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What is Reactome ?
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Digital Preservation
Contact us
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Docs
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How do I search ?
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Fe2+ [phagocytic vesicle lumen]
Stable Identifier
R-ALL-1222286
Type
Chemical Compound [SimpleEntity]
Compartment
phagocytic vesicle lumen
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Immune System (Bos taurus)
Innate Immune System (Bos taurus)
Antimicrobial peptides (Bos taurus)
Ion influx/efflux at host-pathogen interface (Bos taurus)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Bos taurus)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
ROS and RNS production in phagocytes (Bos taurus)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Bos taurus)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of bile salts and organic acids, metal ions and amine compounds (Bos taurus)
Metal ion SLC transporters (Bos taurus)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Bos taurus)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Immune System (Caenorhabditis elegans)
Innate Immune System (Caenorhabditis elegans)
Antimicrobial peptides (Caenorhabditis elegans)
Ion influx/efflux at host-pathogen interface (Caenorhabditis elegans)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Caenorhabditis elegans)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
ROS and RNS production in phagocytes (Caenorhabditis elegans)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Caenorhabditis elegans)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of bile salts and organic acids, metal ions and amine compounds (Caenorhabditis elegans)
Metal ion SLC transporters (Caenorhabditis elegans)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Caenorhabditis elegans)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Immune System (Canis familiaris)
Innate Immune System (Canis familiaris)
Antimicrobial peptides (Canis familiaris)
Ion influx/efflux at host-pathogen interface (Canis familiaris)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Canis familiaris)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
ROS and RNS production in phagocytes (Canis familiaris)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Canis familiaris)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of bile salts and organic acids, metal ions and amine compounds (Canis familiaris)
Metal ion SLC transporters (Canis familiaris)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Canis familiaris)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Immune System (Danio rerio)
Innate Immune System (Danio rerio)
Antimicrobial peptides (Danio rerio)
Ion influx/efflux at host-pathogen interface (Danio rerio)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Danio rerio)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
ROS and RNS production in phagocytes (Danio rerio)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Danio rerio)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
Transport of bile salts and organic acids, metal ions and amine compounds (Danio rerio)
Metal ion SLC transporters (Danio rerio)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Danio rerio)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Immune System (Dictyostelium discoideum)
Innate Immune System (Dictyostelium discoideum)
Antimicrobial peptides (Dictyostelium discoideum)
Ion influx/efflux at host-pathogen interface (Dictyostelium discoideum)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Dictyostelium discoideum)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
ROS and RNS production in phagocytes (Dictyostelium discoideum)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Dictyostelium discoideum)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Transport of small molecules (Dictyostelium discoideum)
SLC-mediated transmembrane transport (Dictyostelium discoideum)
Transport of bile salts and organic acids, metal ions and amine compounds (Dictyostelium discoideum)
Metal ion SLC transporters (Dictyostelium discoideum)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Dictyostelium discoideum)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Immune System (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Antimicrobial peptides (Drosophila melanogaster)
Ion influx/efflux at host-pathogen interface (Drosophila melanogaster)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Drosophila melanogaster)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
ROS and RNS production in phagocytes (Drosophila melanogaster)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Drosophila melanogaster)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of bile salts and organic acids, metal ions and amine compounds (Drosophila melanogaster)
Metal ion SLC transporters (Drosophila melanogaster)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Drosophila melanogaster)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Immune System (Gallus gallus)
Innate Immune System (Gallus gallus)
Antimicrobial peptides (Gallus gallus)
Ion influx/efflux at host-pathogen interface (Gallus gallus)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Gallus gallus)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
ROS and RNS production in phagocytes (Gallus gallus)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Gallus gallus)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of bile salts and organic acids, metal ions and amine compounds (Gallus gallus)
Metal ion SLC transporters (Gallus gallus)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Gallus gallus)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Antimicrobial peptides (Homo sapiens)
Ion influx/efflux at host-pathogen interface (Homo sapiens)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Homo sapiens)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
ROS and RNS production in phagocytes (Homo sapiens)
Events associated with phagocytolytic activity of PMN cells (Homo sapiens)
HOCl-induced glycosaminoglycan fragmentation (Homo sapiens)
Fe2+ [phagocytic vesicle lumen]
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Homo sapiens)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Metal ion SLC transporters (Homo sapiens)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Homo sapiens)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Immune System (Mus musculus)
Innate Immune System (Mus musculus)
Antimicrobial peptides (Mus musculus)
Ion influx/efflux at host-pathogen interface (Mus musculus)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Mus musculus)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
ROS and RNS production in phagocytes (Mus musculus)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Mus musculus)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of bile salts and organic acids, metal ions and amine compounds (Mus musculus)
Metal ion SLC transporters (Mus musculus)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Mus musculus)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Immune System (Plasmodium falciparum)
Innate Immune System (Plasmodium falciparum)
Antimicrobial peptides (Plasmodium falciparum)
Ion influx/efflux at host-pathogen interface (Plasmodium falciparum)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Plasmodium falciparum)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
ROS and RNS production in phagocytes (Plasmodium falciparum)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Plasmodium falciparum)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Transport of small molecules (Plasmodium falciparum)
SLC-mediated transmembrane transport (Plasmodium falciparum)
Transport of bile salts and organic acids, metal ions and amine compounds (Plasmodium falciparum)
Metal ion SLC transporters (Plasmodium falciparum)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Plasmodium falciparum)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Immune System (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Antimicrobial peptides (Rattus norvegicus)
Ion influx/efflux at host-pathogen interface (Rattus norvegicus)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Rattus norvegicus)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
ROS and RNS production in phagocytes (Rattus norvegicus)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Rattus norvegicus)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of bile salts and organic acids, metal ions and amine compounds (Rattus norvegicus)
Metal ion SLC transporters (Rattus norvegicus)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Rattus norvegicus)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Immune System (Sus scrofa)
Innate Immune System (Sus scrofa)
Antimicrobial peptides (Sus scrofa)
Ion influx/efflux at host-pathogen interface (Sus scrofa)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Sus scrofa)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
ROS and RNS production in phagocytes (Sus scrofa)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Sus scrofa)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of bile salts and organic acids, metal ions and amine compounds (Sus scrofa)
Metal ion SLC transporters (Sus scrofa)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Sus scrofa)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Immune System (Xenopus tropicalis)
Innate Immune System (Xenopus tropicalis)
Antimicrobial peptides (Xenopus tropicalis)
Ion influx/efflux at host-pathogen interface (Xenopus tropicalis)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Xenopus tropicalis)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
ROS and RNS production in phagocytes (Xenopus tropicalis)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Xenopus tropicalis)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of bile salts and organic acids, metal ions and amine compounds (Xenopus tropicalis)
Metal ion SLC transporters (Xenopus tropicalis)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Xenopus tropicalis)
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
Fe2+ [phagocytic vesicle lumen]
External Reference Information
External Reference
iron(2+) [ChEBI:29033]
Participates
as a member of
Divalent metals transported by NRAMP1 [phagocytic vesicle lumen]
This entity regulates
Positively
HOCl-induced glycosaminoglycan fragmentation
(Homo sapiens)
Other forms of this molecule
Fe2+ [cytoplasm]
Fe2+ [endoplasmic reticulum lumen]
Fe2+ [endoplasmic reticulum membrane]
Fe2+ [peroxisomal matrix]
Fe2+ [endosome lumen]
Fe2+ [extracellular region]
Fe2+ [mitochondrial inner membrane]
Fe2+ [nucleoplasm]
Fe2+ [nuclear envelope]
Fe2+ [mitochondrial intermembrane space]
Fe2+ [mitochondrial matrix]
Fe2+ [cytosol]
Cross References
AraCyc
FE+2
ChEBI
29033
COMPOUND
C14818
PubChem Compound
27284
HMDB Metabolite
HMDB0000692
KEGG Gene
C14818
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