Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
IMD [cytosol]
Stable Identifier
R-DME-206183
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Imd pathway (Drosophila melanogaster)
Catalytic processing of the nuclear factor, REL (Drosophila melanogaster)
Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex' (Drosophila melanogaster)
Activated Phospho IRD5:KEY dimer phosphorylates REL in the PGN:PGRP-LC oligomer receptor 'signalling complex' (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD:Phospho REL [plasma membrane] (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD:REL [plasma membrane] (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
Activated Phospho IRD5:KEY dimer phosphorylates REL in the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD:Phospho REL [cytosol] (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD:REL [cytosol] (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
Phosphorylated REL is cleaved by and dissociates from DREDD (Drosophila melanogaster)
Phosphorylated REL is cleaved by and dissociates from DREDD in the PGN:PGRP-LC oligomer receptor 'signalling complex' (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD [plasma membrane] (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD:Phospho REL [plasma membrane] (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
Phosphorylated REL is cleaved by and dissociates from DREDD in the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD [cytosol] (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD:Phospho REL [cytosol] (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
Formation of the PGN:PGRP-LC/LE receptor 'signalling complex' (Drosophila melanogaster)
Assembly of the PGN:PGRP-LC/LE receptor 'signalling complex' (Drosophila melanogaster)
Assembly of the PGN:PGRP-LC oligomer receptor 'signalling complex' (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD [plasma membrane] (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
Assembly of the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD [cytosol] (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex' (Drosophila melanogaster)
REL binds to DREDD in the PGN:PGRP-LC oligomer receptor 'signalling complex' (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD [plasma membrane] (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD:REL [plasma membrane] (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
REL binds to monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD [cytosol] (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD:REL [cytosol] (Drosophila melanogaster)
IMD [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7K4Z4 imd
Gene Names
imd, CG5576
Chain
chain:1-273
Reference Genes
BioGPS Gene:44339 imd
CTD Gene:44339 imd
KEGG Gene (Drosophila melanogaster):Dmel_CG5576 imd
Monarch:44339 imd
NCBI Gene:44339 imd
UCSC:Q7K4Z4 imd
Reference Transcript
RefSeq:NM_133166.4 imd
RefSeq:NM_001299643.1 imd
Other Identifiers
141930_at
152815_at
1637332_at
44339
GO:0002230
GO:0002376
GO:0002803
GO:0005515
GO:0005829
GO:0006955
GO:0006959
GO:0006963
GO:0006964
GO:0007165
GO:0007399
GO:0009605
GO:0009617
GO:0019731
GO:0023052
GO:0035556
GO:0045087
GO:0045089
GO:0048856
GO:0050829
GO:0061057
GO:0070513
GO:0098542
Participates
as an input of
Assembly of the PGN:PGRP-LC oligomer receptor 'signalling complex' (Drosophila melanogaster)
Assembly of the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' (Drosophila melanogaster)
as a component of
PGN:PGRP-LC oligomer:IMD:BG4:DREDD:REL [plasma membrane] (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD [plasma membrane] (Drosophila melanogaster)
PGN:PGRP-LC oligomer:IMD:BG4:DREDD:Phospho REL [plasma membrane] (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD:REL [cytosol] (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD [cytosol] (Drosophila melanogaster)
Mono PGN:PGRP-LE oligomer:IMD:BG4:DREDD:Phospho REL [cytosol] (Drosophila melanogaster)
Cross References
RefSeq
NP_001286572.1
,
NP_573394.1
Flybase
FBgn0013983
PRO
Q7K4Z4
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9V3B4 Fadd
2
BG4 [cytosol]
(R-DME-205887)
Fadd [cytosol]
(R-DME-54639)
0.502
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text