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PI(3,5)P2 [plasma membrane]
Stable Identifier
R-ALL-1806224
Type
Chemical Compound [SimpleEntity]
Compartment
plasma membrane
Synonyms
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of lipids (Bos taurus)
Phospholipid metabolism (Bos taurus)
PI Metabolism (Bos taurus)
Synthesis of PIPs at the plasma membrane (Bos taurus)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Bos taurus)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Bos taurus)
PI(3,5)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Bos taurus)
PI(3,5)P2 [plasma membrane]
Metabolism (Caenorhabditis elegans)
Metabolism of lipids (Caenorhabditis elegans)
Phospholipid metabolism (Caenorhabditis elegans)
PI Metabolism (Caenorhabditis elegans)
Synthesis of PIPs at the plasma membrane (Caenorhabditis elegans)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Caenorhabditis elegans)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Caenorhabditis elegans)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Caenorhabditis elegans)
PI(3,5)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Caenorhabditis elegans)
PI(3,5)P2 [plasma membrane]
Metabolism (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Phospholipid metabolism (Canis familiaris)
PI Metabolism (Canis familiaris)
Synthesis of PIPs at the plasma membrane (Canis familiaris)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Canis familiaris)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Canis familiaris)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Canis familiaris)
PI(3,5)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Canis familiaris)
PI(3,5)P2 [plasma membrane]
Metabolism (Danio rerio)
Metabolism of lipids (Danio rerio)
Phospholipid metabolism (Danio rerio)
PI Metabolism (Danio rerio)
Synthesis of PIPs at the plasma membrane (Danio rerio)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Danio rerio)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Danio rerio)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Danio rerio)
PI(3,5)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Danio rerio)
PI(3,5)P2 [plasma membrane]
Metabolism (Dictyostelium discoideum)
Metabolism of lipids (Dictyostelium discoideum)
Phospholipid metabolism (Dictyostelium discoideum)
PI Metabolism (Dictyostelium discoideum)
Synthesis of PIPs at the plasma membrane (Dictyostelium discoideum)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Dictyostelium discoideum)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Dictyostelium discoideum)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Dictyostelium discoideum)
PI(3,5)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Dictyostelium discoideum)
PI(3,5)P2 [plasma membrane]
Metabolism (Drosophila melanogaster)
Metabolism of lipids (Drosophila melanogaster)
Phospholipid metabolism (Drosophila melanogaster)
PI Metabolism (Drosophila melanogaster)
Synthesis of PIPs at the plasma membrane (Drosophila melanogaster)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Drosophila melanogaster)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Drosophila melanogaster)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Drosophila melanogaster)
PI(3,5)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Drosophila melanogaster)
PI(3,5)P2 [plasma membrane]
Metabolism (Gallus gallus)
Metabolism of lipids (Gallus gallus)
Phospholipid metabolism (Gallus gallus)
PI Metabolism (Gallus gallus)
Synthesis of PIPs at the plasma membrane (Gallus gallus)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Gallus gallus)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Gallus gallus)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Gallus gallus)
PI(3,5)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Gallus gallus)
PI(3,5)P2 [plasma membrane]
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
PI Metabolism (Homo sapiens)
Synthesis of PIPs at the plasma membrane (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Homo sapiens)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Homo sapiens)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Homo sapiens)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by the MTMR2:SBF2 tetramer at the plasma membrane (Homo sapiens)
PI(3,5)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Homo sapiens)
PI(3,5)P2 [plasma membrane]
Metabolism (Mus musculus)
Metabolism of lipids (Mus musculus)
Phospholipid metabolism (Mus musculus)
PI Metabolism (Mus musculus)
Synthesis of PIPs at the plasma membrane (Mus musculus)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Mus musculus)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Mus musculus)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Mus musculus)
PI(3,5)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Mus musculus)
PI(3,5)P2 [plasma membrane]
Metabolism (Plasmodium falciparum)
Metabolism of lipids (Plasmodium falciparum)
Phospholipid metabolism (Plasmodium falciparum)
PI Metabolism (Plasmodium falciparum)
Synthesis of PIPs at the plasma membrane (Plasmodium falciparum)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Plasmodium falciparum)
PI(3,5)P2 [plasma membrane]
Metabolism (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Phospholipid metabolism (Rattus norvegicus)
PI Metabolism (Rattus norvegicus)
Synthesis of PIPs at the plasma membrane (Rattus norvegicus)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Rattus norvegicus)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Rattus norvegicus)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Rattus norvegicus)
PI(3,5)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Rattus norvegicus)
PI(3,5)P2 [plasma membrane]
Metabolism (Saccharomyces cerevisiae)
Metabolism of lipids (Saccharomyces cerevisiae)
Phospholipid metabolism (Saccharomyces cerevisiae)
PI Metabolism (Saccharomyces cerevisiae)
Synthesis of PIPs at the plasma membrane (Saccharomyces cerevisiae)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Saccharomyces cerevisiae)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Saccharomyces cerevisiae)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Saccharomyces cerevisiae)
PI(3,5)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Saccharomyces cerevisiae)
PI(3,5)P2 [plasma membrane]
Metabolism (Schizosaccharomyces pombe)
Metabolism of lipids (Schizosaccharomyces pombe)
Phospholipid metabolism (Schizosaccharomyces pombe)
PI Metabolism (Schizosaccharomyces pombe)
Synthesis of PIPs at the plasma membrane (Schizosaccharomyces pombe)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Schizosaccharomyces pombe)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Schizosaccharomyces pombe)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Schizosaccharomyces pombe)
PI(3,5)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Schizosaccharomyces pombe)
PI(3,5)P2 [plasma membrane]
Metabolism (Sus scrofa)
Metabolism of lipids (Sus scrofa)
Phospholipid metabolism (Sus scrofa)
PI Metabolism (Sus scrofa)
Synthesis of PIPs at the plasma membrane (Sus scrofa)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Sus scrofa)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Sus scrofa)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Sus scrofa)
PI(3,5)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Sus scrofa)
PI(3,5)P2 [plasma membrane]
Metabolism (Xenopus tropicalis)
Metabolism of lipids (Xenopus tropicalis)
Phospholipid metabolism (Xenopus tropicalis)
PI Metabolism (Xenopus tropicalis)
Synthesis of PIPs at the plasma membrane (Xenopus tropicalis)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Xenopus tropicalis)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Xenopus tropicalis)
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Xenopus tropicalis)
PI(3,5)P2 [plasma membrane]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Xenopus tropicalis)
PI(3,5)P2 [plasma membrane]
External Reference Information
External Reference
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate(5-) [ChEBI:57923]
Participates
as an input of
PI(3,5)P2 is dephosphorylated to PI5P by the Mtmr2:Sbf2 tetramer at the plasma membrane (Mus musculus)
PI(3,5)P2 is dephosphorylated to PI5P by the MTMR2:SBF2 tetramer at the plasma membrane (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Saccharomyces cerevisiae)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Schizosaccharomyces pombe)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Dictyostelium discoideum)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Caenorhabditis elegans)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Drosophila melanogaster)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Gallus gallus)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Xenopus tropicalis)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Danio rerio)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Sus scrofa)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Bos taurus)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Mus musculus)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Rattus norvegicus)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Canis familiaris)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Canis familiaris)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Sus scrofa)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Sus scrofa)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Bos taurus)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Danio rerio)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Danio rerio)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Xenopus tropicalis)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Xenopus tropicalis)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Gallus gallus)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Gallus gallus)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Drosophila melanogaster)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Drosophila melanogaster)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Caenorhabditis elegans)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Caenorhabditis elegans)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Dictyostelium discoideum)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Dictyostelium discoideum)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Schizosaccharomyces pombe)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Schizosaccharomyces pombe)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Saccharomyces cerevisiae)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Saccharomyces cerevisiae)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Rattus norvegicus)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Mus musculus)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Mus musculus)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Rattus norvegicus)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Canis familiaris)
as an output of
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Homo sapiens)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Mus musculus)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Rattus norvegicus)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Canis familiaris)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Sus scrofa)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Bos taurus)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Danio rerio)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Xenopus tropicalis)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Gallus gallus)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Drosophila melanogaster)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Caenorhabditis elegans)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Dictyostelium discoideum)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Schizosaccharomyces pombe)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Saccharomyces cerevisiae)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Plasmodium falciparum)
Other forms of this molecule
PI(3,5)P2 [lysosomal membrane]
PI(3,5)P2 [endoplasmic reticulum membrane]
PI(3,5)P2 [late endosome membrane]
PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 [Golgi membrane]
PI(3,5)P2 [phagophore assembly site membrane]
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