm]
(R-DME-3730625)
0.524
2
UniProt:Q27350 SO
0.502
2
UniProt:Q26263 DPN
0.502
2
UniProt:P54366 GSC
0.502
2
UniProt:P22814
20
run [plasma membrane]
(R-DME-5667138)
phospho-run [nucleoplasm]
(R-DME-8878063)
phospho-run [nucleoplasm]
(R-DME-8937712)
run [nucleoplasm]
(R-DME-8934750)
phospho-run [nucleoplasm]
(R-DME-8939964-2)
phospho-run [nucleoplasm]
(R-DME-9014875-2)
run [nucleoplasm]
(R-DME-9008125-2)
run [nucleoplasm]
(R-DME-9008124-2)
run [cytosol]
(R-DME-9008082-2)
run [nucleoplasm]
(R-DME-8865393-2)
run [cytosol]
(R-DME-8937797-2)
run [nucleoplasm]
(R-DME-8951965-2)
run [nucleoplasm]
(R-DME-8865295)
run [cytosol]
(R-DME-8952400-2)
run [nucleoplasm]
(R-DME-8952387-2)
phospho-run [cytosol]
(R-DME-8937805-2)
run [nucleoplasm]
(R-DME-8952417-2)
run [nucleoplasm]
(R-DME-9007691-2)
run [nucleoplasm]
(R-DME-9007689-2)
run [cytosol]
(R-DME-9007987-2)
0.502
2
UniProt:Q01196-1 RUNX1
0.488
4
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