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JAK1,2 inhibitors [cytosol]
Stable Identifier
R-ALL-9678984
Type
Set [DefinedSet]
Compartment
cytosol
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Interferon Signaling (Bos taurus)
Interferon alpha/beta signaling (Bos taurus)
IFN alpha/beta binds to IFNAR2 (Bos taurus)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Bos taurus)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Bos taurus)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Bos taurus)
JAK1,2 inhibitors [cytosol]
Interferon gamma signaling (Bos taurus)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Bos taurus)
JAK1,2 inhibitors [cytosol]
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Bos taurus)
JAK1,2 inhibitors [cytosol]
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Interferon Signaling (Canis familiaris)
Interferon alpha/beta signaling (Canis familiaris)
IFN alpha/beta binds to IFNAR2 (Canis familiaris)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Canis familiaris)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Canis familiaris)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Canis familiaris)
JAK1,2 inhibitors [cytosol]
Interferon gamma signaling (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Canis familiaris)
JAK1,2 inhibitors [cytosol]
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Canis familiaris)
JAK1,2 inhibitors [cytosol]
Immune System (Danio rerio)
Cytokine Signaling in Immune system (Danio rerio)
Interferon Signaling (Danio rerio)
Interferon gamma signaling (Danio rerio)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Danio rerio)
JAK1,2 inhibitors [cytosol]
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Danio rerio)
JAK1,2 inhibitors [cytosol]
Immune System (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Interferon Signaling (Gallus gallus)
Interferon alpha/beta signaling (Gallus gallus)
IFN alpha/beta binds to IFNAR2 (Gallus gallus)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Gallus gallus)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Gallus gallus)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Gallus gallus)
JAK1,2 inhibitors [cytosol]
Interferon gamma signaling (Gallus gallus)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Gallus gallus)
JAK1,2 inhibitors [cytosol]
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Gallus gallus)
JAK1,2 inhibitors [cytosol]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
Potential therapeutics for SARS (Homo sapiens)
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Homo sapiens)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Homo sapiens)
JAK1,2 inhibitors [cytosol]
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Homo sapiens)
JAK1,2 inhibitors [cytosol]
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Homo sapiens)
JAK1,2 inhibitors [cytosol]
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Interferon alpha/beta signaling (Homo sapiens)
IFN alpha/beta binds to IFNAR2 (Homo sapiens)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Homo sapiens)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Homo sapiens)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Homo sapiens)
JAK1,2 inhibitors [cytosol]
Interferon gamma signaling (Homo sapiens)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Homo sapiens)
JAK1,2 inhibitors [cytosol]
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Homo sapiens)
JAK1,2 inhibitors [cytosol]
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Interferon Signaling (Mus musculus)
Interferon alpha/beta signaling (Mus musculus)
IFN alpha/beta binds to IFNAR2 (Mus musculus)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Mus musculus)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Mus musculus)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Mus musculus)
JAK1,2 inhibitors [cytosol]
Interferon gamma signaling (Mus musculus)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Mus musculus)
JAK1,2 inhibitors [cytosol]
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Mus musculus)
JAK1,2 inhibitors [cytosol]
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Interferon Signaling (Rattus norvegicus)
Interferon alpha/beta signaling (Rattus norvegicus)
IFN alpha/beta binds to IFNAR2 (Rattus norvegicus)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Rattus norvegicus)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Rattus norvegicus)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Rattus norvegicus)
JAK1,2 inhibitors [cytosol]
Interferon gamma signaling (Rattus norvegicus)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Rattus norvegicus)
JAK1,2 inhibitors [cytosol]
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Rattus norvegicus)
JAK1,2 inhibitors [cytosol]
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Interferon Signaling (Sus scrofa)
Interferon alpha/beta signaling (Sus scrofa)
IFN alpha/beta binds to IFNAR2 (Sus scrofa)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Sus scrofa)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Sus scrofa)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Sus scrofa)
JAK1,2 inhibitors [cytosol]
Interferon gamma signaling (Sus scrofa)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Sus scrofa)
JAK1,2 inhibitors [cytosol]
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Sus scrofa)
JAK1,2 inhibitors [cytosol]
Immune System (Xenopus tropicalis)
Cytokine Signaling in Immune system (Xenopus tropicalis)
Interferon Signaling (Xenopus tropicalis)
Interferon alpha/beta signaling (Xenopus tropicalis)
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Xenopus tropicalis)
JAK1,2 inhibitors [cytosol]
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Xenopus tropicalis)
JAK1,2 inhibitors [cytosol]
Interferon gamma signaling (Xenopus tropicalis)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Xenopus tropicalis)
JAK1,2 inhibitors [cytosol]
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Xenopus tropicalis)
JAK1,2 inhibitors [cytosol]
Participants
members
baricitinib [cytosol]
ruxolitinib [cytosol]
tofacitinib [cytosol]
delgocitinib [cytosol]
Participates
as an input of
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Gallus gallus)
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Xenopus tropicalis)
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Sus scrofa)
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Bos taurus)
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Canis familiaris)
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Mus musculus)
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Homo sapiens)
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Rattus norvegicus)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Gallus gallus)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Xenopus tropicalis)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Danio rerio)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Sus scrofa)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Bos taurus)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Rattus norvegicus)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Homo sapiens)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Mus musculus)
as a component of
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Sus scrofa)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Xenopus tropicalis)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Mus musculus)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Gallus gallus)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Rattus norvegicus)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Bos taurus)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Homo sapiens)
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Gallus gallus)
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Sus scrofa)
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Rattus norvegicus)
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Bos taurus)
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Danio rerio)
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Xenopus tropicalis)
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Homo sapiens)
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Mus musculus)
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