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Cu2+ [cytosol]
Stable Identifier
R-ALL-209799
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Copper, copper(2+)
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to chemical stress (Bos taurus)
Detoxification of Reactive Oxygen Species (Bos taurus)
CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Bos taurus)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Bos taurus)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Bos taurus)
Cu2+ [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Bos taurus)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Bos taurus)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Bos taurus)
Cu2+ [cytosol]
Response to metal ions (Bos taurus)
Metallothioneins bind metals (Bos taurus)
MT3 exchanges zinc for copper (Bos taurus)
Cu2+ [cytosol]
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular response to chemical stress (Caenorhabditis elegans)
Detoxification of Reactive Oxygen Species (Caenorhabditis elegans)
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Caenorhabditis elegans)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Caenorhabditis elegans)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Caenorhabditis elegans)
Cu2+ [cytosol]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to chemical stress (Canis familiaris)
Detoxification of Reactive Oxygen Species (Canis familiaris)
CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Canis familiaris)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Canis familiaris)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Canis familiaris)
Cu2+ [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Canis familiaris)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Canis familiaris)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Canis familiaris)
Cu2+ [cytosol]
Response to metal ions (Canis familiaris)
Metallothioneins bind metals (Canis familiaris)
MT3 exchanges zinc for copper (Canis familiaris)
Cu2+ [cytosol]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to chemical stress (Danio rerio)
Detoxification of Reactive Oxygen Species (Danio rerio)
CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Danio rerio)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Danio rerio)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Danio rerio)
Cu2+ [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Danio rerio)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Danio rerio)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Danio rerio)
Cu2+ [cytosol]
Response to metal ions (Danio rerio)
Metallothioneins bind metals (Danio rerio)
MT3 exchanges zinc for copper (Danio rerio)
Cu2+ [cytosol]
Cellular responses to stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Cellular response to chemical stress (Dictyostelium discoideum)
Detoxification of Reactive Oxygen Species (Dictyostelium discoideum)
CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Dictyostelium discoideum)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Dictyostelium discoideum)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Dictyostelium discoideum)
Cu2+ [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Dictyostelium discoideum)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Dictyostelium discoideum)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Dictyostelium discoideum)
Cu2+ [cytosol]
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to chemical stress (Drosophila melanogaster)
Detoxification of Reactive Oxygen Species (Drosophila melanogaster)
CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Drosophila melanogaster)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Drosophila melanogaster)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Drosophila melanogaster)
Cu2+ [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Drosophila melanogaster)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Drosophila melanogaster)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Drosophila melanogaster)
Cu2+ [cytosol]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to chemical stress (Gallus gallus)
Detoxification of Reactive Oxygen Species (Gallus gallus)
CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Gallus gallus)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Gallus gallus)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Gallus gallus)
Cu2+ [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Gallus gallus)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Gallus gallus)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Gallus gallus)
Cu2+ [cytosol]
Response to metal ions (Gallus gallus)
Metallothioneins bind metals (Gallus gallus)
MT3 exchanges zinc for copper (Gallus gallus)
Cu2+ [cytosol]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Detoxification of Reactive Oxygen Species (Homo sapiens)
CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Homo sapiens)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Homo sapiens)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Homo sapiens)
Cu2+ [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Homo sapiens)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Homo sapiens)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Homo sapiens)
Cu2+ [cytosol]
Response to metal ions (Homo sapiens)
Metallothioneins bind metals (Homo sapiens)
MT3 exchanges zinc for copper (Homo sapiens)
Cu2+ [cytosol]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Infection with Mycobacterium tuberculosis (Homo sapiens)
Latent infection - Other responses of Mtb to phagocytosis (Homo sapiens)
Tolerance of reactive oxygen produced by macrophages (Homo sapiens)
SodC reduces superoxide to H2O2 (Homo sapiens)
SodC dimer [plasma membrane] (Mycobacterium tuberculosis)
Cu2+ [cytosol]
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to chemical stress (Mus musculus)
Detoxification of Reactive Oxygen Species (Mus musculus)
CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Mus musculus)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Mus musculus)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Mus musculus)
Cu2+ [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Mus musculus)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Mus musculus)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Mus musculus)
Cu2+ [cytosol]
Response to metal ions (Mus musculus)
Metallothioneins bind metals (Mus musculus)
MT3 exchanges zinc for copper (Mus musculus)
Cu2+ [cytosol]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to chemical stress (Rattus norvegicus)
Detoxification of Reactive Oxygen Species (Rattus norvegicus)
CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Rattus norvegicus)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Rattus norvegicus)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Rattus norvegicus)
Cu2+ [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Rattus norvegicus)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Rattus norvegicus)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Rattus norvegicus)
Cu2+ [cytosol]
Response to metal ions (Rattus norvegicus)
Metallothioneins bind metals (Rattus norvegicus)
MT3 exchanges zinc for copper (Rattus norvegicus)
Cu2+ [cytosol]
Cellular responses to stimuli (Saccharomyces cerevisiae)
Cellular responses to stress (Saccharomyces cerevisiae)
Cellular response to chemical stress (Saccharomyces cerevisiae)
Detoxification of Reactive Oxygen Species (Saccharomyces cerevisiae)
CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Saccharomyces cerevisiae)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Saccharomyces cerevisiae)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Saccharomyces cerevisiae)
Cu2+ [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Saccharomyces cerevisiae)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Saccharomyces cerevisiae)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Saccharomyces cerevisiae)
Cu2+ [cytosol]
Cellular responses to stimuli (Schizosaccharomyces pombe)
Cellular responses to stress (Schizosaccharomyces pombe)
Cellular response to chemical stress (Schizosaccharomyces pombe)
Detoxification of Reactive Oxygen Species (Schizosaccharomyces pombe)
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Schizosaccharomyces pombe)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Schizosaccharomyces pombe)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Schizosaccharomyces pombe)
Cu2+ [cytosol]
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to chemical stress (Sus scrofa)
Detoxification of Reactive Oxygen Species (Sus scrofa)
CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Sus scrofa)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Sus scrofa)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Sus scrofa)
Cu2+ [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Sus scrofa)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Sus scrofa)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Sus scrofa)
Cu2+ [cytosol]
Response to metal ions (Sus scrofa)
Metallothioneins bind metals (Sus scrofa)
MT3 exchanges zinc for copper (Sus scrofa)
Cu2+ [cytosol]
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular response to chemical stress (Xenopus tropicalis)
Detoxification of Reactive Oxygen Species (Xenopus tropicalis)
CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Xenopus tropicalis)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Xenopus tropicalis)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Xenopus tropicalis)
Cu2+ [cytosol]
SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Xenopus tropicalis)
2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol] (Xenopus tropicalis)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Xenopus tropicalis)
Cu2+ [cytosol]
External Reference Information
External Reference
copper(2+) [ChEBI:29036]
Participates
as an input of
MT3 exchanges zinc for copper (Gallus gallus)
MT3 exchanges zinc for copper (Danio rerio)
MT3 exchanges zinc for copper (Sus scrofa)
MT3 exchanges zinc for copper (Bos taurus)
MT3 exchanges zinc for copper (Canis familiaris)
MT3 exchanges zinc for copper (Rattus norvegicus)
MT3 exchanges zinc for copper (Mus musculus)
MT3 exchanges zinc for copper (Homo sapiens)
as a component of
SodC dimer [plasma membrane] (Mycobacterium tuberculosis)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Sus scrofa)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Drosophila melanogaster)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Gallus gallus)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Bos taurus)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Saccharomyces cerevisiae)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Xenopus tropicalis)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Canis familiaris)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Schizosaccharomyces pombe)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Dictyostelium discoideum)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Mus musculus)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Rattus norvegicus)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Caenorhabditis elegans)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Homo sapiens)
2xHC-SOD1:Zn2+:Cu2+ [cytosol] (Danio rerio)
Other forms of this molecule
Cu2+ [melanosome membrane]
Cu2+ [Golgi lumen]
Cu2+ [extracellular region]
Cu2+ [mitochondrial intermembrane space]
Cu2+ [mitochondrial inner membrane]
Cross References
COMPOUND
C00070
HMDB Metabolite
HMDB0000657
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