Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
ISCIT [mitochondrial matrix]
Stable Identifier
R-ALL-29938
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
Isocitrate, D-threo-isocitric acid, (1R,2S)-1-Hydroxypropane-1,2,3-tricarboxylate, Isocitric acid, 1-Hydroxytricarballylic acid, 1-Hydroxypropane-1,2,3-tricarboxylic acid, D-erythro-Isocitric acid
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Citric acid cycle (TCA cycle) (Bos taurus)
ACO2 isomerizes citrate (Bos taurus)
ISCIT [mitochondrial matrix]
IDH2 dimer decarboxylates isocitrate (Bos taurus)
ISCIT [mitochondrial matrix]
IDH3 complex decarboxylates isocitrate (Bos taurus)
ISCIT [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Aerobic respiration and respiratory electron transport (Caenorhabditis elegans)
Citric acid cycle (TCA cycle) (Caenorhabditis elegans)
ACO2 isomerizes citrate (Caenorhabditis elegans)
ISCIT [mitochondrial matrix]
IDH2 dimer decarboxylates isocitrate (Caenorhabditis elegans)
ISCIT [mitochondrial matrix]
IDH3 complex decarboxylates isocitrate (Caenorhabditis elegans)
ISCIT [mitochondrial matrix]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Citric acid cycle (TCA cycle) (Canis familiaris)
ACO2 isomerizes citrate (Canis familiaris)
ISCIT [mitochondrial matrix]
IDH2 dimer decarboxylates isocitrate (Canis familiaris)
ISCIT [mitochondrial matrix]
IDH3 complex decarboxylates isocitrate (Canis familiaris)
ISCIT [mitochondrial matrix]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Citric acid cycle (TCA cycle) (Danio rerio)
ACO2 isomerizes citrate (Danio rerio)
ISCIT [mitochondrial matrix]
IDH2 dimer decarboxylates isocitrate (Danio rerio)
ISCIT [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Aerobic respiration and respiratory electron transport (Dictyostelium discoideum)
Citric acid cycle (TCA cycle) (Dictyostelium discoideum)
ACO2 isomerizes citrate (Dictyostelium discoideum)
ISCIT [mitochondrial matrix]
IDH3 complex decarboxylates isocitrate (Dictyostelium discoideum)
ISCIT [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Citric acid cycle (TCA cycle) (Drosophila melanogaster)
ACO2 isomerizes citrate (Drosophila melanogaster)
ISCIT [mitochondrial matrix]
IDH3 complex decarboxylates isocitrate (Drosophila melanogaster)
ISCIT [mitochondrial matrix]
Metabolism (Gallus gallus)
The tricarboxylic acid cycle (Gallus gallus)
citrate <=> isocitrate (Gallus gallus)
ISCIT [mitochondrial matrix]
isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+ (Gallus gallus)
ISCIT [mitochondrial matrix]
isocitrate <=> citrate (Gallus gallus)
ISCIT [mitochondrial matrix]
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Citric acid cycle (TCA cycle) (Homo sapiens)
ACO2 isomerizes citrate (Homo sapiens)
ISCIT [mitochondrial matrix]
IDH2 dimer decarboxylates isocitrate (Homo sapiens)
ISCIT [mitochondrial matrix]
IDH3 complex decarboxylates isocitrate (Homo sapiens)
ISCIT [mitochondrial matrix]
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Citric acid cycle (TCA cycle) (Mus musculus)
ACO2 isomerizes citrate (Mus musculus)
ISCIT [mitochondrial matrix]
IDH2 dimer decarboxylates isocitrate (Mus musculus)
ISCIT [mitochondrial matrix]
IDH3 complex decarboxylates isocitrate (Mus musculus)
ISCIT [mitochondrial matrix]
Metabolism (Plasmodium falciparum)
Aerobic respiration and respiratory electron transport (Plasmodium falciparum)
Citric acid cycle (TCA cycle) (Plasmodium falciparum)
IDH2 dimer decarboxylates isocitrate (Plasmodium falciparum)
ISCIT [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Aerobic respiration and respiratory electron transport (Rattus norvegicus)
Citric acid cycle (TCA cycle) (Rattus norvegicus)
ACO2 isomerizes citrate (Rattus norvegicus)
ISCIT [mitochondrial matrix]
IDH2 dimer decarboxylates isocitrate (Rattus norvegicus)
ISCIT [mitochondrial matrix]
IDH3 complex decarboxylates isocitrate (Rattus norvegicus)
ISCIT [mitochondrial matrix]
Metabolism (Saccharomyces cerevisiae)
Aerobic respiration and respiratory electron transport (Saccharomyces cerevisiae)
Citric acid cycle (TCA cycle) (Saccharomyces cerevisiae)
ACO2 isomerizes citrate (Saccharomyces cerevisiae)
ISCIT [mitochondrial matrix]
IDH3 complex decarboxylates isocitrate (Saccharomyces cerevisiae)
ISCIT [mitochondrial matrix]
Metabolism (Schizosaccharomyces pombe)
Aerobic respiration and respiratory electron transport (Schizosaccharomyces pombe)
Citric acid cycle (TCA cycle) (Schizosaccharomyces pombe)
ACO2 isomerizes citrate (Schizosaccharomyces pombe)
ISCIT [mitochondrial matrix]
IDH3 complex decarboxylates isocitrate (Schizosaccharomyces pombe)
ISCIT [mitochondrial matrix]
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Citric acid cycle (TCA cycle) (Sus scrofa)
ACO2 isomerizes citrate (Sus scrofa)
ISCIT [mitochondrial matrix]
IDH2 dimer decarboxylates isocitrate (Sus scrofa)
ISCIT [mitochondrial matrix]
IDH3 complex decarboxylates isocitrate (Sus scrofa)
ISCIT [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Aerobic respiration and respiratory electron transport (Xenopus tropicalis)
Citric acid cycle (TCA cycle) (Xenopus tropicalis)
ACO2 isomerizes citrate (Xenopus tropicalis)
ISCIT [mitochondrial matrix]
IDH2 dimer decarboxylates isocitrate (Xenopus tropicalis)
ISCIT [mitochondrial matrix]
External Reference Information
External Reference
D-threo-isocitrate(3-) [ChEBI:15562]
Participates
as an output of
citrate <=> isocitrate (Gallus gallus)
ACO2 isomerizes citrate (Xenopus tropicalis)
ACO2 isomerizes citrate (Saccharomyces cerevisiae)
ACO2 isomerizes citrate (Dictyostelium discoideum)
ACO2 isomerizes citrate (Schizosaccharomyces pombe)
ACO2 isomerizes citrate (Caenorhabditis elegans)
ACO2 isomerizes citrate (Drosophila melanogaster)
ACO2 isomerizes citrate (Gallus gallus)
ACO2 isomerizes citrate (Danio rerio)
ACO2 isomerizes citrate (Sus scrofa)
ACO2 isomerizes citrate (Mus musculus)
ACO2 isomerizes citrate (Bos taurus)
ACO2 isomerizes citrate (Homo sapiens)
ACO2 isomerizes citrate (Canis familiaris)
ACO2 isomerizes citrate (Rattus norvegicus)
as an input of
isocitrate <=> citrate (Gallus gallus)
isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+ (Gallus gallus)
IDH3 complex decarboxylates isocitrate (Canis familiaris)
IDH3 complex decarboxylates isocitrate (Bos taurus)
IDH2 dimer decarboxylates isocitrate (Rattus norvegicus)
IDH3 complex decarboxylates isocitrate (Mus musculus)
IDH2 dimer decarboxylates isocitrate (Sus scrofa)
IDH2 dimer decarboxylates isocitrate (Xenopus tropicalis)
IDH2 dimer decarboxylates isocitrate (Plasmodium falciparum)
IDH3 complex decarboxylates isocitrate (Saccharomyces cerevisiae)
IDH3 complex decarboxylates isocitrate (Dictyostelium discoideum)
IDH3 complex decarboxylates isocitrate (Schizosaccharomyces pombe)
IDH3 complex decarboxylates isocitrate (Caenorhabditis elegans)
IDH2 dimer decarboxylates isocitrate (Caenorhabditis elegans)
IDH3 complex decarboxylates isocitrate (Drosophila melanogaster)
IDH2 dimer decarboxylates isocitrate (Gallus gallus)
IDH2 dimer decarboxylates isocitrate (Danio rerio)
IDH3 complex decarboxylates isocitrate (Sus scrofa)
IDH2 dimer decarboxylates isocitrate (Mus musculus)
IDH2 dimer decarboxylates isocitrate (Homo sapiens)
IDH2 dimer decarboxylates isocitrate (Bos taurus)
IDH3 complex decarboxylates isocitrate (Homo sapiens)
IDH2 dimer decarboxylates isocitrate (Canis familiaris)
IDH3 complex decarboxylates isocitrate (Rattus norvegicus)
Other forms of this molecule
ISCIT [cytosol]
ISCIT [peroxisomal matrix]
Cross References
KNApSAcK
C00001188
AraCyc
THREO-DS-ISO-CITRATE
CAS
30810-51-6
,
320-77-4
COMPOUND
C00311
,
C00451
PubChem Compound
5459771
ZINC
000000895179
KEGG Gene
C00451
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text