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DISC:procaspase-8 [plasma membrane]
Stable Identifier
R-BTA-3465443
Type
Complex
Species
Bos taurus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Bos taurus)
Apoptosis (Bos taurus)
Caspase activation via extrinsic apoptotic signalling pathway (Bos taurus)
Caspase activation via Death Receptors in the presence of ligand (Bos taurus)
Regulation by c-FLIP (Bos taurus)
Caspase-8 and FLIP(L) processing at DISC (Bos taurus)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Bos taurus)
DISC:procaspase-8 [plasma membrane] (Bos taurus)
Regulated Necrosis (Bos taurus)
RIPK1-mediated regulated necrosis (Bos taurus)
Regulation of necroptotic cell death (Bos taurus)
CASP8 activity is inhibited (Bos taurus)
FLIP(L) and procaspase-8 form heterodimer (Bos taurus)
DISC:procaspase-8 [plasma membrane] (Bos taurus)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Bos taurus)
DISC:procaspase-8 [plasma membrane] (Bos taurus)
FLIP(S) and procaspase-8 form heterodimer (Bos taurus)
DISC:procaspase-8 [plasma membrane] (Bos taurus)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Bos taurus)
DISC:procaspase-8 [plasma membrane] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CASP8 [cytosol]
(Bos taurus)
DISC [plasma membrane]
(Bos taurus)
Participates
as an input of
FLIP(L) and procaspase-8 form heterodimer (Bos taurus)
FLIP(S) and procaspase-8 form heterodimer (Bos taurus)
as a component of
DISC:procaspase-8:FLIP(L) [plasma membrane] (Bos taurus)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Bos taurus)
Inferred From
DISC:procaspase-8 [plasma membrane]
(Homo sapiens)
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