3CLp dimer:3CLp inhibitors [cytosol]

Stable Identifier
R-COV-9694375
Type
Complex
Species
Severe acute respiratory syndrome coronavirus 2
Compartment
Literature References
PubMed ID Title Journal Year
32272481 Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

Duan, Y, Zhang, L, Jin, Z, Jiang, R, Shi, Z, Deng, Y, Qin, C, Zhang, B, Yang, H, Wang, L, Xu, Y, Liu, H, You, T, Du, X, Peng, C, Liu, M, Liu, X, Xu, W, Yang, X, Yang, X, Liu, F, Li, X, Rao, Z, Xiao, G, Zhao, Y, Jiang, H, Liu, X, Bai, F, Yu, J, Yang, K, Guddat, LW

Nature 2020
  Considerations for the Discovery and Development of 3-Chymotrypsin-Like Cysteine Protease Inhibitors Targeting SARS-CoV-2 Infection

Deval, J, Vandyck, K

   
32541865 Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease

Sacco, MD, Marty, MT, Chen, Y, Townsend, JA, Wang, J, Zhang, X, Hu, Y, Hurst, B, Ma, C, Szeto, T, Tarbet, B

Cell Res 2020
Participants
Participates
This entity regulates
Disease
Name Identifier Synonyms
COVID-19 DOID:0080600 2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
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