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LAN [endoplasmic reticulum membrane]
Stable Identifier
R-ALL-194634
Type
Chemical Compound [SimpleEntity]
Compartment
endoplasmic reticulum membrane
Synonyms
LNSOL, lanosterol
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Cytochrome P450 - arranged by substrate type (Bos taurus)
Endogenous sterols (Bos taurus)
CYP51A1 demethylates LAN (Bos taurus)
LAN [endoplasmic reticulum membrane]
Metabolism of lipids (Bos taurus)
Metabolism of steroids (Bos taurus)
Cholesterol biosynthesis (Bos taurus)
Cholesterol biosynthesis via desmosterol (Bloch pathway) (Bos taurus)
CYP51A1 demethylates LAN (Bos taurus)
LAN [endoplasmic reticulum membrane]
Lanosterol biosynthesis (Bos taurus)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Bos taurus)
LAN [endoplasmic reticulum membrane]
Zymostenol biosynthesis via lathosterol (Kandutsch-Russell pathway) (Bos taurus)
DHCR24 reduces LAN to 24,25-dhLAN (Bos taurus)
LAN [endoplasmic reticulum membrane]
Metabolism (Caenorhabditis elegans)
Metabolism of lipids (Caenorhabditis elegans)
Metabolism of steroids (Caenorhabditis elegans)
Cholesterol biosynthesis (Caenorhabditis elegans)
Zymostenol biosynthesis via lathosterol (Kandutsch-Russell pathway) (Caenorhabditis elegans)
DHCR24 reduces LAN to 24,25-dhLAN (Caenorhabditis elegans)
LAN [endoplasmic reticulum membrane]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Cytochrome P450 - arranged by substrate type (Canis familiaris)
Endogenous sterols (Canis familiaris)
CYP51A1 demethylates LAN (Canis familiaris)
LAN [endoplasmic reticulum membrane]
Metabolism of lipids (Canis familiaris)
Metabolism of steroids (Canis familiaris)
Cholesterol biosynthesis (Canis familiaris)
Cholesterol biosynthesis via desmosterol (Bloch pathway) (Canis familiaris)
CYP51A1 demethylates LAN (Canis familiaris)
LAN [endoplasmic reticulum membrane]
Lanosterol biosynthesis (Canis familiaris)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Canis familiaris)
LAN [endoplasmic reticulum membrane]
Zymostenol biosynthesis via lathosterol (Kandutsch-Russell pathway) (Canis familiaris)
DHCR24 reduces LAN to 24,25-dhLAN (Canis familiaris)
LAN [endoplasmic reticulum membrane]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase I - Functionalization of compounds (Danio rerio)
Cytochrome P450 - arranged by substrate type (Danio rerio)
Endogenous sterols (Danio rerio)
CYP51A1 demethylates LAN (Danio rerio)
LAN [endoplasmic reticulum membrane]
Metabolism of lipids (Danio rerio)
Metabolism of steroids (Danio rerio)
Cholesterol biosynthesis (Danio rerio)
Cholesterol biosynthesis via desmosterol (Bloch pathway) (Danio rerio)
CYP51A1 demethylates LAN (Danio rerio)
LAN [endoplasmic reticulum membrane]
Lanosterol biosynthesis (Danio rerio)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Danio rerio)
LAN [endoplasmic reticulum membrane]
Zymostenol biosynthesis via lathosterol (Kandutsch-Russell pathway) (Danio rerio)
DHCR24 reduces LAN to 24,25-dhLAN (Danio rerio)
LAN [endoplasmic reticulum membrane]
Metabolism (Dictyostelium discoideum)
Biological oxidations (Dictyostelium discoideum)
Phase I - Functionalization of compounds (Dictyostelium discoideum)
Cytochrome P450 - arranged by substrate type (Dictyostelium discoideum)
Endogenous sterols (Dictyostelium discoideum)
CYP51A1 demethylates LAN (Dictyostelium discoideum)
LAN [endoplasmic reticulum membrane]
Metabolism of lipids (Dictyostelium discoideum)
Metabolism of steroids (Dictyostelium discoideum)
Cholesterol biosynthesis (Dictyostelium discoideum)
Cholesterol biosynthesis via desmosterol (Bloch pathway) (Dictyostelium discoideum)
CYP51A1 demethylates LAN (Dictyostelium discoideum)
LAN [endoplasmic reticulum membrane]
Lanosterol biosynthesis (Dictyostelium discoideum)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Dictyostelium discoideum)
LAN [endoplasmic reticulum membrane]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
Cytochrome P450 - arranged by substrate type (Gallus gallus)
Endogenous sterols (Gallus gallus)
CYP51A1 demethylates LAN (Gallus gallus)
LAN [endoplasmic reticulum membrane]
Metabolism of lipids (Gallus gallus)
Metabolism of steroids (Gallus gallus)
Cholesterol biosynthesis (Gallus gallus)
Cholesterol biosynthesis via desmosterol (Bloch pathway) (Gallus gallus)
CYP51A1 demethylates LAN (Gallus gallus)
LAN [endoplasmic reticulum membrane]
Lanosterol biosynthesis (Gallus gallus)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Gallus gallus)
LAN [endoplasmic reticulum membrane]
Zymostenol biosynthesis via lathosterol (Kandutsch-Russell pathway) (Gallus gallus)
DHCR24 reduces LAN to 24,25-dhLAN (Gallus gallus)
LAN [endoplasmic reticulum membrane]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Cytochrome P450 - arranged by substrate type (Homo sapiens)
Endogenous sterols (Homo sapiens)
CYP51A1 demethylates LAN (Homo sapiens)
LAN [endoplasmic reticulum membrane]
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Cholesterol biosynthesis (Homo sapiens)
Cholesterol biosynthesis via desmosterol (Bloch pathway) (Homo sapiens)
CYP51A1 demethylates LAN (Homo sapiens)
LAN [endoplasmic reticulum membrane]
Lanosterol biosynthesis (Homo sapiens)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Homo sapiens)
LAN [endoplasmic reticulum membrane]
Zymostenol biosynthesis via lathosterol (Kandutsch-Russell pathway) (Homo sapiens)
DHCR24 reduces LAN to 24,25-dhLAN (Homo sapiens)
LAN [endoplasmic reticulum membrane]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Cytochrome P450 - arranged by substrate type (Mus musculus)
Endogenous sterols (Mus musculus)
CYP51A1 demethylates LAN (Mus musculus)
LAN [endoplasmic reticulum membrane]
Metabolism of lipids (Mus musculus)
Metabolism of steroids (Mus musculus)
Cholesterol biosynthesis (Mus musculus)
Cholesterol biosynthesis via desmosterol (Bloch pathway) (Mus musculus)
CYP51A1 demethylates LAN (Mus musculus)
LAN [endoplasmic reticulum membrane]
Lanosterol biosynthesis (Mus musculus)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Mus musculus)
LAN [endoplasmic reticulum membrane]
Zymostenol biosynthesis via lathosterol (Kandutsch-Russell pathway) (Mus musculus)
DHCR24 reduces LAN to 24,25-dhLAN (Mus musculus)
LAN [endoplasmic reticulum membrane]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Cytochrome P450 - arranged by substrate type (Rattus norvegicus)
Endogenous sterols (Rattus norvegicus)
CYP51A1 demethylates LAN (Rattus norvegicus)
LAN [endoplasmic reticulum membrane]
Metabolism of lipids (Rattus norvegicus)
Metabolism of steroids (Rattus norvegicus)
Cholesterol biosynthesis (Rattus norvegicus)
Cholesterol biosynthesis via desmosterol (Bloch pathway) (Rattus norvegicus)
CYP51A1 demethylates LAN (Rattus norvegicus)
LAN [endoplasmic reticulum membrane]
Lanosterol biosynthesis (Rattus norvegicus)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Rattus norvegicus)
LAN [endoplasmic reticulum membrane]
Zymostenol biosynthesis via lathosterol (Kandutsch-Russell pathway) (Rattus norvegicus)
DHCR24 reduces LAN to 24,25-dhLAN (Rattus norvegicus)
LAN [endoplasmic reticulum membrane]
Metabolism (Saccharomyces cerevisiae)
Biological oxidations (Saccharomyces cerevisiae)
Phase I - Functionalization of compounds (Saccharomyces cerevisiae)
Cytochrome P450 - arranged by substrate type (Saccharomyces cerevisiae)
Endogenous sterols (Saccharomyces cerevisiae)
CYP51A1 demethylates LAN (Saccharomyces cerevisiae)
LAN [endoplasmic reticulum membrane]
Metabolism of lipids (Saccharomyces cerevisiae)
Metabolism of steroids (Saccharomyces cerevisiae)
Cholesterol biosynthesis (Saccharomyces cerevisiae)
Cholesterol biosynthesis via desmosterol (Bloch pathway) (Saccharomyces cerevisiae)
CYP51A1 demethylates LAN (Saccharomyces cerevisiae)
LAN [endoplasmic reticulum membrane]
Lanosterol biosynthesis (Saccharomyces cerevisiae)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Saccharomyces cerevisiae)
LAN [endoplasmic reticulum membrane]
Metabolism (Schizosaccharomyces pombe)
Biological oxidations (Schizosaccharomyces pombe)
Phase I - Functionalization of compounds (Schizosaccharomyces pombe)
Cytochrome P450 - arranged by substrate type (Schizosaccharomyces pombe)
Endogenous sterols (Schizosaccharomyces pombe)
CYP51A1 demethylates LAN (Schizosaccharomyces pombe)
LAN [endoplasmic reticulum membrane]
Metabolism of lipids (Schizosaccharomyces pombe)
Metabolism of steroids (Schizosaccharomyces pombe)
Cholesterol biosynthesis (Schizosaccharomyces pombe)
Cholesterol biosynthesis via desmosterol (Bloch pathway) (Schizosaccharomyces pombe)
CYP51A1 demethylates LAN (Schizosaccharomyces pombe)
LAN [endoplasmic reticulum membrane]
Lanosterol biosynthesis (Schizosaccharomyces pombe)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Schizosaccharomyces pombe)
LAN [endoplasmic reticulum membrane]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
Cytochrome P450 - arranged by substrate type (Sus scrofa)
Endogenous sterols (Sus scrofa)
CYP51A1 demethylates LAN (Sus scrofa)
LAN [endoplasmic reticulum membrane]
Metabolism of lipids (Sus scrofa)
Metabolism of steroids (Sus scrofa)
Cholesterol biosynthesis (Sus scrofa)
Cholesterol biosynthesis via desmosterol (Bloch pathway) (Sus scrofa)
CYP51A1 demethylates LAN (Sus scrofa)
LAN [endoplasmic reticulum membrane]
Lanosterol biosynthesis (Sus scrofa)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Sus scrofa)
LAN [endoplasmic reticulum membrane]
Zymostenol biosynthesis via lathosterol (Kandutsch-Russell pathway) (Sus scrofa)
DHCR24 reduces LAN to 24,25-dhLAN (Sus scrofa)
LAN [endoplasmic reticulum membrane]
Metabolism (Xenopus tropicalis)
Metabolism of lipids (Xenopus tropicalis)
Metabolism of steroids (Xenopus tropicalis)
Cholesterol biosynthesis (Xenopus tropicalis)
Lanosterol biosynthesis (Xenopus tropicalis)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Xenopus tropicalis)
LAN [endoplasmic reticulum membrane]
Zymostenol biosynthesis via lathosterol (Kandutsch-Russell pathway) (Xenopus tropicalis)
DHCR24 reduces LAN to 24,25-dhLAN (Xenopus tropicalis)
LAN [endoplasmic reticulum membrane]
External Reference Information
External Reference
lanosterol [ChEBI:16521]
Participates
as an input of
CYP51A1 demethylates LAN (Saccharomyces cerevisiae)
CYP51A1 demethylates LAN (Schizosaccharomyces pombe)
CYP51A1 demethylates LAN (Dictyostelium discoideum)
CYP51A1 demethylates LAN (Gallus gallus)
CYP51A1 demethylates LAN (Danio rerio)
CYP51A1 demethylates LAN (Sus scrofa)
CYP51A1 demethylates LAN (Bos taurus)
CYP51A1 demethylates LAN (Canis familiaris)
CYP51A1 demethylates LAN (Rattus norvegicus)
CYP51A1 demethylates LAN (Mus musculus)
CYP51A1 demethylates LAN (Homo sapiens)
DHCR24 reduces LAN to 24,25-dhLAN (Caenorhabditis elegans)
DHCR24 reduces LAN to 24,25-dhLAN (Gallus gallus)
DHCR24 reduces LAN to 24,25-dhLAN (Xenopus tropicalis)
DHCR24 reduces LAN to 24,25-dhLAN (Danio rerio)
DHCR24 reduces LAN to 24,25-dhLAN (Sus scrofa)
DHCR24 reduces LAN to 24,25-dhLAN (Bos taurus)
DHCR24 reduces LAN to 24,25-dhLAN (Canis familiaris)
DHCR24 reduces LAN to 24,25-dhLAN (Rattus norvegicus)
DHCR24 reduces LAN to 24,25-dhLAN (Mus musculus)
DHCR24 reduces LAN to 24,25-dhLAN (Homo sapiens)
as an output of
Squalene 2,3-epoxide cyclizes, forming lanosterol (Saccharomyces cerevisiae)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Schizosaccharomyces pombe)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Dictyostelium discoideum)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Gallus gallus)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Xenopus tropicalis)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Danio rerio)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Sus scrofa)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Bos taurus)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Canis familiaris)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Rattus norvegicus)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Mus musculus)
Squalene 2,3-epoxide cyclizes, forming lanosterol (Homo sapiens)
Cross References
Guide to Pharmacology - Ligands
2746
COMPOUND
C01724
HMDB Metabolite
HMDB0001251
ZINC
ZINC000003870056
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