Reactome | smo-1 [nucleoplasm]

smo-1 [nucleoplasm]

Stable Identifier

R-CEL-3730622

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

UBE2I-G97-SUMO1, P55853

Locations in the PathwayBrowser

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DNA Repair (Caenorhabditis elegans)

- Nucleotide Excision Repair (Caenorhabditis elegans)
  - Global Genome Nucleotide Excision Repair (GG-NER) (Caenorhabditis elegans)
    - Formation of Incision Complex in GG-NER (Caenorhabditis elegans)
      - SUMOylation of XPC (Caenorhabditis elegans)
        
        SUMO1,2,3:UBE2I [nucleoplasm] (Caenorhabditis elegans)
        
        SUMO1:C93-UBE2I [nucleoplasm] (Caenorhabditis elegans)
        
        smo-1 [nucleoplasm] (Caenorhabditis elegans)

Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - Generic Transcription Pathway (Caenorhabditis elegans)
    - Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Caenorhabditis elegans)
      - Negative regulation of activity of TFAP2 (AP-2) family transcription factors (Caenorhabditis elegans)
        
        SUMOylation of TFAP2C with SUMO1 (Caenorhabditis elegans)
        
        SUMO1:C93-UBE2I [nucleoplasm] (Caenorhabditis elegans)
        
        smo-1 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:P55853

Gene Names

smo-1

Reference Genes

BioGPS Gene:266820 smo-1

ENSEMBL:WBGene00004888

KEGG:cel:CELE_K12C11.2 smo-1

Monarch:266820 smo-1

NCBI Gene:266820 smo-1

UCSC:P55853 smo-1

Wormbase:WBGene00004888

Wormbase:WBGene00004888 smo-1

Reference Transcript

RefSeq:NM_058441.7 smo-1

Other Identifiers

266820

GO:0000122

GO:0002119

GO:0005515

GO:0005634

GO:0005694

GO:0005737

GO:0005813

GO:0005815

GO:0005819

GO:0005856

GO:0006355

GO:0007080

GO:0009792

GO:0010468

GO:0016605

GO:0016925

GO:0031386

GO:0031647

GO:0034502

GO:0042802

GO:0043226

GO:0044389

GO:0045892

GO:0046716

GO:0048856

GO:0051306

GO:0070194

GO:0071965

GO:0110039

Participates

as a component of

SUMO1:C93-UBE2I [nucleoplasm] (Caenorhabditis elegans)

Other forms of this molecule

smo-1 [cytosol]

smo-1 [nucleoplasm]

Inferred From

UBE2I-G97-SUMO1 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

Inter-chain Crosslink via S-(glycyl)-L-cysteine (Cys-Gly) at 97 and 93 (in Homo sapiens)

Coordinate

PsiMod Name

S-(glycyl)-L-cysteine (Cys-Gly)

PsiMod Definition

A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.

Cross References

RefSeq

NP_490842.1

ENSEMBL

K12C11.2.1, K12C11.2.1, WBGene00004888

PRO

P55853

PDB

5XQM

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q94420	3	mel-26 [nucleoplasm] (R-CEL-5635035-5) mel-26 [cytosol] (R-CEL-9929374-5) mel-26 [cytosol] (R-CEL-9929375-5)	0.778	5
UniProt:P55853	5	smo-1 [cytosol] (R-CEL-4656941) smo-1 [nucleoplasm] (R-CEL-3730622) smo-1 [nucleoplasm] (R-CEL-3730616) smo-1 [nucleoplasm] (R-CEL-877304) smo-1 [nucleoplasm] (R-CEL-2990831)	0.712	4
UniProt:Q95017	6	ubc-9 [nucleoplasm] (R-CEL-4085358) ubc-9 [cytosol] (R-CEL-4656944) ubc-9 [cytosol] (R-CEL-4655342) ubc-9 [cytosol] (R-CEL-4656909) ubc-9 [nucleoplasm] (R-CEL-3730617) ubc-9 [nucleoplasm] (R-CEL-912481)	0.712	5
UniProt:P90740 FAN1			0.621	3
UniProt:Q23158	8	atn-1 [cytosol] (R-CEL-354096) atn-1 [extracellular region] (R-CEL-349722) atn-1 [extracellular region] (R-CEL-349725) atn-1 [extracellular region] (R-CEL-349729) atn-1 [platelet alpha granule lumen] (R-CEL-349727) atn-1 [platelet alpha granule lumen] (R-CEL-349724) atn-1 [platelet alpha granule lumen] (R-CEL-198240) atn-1 [cytosol] (R-CEL-390562)	0.621	3
UniProt:O16299	1	FIGNL1 [nucleoplasm] (R-CEL-9853365)	0.553	2
UniProt:Q18994	1	eif-2bepsilon [cytosol] (R-CEL-72523)	0.488	2
UniProt:Q9NF71	1	RCOR1 [nucleoplasm] (R-CEL-996766-4)	0.488	2
UniProt:Q20952	2	add-2 [cytosol] (R-CEL-5226994) add-2 [cytosol] (R-CEL-420043)	0.488	2
UniProt:Q9NA84 Q9NA84			0.488	2
UniProt:O45548 O45548			0.488	2
UniProt:W03G1.4 Q3V5H0			0.488	2
UniProt:H2KYD4 H2KYD4			0.488	2
UniProt:G5EFR3 G5EFR3			0.488	2
UniProt:Q17987 Q17987			0.488	2
UniProt:Q9GZG5 Q9GZG5			0.488	2
UniProt:G5EF87 G5EF87			0.488	2
UniProt:A5JYT9 A5JYT9			0.488	2
UniProt:Q94361	5	monoSUMO1-K35-PIAS4 [nucleoplasm] (R-CEL-3968415) PIAS2-1 [nucleoplasm] (R-CEL-2993785) PIAS3 [nucleoplasm] (R-CEL-2993764) PIAS1 [nucleoplasm] (R-CEL-877307) PIAS4 [nucleoplasm] (R-CEL-2993789)	0.488	2