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D-Fructose 2,6-bisphosphate [cytosol]
Stable Identifier
R-ALL-30533
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
beta-D-fructofuranose 2,6-bisphosphate, beta-D-fructofuranose 2,6-bisphosphate(4-)
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Metabolic Genes (Bos taurus)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Bos taurus)
D-Fructose 2,6-bisphosphate [cytosol]
Metabolism (Bos taurus)
Metabolism of carbohydrates and carbohydrate derivatives (Bos taurus)
Glucose metabolism (Bos taurus)
Glycolysis (Bos taurus)
PFK tetramer phosphorylates Fru(6)P (Bos taurus)
D-Fructose 2,6-bisphosphate [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Bos taurus)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Bos taurus)
D-Fructose 2,6-bisphosphate [cytosol]
PFKFKB dimer phosphorylates Fru(6)P (Bos taurus)
D-Fructose 2,6-bisphosphate [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of carbohydrates and carbohydrate derivatives (Caenorhabditis elegans)
Glucose metabolism (Caenorhabditis elegans)
Glycolysis (Caenorhabditis elegans)
PFK tetramer phosphorylates Fru(6)P (Caenorhabditis elegans)
D-Fructose 2,6-bisphosphate [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Caenorhabditis elegans)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Caenorhabditis elegans)
D-Fructose 2,6-bisphosphate [cytosol]
PFKFKB dimer phosphorylates Fru(6)P (Caenorhabditis elegans)
D-Fructose 2,6-bisphosphate [cytosol]
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional Regulation by TP53 (Canis familiaris)
TP53 Regulates Metabolic Genes (Canis familiaris)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Canis familiaris)
D-Fructose 2,6-bisphosphate [cytosol]
Metabolism (Canis familiaris)
Metabolism of carbohydrates and carbohydrate derivatives (Canis familiaris)
Glucose metabolism (Canis familiaris)
Glycolysis (Canis familiaris)
PFK tetramer phosphorylates Fru(6)P (Canis familiaris)
D-Fructose 2,6-bisphosphate [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Canis familiaris)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Canis familiaris)
D-Fructose 2,6-bisphosphate [cytosol]
PFKFKB dimer phosphorylates Fru(6)P (Canis familiaris)
D-Fructose 2,6-bisphosphate [cytosol]
Gene expression (Transcription) (Danio rerio)
RNA Polymerase II Transcription (Danio rerio)
Generic Transcription Pathway (Danio rerio)
Transcriptional Regulation by TP53 (Danio rerio)
TP53 Regulates Metabolic Genes (Danio rerio)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Danio rerio)
D-Fructose 2,6-bisphosphate [cytosol]
Metabolism (Danio rerio)
Metabolism of carbohydrates and carbohydrate derivatives (Danio rerio)
Glucose metabolism (Danio rerio)
Glycolysis (Danio rerio)
PFK tetramer phosphorylates Fru(6)P (Danio rerio)
D-Fructose 2,6-bisphosphate [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Danio rerio)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Danio rerio)
D-Fructose 2,6-bisphosphate [cytosol]
PFKFKB dimer phosphorylates Fru(6)P (Danio rerio)
D-Fructose 2,6-bisphosphate [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of carbohydrates and carbohydrate derivatives (Dictyostelium discoideum)
Glucose metabolism (Dictyostelium discoideum)
Glycolysis (Dictyostelium discoideum)
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Dictyostelium discoideum)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Dictyostelium discoideum)
D-Fructose 2,6-bisphosphate [cytosol]
PFKFKB dimer phosphorylates Fru(6)P (Dictyostelium discoideum)
D-Fructose 2,6-bisphosphate [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of carbohydrates and carbohydrate derivatives (Drosophila melanogaster)
Glucose metabolism (Drosophila melanogaster)
Glycolysis (Drosophila melanogaster)
PFK tetramer phosphorylates Fru(6)P (Drosophila melanogaster)
D-Fructose 2,6-bisphosphate [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Drosophila melanogaster)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Drosophila melanogaster)
D-Fructose 2,6-bisphosphate [cytosol]
PFKFKB dimer phosphorylates Fru(6)P (Drosophila melanogaster)
D-Fructose 2,6-bisphosphate [cytosol]
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional Regulation by TP53 (Gallus gallus)
TP53 Regulates Metabolic Genes (Gallus gallus)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Gallus gallus)
D-Fructose 2,6-bisphosphate [cytosol]
Metabolism (Gallus gallus)
Metabolism of carbohydrates and carbohydrate derivatives (Gallus gallus)
Glucose metabolism (Gallus gallus)
Glycolysis (Gallus gallus)
PFK tetramer phosphorylates Fru(6)P (Gallus gallus)
D-Fructose 2,6-bisphosphate [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Gallus gallus)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Gallus gallus)
D-Fructose 2,6-bisphosphate [cytosol]
PFKFKB dimer phosphorylates Fru(6)P (Gallus gallus)
D-Fructose 2,6-bisphosphate [cytosol]
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Metabolic Genes (Homo sapiens)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Homo sapiens)
D-Fructose 2,6-bisphosphate [cytosol]
Metabolism (Homo sapiens)
Metabolism of carbohydrates and carbohydrate derivatives (Homo sapiens)
Glucose metabolism (Homo sapiens)
Glycolysis (Homo sapiens)
PFK tetramer phosphorylates Fru(6)P (Homo sapiens)
D-Fructose 2,6-bisphosphate [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Homo sapiens)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Homo sapiens)
D-Fructose 2,6-bisphosphate [cytosol]
PFKFKB dimer phosphorylates Fru(6)P (Homo sapiens)
D-Fructose 2,6-bisphosphate [cytosol]
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
TP53 Regulates Metabolic Genes (Mus musculus)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Mus musculus)
D-Fructose 2,6-bisphosphate [cytosol]
Metabolism (Mus musculus)
Metabolism of carbohydrates and carbohydrate derivatives (Mus musculus)
Glucose metabolism (Mus musculus)
Glycolysis (Mus musculus)
PFK tetramer phosphorylates Fru(6)P (Mus musculus)
D-Fructose 2,6-bisphosphate [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Mus musculus)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Mus musculus)
D-Fructose 2,6-bisphosphate [cytosol]
PFKFKB dimer phosphorylates Fru(6)P (Mus musculus)
D-Fructose 2,6-bisphosphate [cytosol]
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
TP53 Regulates Metabolic Genes (Rattus norvegicus)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Rattus norvegicus)
D-Fructose 2,6-bisphosphate [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of carbohydrates and carbohydrate derivatives (Rattus norvegicus)
Glucose metabolism (Rattus norvegicus)
Glycolysis (Rattus norvegicus)
PFK tetramer phosphorylates Fru(6)P (Rattus norvegicus)
D-Fructose 2,6-bisphosphate [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Rattus norvegicus)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Rattus norvegicus)
D-Fructose 2,6-bisphosphate [cytosol]
PFKFKB dimer phosphorylates Fru(6)P (Rattus norvegicus)
D-Fructose 2,6-bisphosphate [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of carbohydrates and carbohydrate derivatives (Saccharomyces cerevisiae)
Glucose metabolism (Saccharomyces cerevisiae)
Glycolysis (Saccharomyces cerevisiae)
PFK tetramer phosphorylates Fru(6)P (Saccharomyces cerevisiae)
D-Fructose 2,6-bisphosphate [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Saccharomyces cerevisiae)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Saccharomyces cerevisiae)
D-Fructose 2,6-bisphosphate [cytosol]
PFKFKB dimer phosphorylates Fru(6)P (Saccharomyces cerevisiae)
D-Fructose 2,6-bisphosphate [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of carbohydrates and carbohydrate derivatives (Schizosaccharomyces pombe)
Glucose metabolism (Schizosaccharomyces pombe)
Glycolysis (Schizosaccharomyces pombe)
PFK tetramer phosphorylates Fru(6)P (Schizosaccharomyces pombe)
D-Fructose 2,6-bisphosphate [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Schizosaccharomyces pombe)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Schizosaccharomyces pombe)
D-Fructose 2,6-bisphosphate [cytosol]
PFKFKB dimer phosphorylates Fru(6)P (Schizosaccharomyces pombe)
D-Fructose 2,6-bisphosphate [cytosol]
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
TP53 Regulates Metabolic Genes (Sus scrofa)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Sus scrofa)
D-Fructose 2,6-bisphosphate [cytosol]
Metabolism (Sus scrofa)
Metabolism of carbohydrates and carbohydrate derivatives (Sus scrofa)
Glucose metabolism (Sus scrofa)
Glycolysis (Sus scrofa)
PFK tetramer phosphorylates Fru(6)P (Sus scrofa)
D-Fructose 2,6-bisphosphate [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Sus scrofa)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Sus scrofa)
D-Fructose 2,6-bisphosphate [cytosol]
PFKFKB dimer phosphorylates Fru(6)P (Sus scrofa)
D-Fructose 2,6-bisphosphate [cytosol]
Gene expression (Transcription) (Xenopus tropicalis)
RNA Polymerase II Transcription (Xenopus tropicalis)
Generic Transcription Pathway (Xenopus tropicalis)
Transcriptional Regulation by TP53 (Xenopus tropicalis)
TP53 Regulates Metabolic Genes (Xenopus tropicalis)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Xenopus tropicalis)
D-Fructose 2,6-bisphosphate [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of carbohydrates and carbohydrate derivatives (Xenopus tropicalis)
Glucose metabolism (Xenopus tropicalis)
Glycolysis (Xenopus tropicalis)
PFK tetramer phosphorylates Fru(6)P (Xenopus tropicalis)
D-Fructose 2,6-bisphosphate [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Xenopus tropicalis)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Xenopus tropicalis)
D-Fructose 2,6-bisphosphate [cytosol]
PFKFKB dimer phosphorylates Fru(6)P (Xenopus tropicalis)
D-Fructose 2,6-bisphosphate [cytosol]
External Reference Information
External Reference
beta-D-fructofuranose 2,6-bisphosphate(4-) [ChEBI:58579]
Participates
as an input of
fructose 2,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate (Gallus gallus)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Saccharomyces cerevisiae)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Schizosaccharomyces pombe)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Dictyostelium discoideum)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Caenorhabditis elegans)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Drosophila melanogaster)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Gallus gallus)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Xenopus tropicalis)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Sus scrofa)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Bos taurus)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Canis familiaris)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Rattus norvegicus)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Mus musculus)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Homo sapiens)
PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Danio rerio)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Gallus gallus)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Xenopus tropicalis)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Danio rerio)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Sus scrofa)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Bos taurus)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Canis familiaris)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Rattus norvegicus)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Mus musculus)
TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Homo sapiens)
as an output of
fructose 6-phosphate + ATP => fructose 2,6-bisphosphate + ADP (Gallus gallus)
PFKFKB dimer phosphorylates Fru(6)P (Saccharomyces cerevisiae)
PFKFKB dimer phosphorylates Fru(6)P (Schizosaccharomyces pombe)
PFKFKB dimer phosphorylates Fru(6)P (Dictyostelium discoideum)
PFKFKB dimer phosphorylates Fru(6)P (Caenorhabditis elegans)
PFKFKB dimer phosphorylates Fru(6)P (Drosophila melanogaster)
PFKFKB dimer phosphorylates Fru(6)P (Gallus gallus)
PFKFKB dimer phosphorylates Fru(6)P (Xenopus tropicalis)
PFKFKB dimer phosphorylates Fru(6)P (Sus scrofa)
PFKFKB dimer phosphorylates Fru(6)P (Bos taurus)
PFKFKB dimer phosphorylates Fru(6)P (Canis familiaris)
PFKFKB dimer phosphorylates Fru(6)P (Rattus norvegicus)
PFKFKB dimer phosphorylates Fru(6)P (Mus musculus)
PFKFKB dimer phosphorylates Fru(6)P (Homo sapiens)
PFKFKB dimer phosphorylates Fru(6)P (Danio rerio)
This entity regulates
Negatively
fructose 1,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate
(Gallus gallus)
Positively
fructose 6-phosphate + ATP => fructose 1,6-bisphosphate + ADP
(Gallus gallus)
PFKFKB dimer phosphorylates Fru(6)P
(Caenorhabditis elegans)
PFKFKB dimer phosphorylates Fru(6)P
(Drosophila melanogaster)
PFKFKB dimer phosphorylates Fru(6)P
(Canis familiaris)
PFK tetramer phosphorylates Fru(6)P
(Caenorhabditis elegans)
PFK tetramer phosphorylates Fru(6)P
(Drosophila melanogaster)
PFK tetramer phosphorylates Fru(6)P
(Canis familiaris)
PFKFKB dimer phosphorylates Fru(6)P
(Saccharomyces cerevisiae)
PFKFKB dimer phosphorylates Fru(6)P
(Dictyostelium discoideum)
PFKFKB dimer phosphorylates Fru(6)P
(Xenopus tropicalis)
PFK tetramer phosphorylates Fru(6)P
(Saccharomyces cerevisiae)
PFK tetramer phosphorylates Fru(6)P
(Xenopus tropicalis)
PFK tetramer phosphorylates Fru(6)P
(Homo sapiens)
PFKFKB dimer phosphorylates Fru(6)P
(Schizosaccharomyces pombe)
PFKFKB dimer phosphorylates Fru(6)P
(Gallus gallus)
PFKFKB dimer phosphorylates Fru(6)P
(Sus scrofa)
PFKFKB dimer phosphorylates Fru(6)P
(Bos taurus)
PFKFKB dimer phosphorylates Fru(6)P
(Rattus norvegicus)
PFKFKB dimer phosphorylates Fru(6)P
(Mus musculus)
PFKFKB dimer phosphorylates Fru(6)P
(Homo sapiens)
PFKFKB dimer phosphorylates Fru(6)P
(Danio rerio)
PFK tetramer phosphorylates Fru(6)P
(Schizosaccharomyces pombe)
PFK tetramer phosphorylates Fru(6)P
(Gallus gallus)
PFK tetramer phosphorylates Fru(6)P
(Danio rerio)
PFK tetramer phosphorylates Fru(6)P
(Sus scrofa)
PFK tetramer phosphorylates Fru(6)P
(Bos taurus)
PFK tetramer phosphorylates Fru(6)P
(Mus musculus)
PFK tetramer phosphorylates Fru(6)P
(Rattus norvegicus)
Cross References
COMPOUND
C00665
ZINC
ZINC000004228295
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