32511913 |
Discovery of a Janus Kinase Inhibitor Bearing a Highly Three-Dimensional Spiro Scaffold: JTE-052 (Delgocitinib) as a New Dermatological Agent to Treat Inflammatory Skin Disorders
Doi, S,
Shiozaki, M,
Orita, T,
Yamamoto, H,
Hase, Y,
Hara, Y,
Yamanaka, H,
Ogawa, Y,
Oki, C,
Noji, S,
Obika, S,
Maeda, K,
Kimoto, Y,
Hashimoto, H,
Negoro, T,
Adachi, T,
Inoue, M,
Miura, T,
Hori, A,
Tanimoto, A
|
J Med Chem |
2020 |
20130243 |
Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms
Li, J,
Quintás-Cardama, A,
Rupar, M,
Manshouri, T,
Kantarjian, H,
Burn, T,
Wen, X,
Lo, Y,
Liu, P,
Verstovsek, S,
Covington, M,
Scherle, PA,
Kelley, J,
Waeltz, P,
Caulder, E,
Shepard, S,
Vaddi, K,
Fridman, JS,
Haley, P,
Li, Y,
Rodgers, JD
|
Blood |
2010 |
20363976 |
Selective inhibition of JAK1 and JAK2 is efficacious in rodent models of arthritis: preclinical characterization of INCB028050
Favata, MF,
Shi, J,
Yeleswaram, S,
Li, J,
Metcalf, B,
Wen, X,
Scherle, PA,
Thomas, B,
McGee, R,
Collins, R,
Newton, RC,
Burn, TC,
Covington, MB,
Friedman, SM,
Shepard, S,
Haley, PJ,
Vaddi, K,
Hollis, G,
Fridman, JS,
Li, Y,
Rodgers, JD,
Collier, P
|
J. Immunol. |
2010 |