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F5 [endoplasmic reticulum lumen]
Stable Identifier
R-CFA-5689447
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
endoplasmic reticulum lumen
Synonyms
Factor V precursor, A0A8I3MLH1
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Asparagine N-linked glycosylation (Canis familiaris)
Transport to the Golgi and subsequent modification (Canis familiaris)
ER to Golgi Anterograde Transport (Canis familiaris)
COPII-mediated vesicle transport (Canis familiaris)
Inner coat assembly and cargo binding (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
Loss of SAR1B GTPase (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
SEC31:SEC13 and v-SNARE recruitment (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
Vesicle budding (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
Cargo concentration in the ER (Canis familiaris)
Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
Inner coat assembly and cargo binding (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
Post-translational protein phosphorylation (Canis familiaris)
FAM20C phosphorylates FAM20C substrates (Canis familiaris)
FAM20C:FAM20C substrates [endoplasmic reticulum lumen] (Canis familiaris)
FAM20C substrates [endoplasmic reticulum lumen] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) (Canis familiaris)
FAM20C phosphorylates FAM20C substrates (Canis familiaris)
FAM20C:FAM20C substrates [endoplasmic reticulum lumen] (Canis familiaris)
FAM20C substrates [endoplasmic reticulum lumen] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
Vesicle-mediated transport (Canis familiaris)
Membrane Trafficking (Canis familiaris)
ER to Golgi Anterograde Transport (Canis familiaris)
COPII-mediated vesicle transport (Canis familiaris)
Inner coat assembly and cargo binding (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
Loss of SAR1B GTPase (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
SEC31:SEC13 and v-SNARE recruitment (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
Vesicle budding (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
Cargo concentration in the ER (Canis familiaris)
Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
Inner coat assembly and cargo binding (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
F5 [endoplasmic reticulum lumen] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3MLH1
Gene Names
F5
Reference Genes
ENSEMBL:ENSCAFG00845002341.1
UCSC:A0A8I3MLH1 F5
Other Identifiers
CfaAffx.23403.1.S1_s_at
GO:0003013
GO:0005507
GO:0005576
GO:0005615
GO:0007596
GO:0008015
GO:0031091
GO:0031410
GO:0043226
Participates
as a component of
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Canis familiaris)
as an input of
Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Canis familiaris)
as a member of
FAM20C substrates [endoplasmic reticulum lumen] (Canis familiaris)
Other forms of this molecule
F5 [extracellular region]
F5 [extracellular region]
F5 [extracellular region]
F5 [extracellular region]
F5 [endoplasmic reticulum-Golgi intermediate compartment membrane]
F5 [COPII-coated ER to Golgi transport vesicle]
phospho-F5 [endoplasmic reticulum lumen]
F5 [extracellular region]
F5 [extracellular region]
F5 [platelet alpha granule lumen]
F5 [extracellular region]
F5 [extracellular region]
F5 [plasma membrane]
F5 [plasma membrane]
Inferred From
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen]
(Homo sapiens)
Factor V precursor [endoplasmic reticulum lumen]
(Homo sapiens)
Cross References
ENSEMBL
ENSCAFP00845003315
,
ENSCAFG00845002341
,
ENSCAFT00845004145
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