Reactome | mel-26 [cytosol]

mel-26 [cytosol]

Stable Identifier

R-CEL-9929374-5

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

Q94420

Locations in the PathwayBrowser

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Immune System (Caenorhabditis elegans)

- Adaptive Immune System (Caenorhabditis elegans)
  - Regulation of T cell activation by CD28 family (Caenorhabditis elegans)
    - Co-inhibition by PD-1 (Caenorhabditis elegans)
      - Regulation of PD-L1(CD274) expression (Caenorhabditis elegans)
        
        Regulation of PD-L1(CD274) Post-translational modification (Caenorhabditis elegans)
        
        SPOP-mediated proteasomal degradation of PD-L1(CD274) (Caenorhabditis elegans)
        
        CDK4:CCND1 phosphorylates SPOP (Caenorhabditis elegans)
        
        Homologues of p-S6-SPOP [cytosol] (Caenorhabditis elegans)
        
        mel-26 [cytosol] (Caenorhabditis elegans)
        
        p-S6-SPOP binds YWHAG (Caenorhabditis elegans)
        
        Homologues of p-S6-SPOP [cytosol] (Caenorhabditis elegans)
        
        mel-26 [cytosol] (Caenorhabditis elegans)
        
        p-S6-SPOP:YWHAG [cytosol] (Caenorhabditis elegans)
        
        Homologues of p-S6-SPOP [cytosol] (Caenorhabditis elegans)
        
        mel-26 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q94420

Gene Names

mel-26

Reference Genes

BioGPS Gene:172737 mel-26

CTD Gene:172737 mel-26

ENSEMBL:WBGene00003209

KEGG:cel:CELE_ZK858.4 mel-26

Monarch:172737 mel-26

NCBI Gene:172737 mel-26

UCSC:Q94420 mel-26

Wormbase:WBGene00003209

Wormbase:WBGene00003209 K8F7T2

Reference Transcript

RefSeq:NM_060048.8 mel-26

Other Identifiers

172737

GO:0000132

GO:0000209

GO:0000793

GO:0005515

GO:0005634

GO:0005694

GO:0005737

GO:0005764

GO:0005829

GO:0005938

GO:0007010

GO:0009792

GO:0010507

GO:0016020

GO:0016567

GO:0019901

GO:0030162

GO:0030163

GO:0030307

GO:0030674

GO:0031430

GO:0031625

GO:0031674

GO:0032154

GO:0032888

GO:0042802

GO:0043161

GO:0048856

GO:0060090

GO:0065003

GO:0071233

GO:0071688

GO:0097602

GO:1904263

Participates

as a member of

Homologues of p-S6-SPOP [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

mel-26 [nucleoplasm]

mel-26 [cytosol]

Inferred From

p-S6-SPOP [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_492449.2

ENSEMBL

ZK858.4a.1, ZK858.4a.1, WBGene00003209

PRO

Q94420

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P55853	5	smo-1 [cytosol] (R-CEL-4656941) smo-1 [nucleoplasm] (R-CEL-3730622) smo-1 [nucleoplasm] (R-CEL-3730616) smo-1 [nucleoplasm] (R-CEL-877304) smo-1 [nucleoplasm] (R-CEL-2990831)	0.778	5
UniProt:Q17581	2	swsn-9 [nucleoplasm] (R-CEL-9932406) swsn-9 [nucleoplasm] (R-CEL-3222092)	0.553	2

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