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glycosylated FV, FVIII precursor [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-5694189
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
Inner coat assembly and cargo binding (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
Loss of SAR1B GTPase (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
SEC31:SEC13 and v-SNARE recruitment (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
Vesicle budding (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
Cargo concentration in the ER (Homo sapiens)
Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
Inner coat assembly and cargo binding (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
Inner coat assembly and cargo binding (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
Loss of SAR1B GTPase (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
SEC31:SEC13 and v-SNARE recruitment (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
Vesicle budding (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
Cargo concentration in the ER (Homo sapiens)
Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
Inner coat assembly and cargo binding (Homo sapiens)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Homo sapiens)
Participants
members
Factor V precursor [endoplasmic reticulum lumen]
(Homo sapiens)
Factor VIII precursor [endoplasmic reticulum lumen]
(Homo sapiens)
Participates
as a component of
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Homo sapiens)
as an input of
Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Homo sapiens)
Inferred To
F8 [endoplasmic reticulum lumen]
(Rattus norvegicus)
f5 [endoplasmic reticulum lumen]
(Danio rerio)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen]
(Bos taurus)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen]
(Gallus gallus)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen]
(Mus musculus)
F5 [endoplasmic reticulum lumen]
(Canis familiaris)
F5 [endoplasmic reticulum lumen]
(Sus scrofa)
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