Reactome | pop-1 [nucleoplasm]

pop-1 [nucleoplasm]

Stable Identifier

R-CEL-201923

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

TCF7L2, Q10666

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - Generic Transcription Pathway (Caenorhabditis elegans)
    - Transcriptional regulation by RUNX3 (Caenorhabditis elegans)
      - RUNX3 regulates WNT signaling (Caenorhabditis elegans)
        
        RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Caenorhabditis elegans)
        
        RUNX3:CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Caenorhabditis elegans)
        
        TCF/LEF:CTNNB1 [nucleoplasm] (Caenorhabditis elegans)
        
        pop-1 [nucleoplasm] (Caenorhabditis elegans)
        
        TCF/LEF:CTNNB1 [nucleoplasm] (Caenorhabditis elegans)
        
        pop-1 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q10666

Gene Names

pop-1

Reference Genes

BioGPS Gene:171849 pop-1

ENSEMBL:WBGene00004077

KEGG:cel:CELE_W10C8.2 pop-1

Monarch:171849 pop-1

NCBI Gene:171849 pop-1

UCSC:Q10666 pop-1

Wormbase:WBGene00004077

Wormbase:WBGene00004077 pop-1

Reference Transcript

RefSeq:NM_058652.3 pop-1

Other Identifiers

171849

GO:0000785

GO:0000977

GO:0000978

GO:0000981

GO:0001222

GO:0001228

GO:0001708

GO:0001709

GO:0003677

GO:0003700

GO:0003714

GO:0005515

GO:0005634

GO:0005737

GO:0006355

GO:0006357

GO:0007500

GO:0007501

GO:0008013

GO:0008356

GO:0009786

GO:0009880

GO:0010085

GO:0010628

GO:0010629

GO:0016055

GO:0019901

GO:0034514

GO:0035035

GO:0035262

GO:0040026

GO:0042659

GO:0042826

GO:0043565

GO:0045892

GO:0045893

GO:0045944

GO:0048856

GO:0051782

GO:0060070

GO:0061629

GO:0061853

GO:0160096

GO:1990907

GO:2000647

GO:2000746

Participates

as a component of

as an input of

TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Caenorhabditis elegans)

Other forms of this molecule

pop-1 [nucleoplasm]

phospho-pop-1 [nucleoplasm]

Inferred From

TCF7L2/TCF7L1 [nucleoplasm] (Homo sapiens)

TCF/LEF [nucleoplasm] (Homo sapiens)

TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Homo sapiens)

TCF7L2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_491053.4

ENSEMBL

WBGene00004077, W10C8.2.1, W10C8.2.1

PRO

Q10666

PDB

3C2G

Interactors (24)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q18825	5	bar-1 [specific granule lumen] (R-CEL-6799534-3) bar-1 [extracellular region] (R-CEL-6806309-3) bar-1 [ficolin-1-rich granule lumen] (R-CEL-6801028-3) bar-1 [cytosol] (R-CEL-201598-3) bar-1 [plasma membrane] (R-CEL-437260-3)	0.785	6
UniProt:Q9XVI2 CTNH1			0.766	6
UniProt:O17670	8	phospho-p-EYA3 [nucleoplasm] (R-CEL-5683979) phospho-p-EYA4 [nucleoplasm] (R-CEL-5683981) phospho-p-EYA1 [nucleoplasm] (R-CEL-5683951) phospho-p-EYA2 [nucleoplasm] (R-CEL-5683954) EYA1 [nucleoplasm] (R-CEL-5683625) EYA2 [nucleoplasm] (R-CEL-5683621) EYA3 [nucleoplasm] (R-CEL-5683622) EYA4 [nucleoplasm] (R-CEL-5683958)	0.712	4
UniProt:Q9NAE4 Q9NAE4			0.621	3
UniProt:O18214 MAB3			0.621	3
UniProt:Q9XVD5	1	tbx-38 [nucleoplasm] (R-CEL-8953093-10)	0.621	3
UniProt:Q18694 UN130			0.621	3
UniProt:Q10953	5	wrm-1 [specific granule lumen] (R-CEL-6799534-2) wrm-1 [extracellular region] (R-CEL-6806309-2) wrm-1 [ficolin-1-rich granule lumen] (R-CEL-6801028-2) wrm-1 [cytosol] (R-CEL-201598-2) wrm-1 [plasma membrane] (R-CEL-437260-2)	0.553	2
UniProt:P41932	5	par-5 [nucleoplasm] (R-CEL-450469) par-5 [cytosol] (R-CEL-1445105) par-5 [cytosol] (R-CEL-1445116) par-5 [cytosol] (R-CEL-48888) par-5 [cytosol] (R-CEL-380312)	0.524	2
UniProt:O17695	2	hda-1 [nucleoplasm] (R-CEL-4615958-2) hda-1 [nucleoplasm] (R-CEL-205135-2)	0.499	3
UniProt:O02482	4	unc-37 [nucleoplasm] (R-CEL-212327) unc-37 [nucleoplasm] (R-CEL-212377) unc-37 [nucleoplasm] (R-CEL-3322363) unc-37 [nucleoplasm] (R-CEL-212354)	0.499	3
UniProt:Q9NAH2	1	tbx-34 [nucleoplasm] (R-CEL-2032786-5)	0.488	2
UniProt:Q19503 HM40			0.488	2
UniProt:Q9U1R1	2	ceh-51 [nucleoplasm] (R-CEL-452586-3) ceh-51 [nucleoplasm] (R-CEL-8853887-3)	0.488	2
UniProt:O62203	2	phm-2 [nucleoplasm] (R-CEL-4085343) phm-2 [nucleoplasm] (R-CEL-4085379)	0.488	2
UniProt:G5EE68 G5EE68			0.488	2
UniProt:O17761	1	ech-8 [peroxisomal matrix] (R-CEL-400155)	0.488	2
UniProt:Q10666	6	pop-1 [nucleoplasm] (R-CEL-201923) pop-1 [nucleoplasm] (R-CEL-3214972) pop-1 [nucleoplasm] (R-CEL-5228649) pop-1 [nucleoplasm] (R-CEL-3299543) phospho-pop-1 [nucleoplasm] (R-CEL-4411392) phospho-pop-1 [nucleoplasm] (R-CEL-4411389)	0.488	2
UniProt:Q20257	1	tbx-11 [nucleoplasm] (R-CEL-8953093-5)	0.488	2
UniProt:Q20422 Q20422			0.488	2
UniProt:H2KZ82 H2KZ82			0.488	2
UniProt:Q21648 Q21648			0.488	2
UniProt:Q7JNM3 ZICH2			0.488	2
UniProt:Q94398 HM08			0.488	2

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