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Cu2+ [mitochondrial inner membrane]
Stable Identifier
R-ALL-9864471
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial inner membrane
Synonyms
Copper, copper(2+)
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to chemical stress (Bos taurus)
Cytoprotection by HMOX1 (Bos taurus)
CO binds to Cytochrome c oxidase (Bos taurus)
Cytochrome c oxidase [mitochondrial inner membrane] (Bos taurus)
COX catalytic core [mitochondrial inner membrane] (Bos taurus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Bos taurus)
Cytochrome c oxidase [mitochondrial inner membrane] (Bos taurus)
COX catalytic core [mitochondrial inner membrane] (Bos taurus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Bos taurus)
COX catalytic core [mitochondrial inner membrane] (Bos taurus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Bos taurus)
COX catalytic core [mitochondrial inner membrane] (Bos taurus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Bos taurus)
Cytochrome c oxidase [mitochondrial inner membrane] (Bos taurus)
COX catalytic core [mitochondrial inner membrane] (Bos taurus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Metabolic Genes (Bos taurus)
Electron transfer from reduced cytochrome c to molecular oxygen (Bos taurus)
COX catalytic core [mitochondrial inner membrane] (Bos taurus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Bos taurus)
COX catalytic core [mitochondrial inner membrane] (Bos taurus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Bos taurus)
Cytochrome c oxidase [mitochondrial inner membrane] (Bos taurus)
COX catalytic core [mitochondrial inner membrane] (Bos taurus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Respiratory electron transport (Bos taurus)
Complex IV assembly (Bos taurus)
MT-CO1 and MT-CO2 complexes associate, installing heme moieties (Bos taurus)
MT-CO1:Cu2+:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Bos taurus)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:Mg2+:CuA [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
holo-MT-CO1,2 complex [mitochondrial inner membrane] (Bos taurus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex (Bos taurus)
Cytochrome c oxidase [mitochondrial inner membrane] (Bos taurus)
COX catalytic core [mitochondrial inner membrane] (Bos taurus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
holo-MT-CO1,2 complex [mitochondrial inner membrane] (Bos taurus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metallochaperone inserts 2Cu2+ into MT-CO2 (Bos taurus)
MT-CO2:Mg2+:CuA [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metallochaperone inserts Cu2+ into MT-CO1 (Bos taurus)
MT-CO1:Cu2+:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Bos taurus)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Bos taurus)
COX catalytic core [mitochondrial inner membrane] (Bos taurus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Bos taurus)
COX catalytic core [mitochondrial inner membrane] (Bos taurus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Bos taurus)
Cytochrome c oxidase [mitochondrial inner membrane] (Bos taurus)
COX catalytic core [mitochondrial inner membrane] (Bos taurus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Bos taurus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metabolism (Caenorhabditis elegans)
Aerobic respiration and respiratory electron transport (Caenorhabditis elegans)
Respiratory electron transport (Caenorhabditis elegans)
Complex IV assembly (Caenorhabditis elegans)
Metallochaperone inserts Cu2+ into MT-CO1 (Caenorhabditis elegans)
MT-CO1:Cu2+:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Caenorhabditis elegans)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Caenorhabditis elegans)
Cu2+ [mitochondrial inner membrane]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to chemical stress (Canis familiaris)
Cytoprotection by HMOX1 (Canis familiaris)
CO binds to Cytochrome c oxidase (Canis familiaris)
Cytochrome c oxidase [mitochondrial inner membrane] (Canis familiaris)
COX catalytic core [mitochondrial inner membrane] (Canis familiaris)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Canis familiaris)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Canis familiaris)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Canis familiaris)
Cytochrome c oxidase [mitochondrial inner membrane] (Canis familiaris)
COX catalytic core [mitochondrial inner membrane] (Canis familiaris)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Canis familiaris)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Canis familiaris)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Canis familiaris)
Cytochrome c oxidase [mitochondrial inner membrane] (Canis familiaris)
COX catalytic core [mitochondrial inner membrane] (Canis familiaris)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Canis familiaris)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Canis familiaris)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Canis familiaris)
Cytochrome c oxidase [mitochondrial inner membrane] (Canis familiaris)
COX catalytic core [mitochondrial inner membrane] (Canis familiaris)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Canis familiaris)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Canis familiaris)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional Regulation by TP53 (Canis familiaris)
TP53 Regulates Metabolic Genes (Canis familiaris)
Electron transfer from reduced cytochrome c to molecular oxygen (Canis familiaris)
Cytochrome c oxidase [mitochondrial inner membrane] (Canis familiaris)
COX catalytic core [mitochondrial inner membrane] (Canis familiaris)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Canis familiaris)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Canis familiaris)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Canis familiaris)
Cytochrome c oxidase [mitochondrial inner membrane] (Canis familiaris)
COX catalytic core [mitochondrial inner membrane] (Canis familiaris)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Canis familiaris)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Canis familiaris)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Respiratory electron transport (Canis familiaris)
Complex IV assembly (Canis familiaris)
Metallochaperone inserts Cu2+ into MT-CO1 (Canis familiaris)
MT-CO1:Cu2+:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Canis familiaris)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Canis familiaris)
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Canis familiaris)
Cytochrome c oxidase [mitochondrial inner membrane] (Canis familiaris)
COX catalytic core [mitochondrial inner membrane] (Canis familiaris)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Canis familiaris)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Canis familiaris)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Canis familiaris)
Cytochrome c oxidase [mitochondrial inner membrane] (Canis familiaris)
COX catalytic core [mitochondrial inner membrane] (Canis familiaris)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Canis familiaris)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Canis familiaris)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to chemical stress (Danio rerio)
Cytoprotection by HMOX1 (Danio rerio)
CO binds to Cytochrome c oxidase (Danio rerio)
Cytochrome c oxidase [mitochondrial inner membrane] (Danio rerio)
COX catalytic core [mitochondrial inner membrane] (Danio rerio)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Danio rerio)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Danio rerio)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Danio rerio)
Cytochrome c oxidase [mitochondrial inner membrane] (Danio rerio)
COX catalytic core [mitochondrial inner membrane] (Danio rerio)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Danio rerio)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Danio rerio)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Danio rerio)
COX catalytic core [mitochondrial inner membrane] (Danio rerio)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Danio rerio)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Danio rerio)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Danio rerio)
COX catalytic core [mitochondrial inner membrane] (Danio rerio)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Danio rerio)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Danio rerio)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Danio rerio)
Cytochrome c oxidase [mitochondrial inner membrane] (Danio rerio)
COX catalytic core [mitochondrial inner membrane] (Danio rerio)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Danio rerio)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Danio rerio)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Gene expression (Transcription) (Danio rerio)
RNA Polymerase II Transcription (Danio rerio)
Generic Transcription Pathway (Danio rerio)
Transcriptional Regulation by TP53 (Danio rerio)
TP53 Regulates Metabolic Genes (Danio rerio)
Electron transfer from reduced cytochrome c to molecular oxygen (Danio rerio)
COX catalytic core [mitochondrial inner membrane] (Danio rerio)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Danio rerio)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Danio rerio)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Danio rerio)
COX catalytic core [mitochondrial inner membrane] (Danio rerio)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Danio rerio)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Danio rerio)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Danio rerio)
Cytochrome c oxidase [mitochondrial inner membrane] (Danio rerio)
COX catalytic core [mitochondrial inner membrane] (Danio rerio)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Danio rerio)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Danio rerio)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Respiratory electron transport (Danio rerio)
Complex IV assembly (Danio rerio)
Metallochaperone inserts 2Cu2+ into MT-CO2 (Danio rerio)
MT-CO2:Mg2+:CuA [mitochondrial inner membrane] (Danio rerio)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Danio rerio)
COX catalytic core [mitochondrial inner membrane] (Danio rerio)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Danio rerio)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Danio rerio)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Danio rerio)
COX catalytic core [mitochondrial inner membrane] (Danio rerio)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Danio rerio)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Danio rerio)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Danio rerio)
Cytochrome c oxidase [mitochondrial inner membrane] (Danio rerio)
COX catalytic core [mitochondrial inner membrane] (Danio rerio)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Danio rerio)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Danio rerio)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to chemical stress (Drosophila melanogaster)
Cytoprotection by HMOX1 (Drosophila melanogaster)
CO binds to Cytochrome c oxidase (Drosophila melanogaster)
Cytochrome c oxidase [mitochondrial inner membrane] (Drosophila melanogaster)
COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Drosophila melanogaster)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Drosophila melanogaster)
Cytochrome c oxidase [mitochondrial inner membrane] (Drosophila melanogaster)
COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Drosophila melanogaster)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Drosophila melanogaster)
COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Drosophila melanogaster)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Drosophila melanogaster)
COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Drosophila melanogaster)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Drosophila melanogaster)
Cytochrome c oxidase [mitochondrial inner membrane] (Drosophila melanogaster)
COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Drosophila melanogaster)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Metabolic Genes (Drosophila melanogaster)
Electron transfer from reduced cytochrome c to molecular oxygen (Drosophila melanogaster)
COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Drosophila melanogaster)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Drosophila melanogaster)
COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Drosophila melanogaster)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Drosophila melanogaster)
Cytochrome c oxidase [mitochondrial inner membrane] (Drosophila melanogaster)
COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Drosophila melanogaster)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Respiratory electron transport (Drosophila melanogaster)
Complex IV assembly (Drosophila melanogaster)
MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex (Drosophila melanogaster)
Cytochrome c oxidase [mitochondrial inner membrane] (Drosophila melanogaster)
COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Drosophila melanogaster)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
holo-MT-CO1,2 complex [mitochondrial inner membrane] (Drosophila melanogaster)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Drosophila melanogaster)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metallochaperone inserts 2Cu2+ into MT-CO2 (Drosophila melanogaster)
MT-CO2:Mg2+:CuA [mitochondrial inner membrane] (Drosophila melanogaster)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metallochaperone inserts Cu2+ into MT-CO1 (Drosophila melanogaster)
MT-CO1:Cu2+:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Drosophila melanogaster)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Drosophila melanogaster)
COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Drosophila melanogaster)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Drosophila melanogaster)
COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Drosophila melanogaster)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Drosophila melanogaster)
Cytochrome c oxidase [mitochondrial inner membrane] (Drosophila melanogaster)
COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Drosophila melanogaster)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to chemical stress (Gallus gallus)
Cytoprotection by HMOX1 (Gallus gallus)
CO binds to Cytochrome c oxidase (Gallus gallus)
Cytochrome c oxidase [mitochondrial inner membrane] (Gallus gallus)
COX catalytic core [mitochondrial inner membrane] (Gallus gallus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Gallus gallus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Gallus gallus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Gallus gallus)
Cytochrome c oxidase [mitochondrial inner membrane] (Gallus gallus)
COX catalytic core [mitochondrial inner membrane] (Gallus gallus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Gallus gallus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Gallus gallus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Gallus gallus)
COX catalytic core [mitochondrial inner membrane] (Gallus gallus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Gallus gallus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Gallus gallus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Gallus gallus)
COX catalytic core [mitochondrial inner membrane] (Gallus gallus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Gallus gallus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Gallus gallus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Gallus gallus)
Cytochrome c oxidase [mitochondrial inner membrane] (Gallus gallus)
COX catalytic core [mitochondrial inner membrane] (Gallus gallus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Gallus gallus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Gallus gallus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional Regulation by TP53 (Gallus gallus)
TP53 Regulates Metabolic Genes (Gallus gallus)
Electron transfer from reduced cytochrome c to molecular oxygen (Gallus gallus)
COX catalytic core [mitochondrial inner membrane] (Gallus gallus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Gallus gallus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Gallus gallus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Gallus gallus)
COX catalytic core [mitochondrial inner membrane] (Gallus gallus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Gallus gallus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Gallus gallus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Gallus gallus)
Cytochrome c oxidase [mitochondrial inner membrane] (Gallus gallus)
COX catalytic core [mitochondrial inner membrane] (Gallus gallus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Gallus gallus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Gallus gallus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metabolism (Gallus gallus)
Aerobic respiration and respiratory electron transport (Gallus gallus)
Respiratory electron transport (Gallus gallus)
Complex IV assembly (Gallus gallus)
Metallochaperone inserts 2Cu2+ into MT-CO2 (Gallus gallus)
MT-CO2:Mg2+:CuA [mitochondrial inner membrane] (Gallus gallus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Gallus gallus)
COX catalytic core [mitochondrial inner membrane] (Gallus gallus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Gallus gallus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Gallus gallus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Gallus gallus)
COX catalytic core [mitochondrial inner membrane] (Gallus gallus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Gallus gallus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Gallus gallus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Gallus gallus)
Cytochrome c oxidase [mitochondrial inner membrane] (Gallus gallus)
COX catalytic core [mitochondrial inner membrane] (Gallus gallus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Gallus gallus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Gallus gallus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Cytoprotection by HMOX1 (Homo sapiens)
CO binds to Cytochrome c oxidase (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
COX catalytic core [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
COX catalytic core [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Homo sapiens)
COX catalytic core [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
COX catalytic core [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
COX catalytic core [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Metabolic Genes (Homo sapiens)
Electron transfer from reduced cytochrome c to molecular oxygen (Homo sapiens)
COX catalytic core [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
COX catalytic core [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
COX catalytic core [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Respiratory electron transport (Homo sapiens)
Complex IV assembly (Homo sapiens)
MT-CO1 and MT-CO2 complexes associate, installing heme moieties (Homo sapiens)
MT-CO1:Cu2+:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
MT-CO2:Mg2+:CuA [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
holo-MT-CO1,2 complex [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
COX catalytic core [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
holo-MT-CO1,2 complex [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metallochaperone inserts 2Cu2+ into MT-CO2 (Homo sapiens)
MT-CO2:Mg2+:CuA [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metallochaperone inserts Cu2+ into MT-CO1 (Homo sapiens)
MT-CO1:Cu2+:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Homo sapiens)
COX catalytic core [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
COX catalytic core [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Homo sapiens)
Cytochrome c oxidase [mitochondrial inner membrane] (Homo sapiens)
COX catalytic core [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Homo sapiens)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to chemical stress (Mus musculus)
Cytoprotection by HMOX1 (Mus musculus)
CO binds to Cytochrome c oxidase (Mus musculus)
Cytochrome c oxidase [mitochondrial inner membrane] (Mus musculus)
COX catalytic core [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Mus musculus)
Cytochrome c oxidase [mitochondrial inner membrane] (Mus musculus)
COX catalytic core [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Mus musculus)
COX catalytic core [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Mus musculus)
COX catalytic core [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Mus musculus)
Cytochrome c oxidase [mitochondrial inner membrane] (Mus musculus)
COX catalytic core [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
TP53 Regulates Metabolic Genes (Mus musculus)
Electron transfer from reduced cytochrome c to molecular oxygen (Mus musculus)
COX catalytic core [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Mus musculus)
COX catalytic core [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Mus musculus)
Cytochrome c oxidase [mitochondrial inner membrane] (Mus musculus)
COX catalytic core [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Respiratory electron transport (Mus musculus)
Complex IV assembly (Mus musculus)
MT-CO1 and MT-CO2 complexes associate, installing heme moieties (Mus musculus)
MT-CO1:Cu2+:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Mus musculus)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:Mg2+:CuA [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
holo-MT-CO1,2 complex [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex (Mus musculus)
Cytochrome c oxidase [mitochondrial inner membrane] (Mus musculus)
COX catalytic core [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
holo-MT-CO1,2 complex [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metallochaperone inserts 2Cu2+ into MT-CO2 (Mus musculus)
MT-CO2:Mg2+:CuA [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metallochaperone inserts Cu2+ into MT-CO1 (Mus musculus)
MT-CO1:Cu2+:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Mus musculus)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Mus musculus)
COX catalytic core [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Mus musculus)
COX catalytic core [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Mus musculus)
Cytochrome c oxidase [mitochondrial inner membrane] (Mus musculus)
COX catalytic core [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Mus musculus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to chemical stress (Rattus norvegicus)
Cytoprotection by HMOX1 (Rattus norvegicus)
CO binds to Cytochrome c oxidase (Rattus norvegicus)
Cytochrome c oxidase [mitochondrial inner membrane] (Rattus norvegicus)
COX catalytic core [mitochondrial inner membrane] (Rattus norvegicus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Rattus norvegicus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Rattus norvegicus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Rattus norvegicus)
Cytochrome c oxidase [mitochondrial inner membrane] (Rattus norvegicus)
COX catalytic core [mitochondrial inner membrane] (Rattus norvegicus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Rattus norvegicus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Rattus norvegicus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Rattus norvegicus)
COX catalytic core [mitochondrial inner membrane] (Rattus norvegicus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Rattus norvegicus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Rattus norvegicus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Rattus norvegicus)
COX catalytic core [mitochondrial inner membrane] (Rattus norvegicus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Rattus norvegicus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Rattus norvegicus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Rattus norvegicus)
Cytochrome c oxidase [mitochondrial inner membrane] (Rattus norvegicus)
COX catalytic core [mitochondrial inner membrane] (Rattus norvegicus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Rattus norvegicus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Rattus norvegicus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
TP53 Regulates Metabolic Genes (Rattus norvegicus)
Electron transfer from reduced cytochrome c to molecular oxygen (Rattus norvegicus)
COX catalytic core [mitochondrial inner membrane] (Rattus norvegicus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Rattus norvegicus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Rattus norvegicus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Rattus norvegicus)
COX catalytic core [mitochondrial inner membrane] (Rattus norvegicus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Rattus norvegicus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Rattus norvegicus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Rattus norvegicus)
Cytochrome c oxidase [mitochondrial inner membrane] (Rattus norvegicus)
COX catalytic core [mitochondrial inner membrane] (Rattus norvegicus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Rattus norvegicus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Rattus norvegicus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metabolism (Rattus norvegicus)
Aerobic respiration and respiratory electron transport (Rattus norvegicus)
Respiratory electron transport (Rattus norvegicus)
Complex IV assembly (Rattus norvegicus)
MT-CO1 and MT-CO2 complexes associate, installing heme moieties (Rattus norvegicus)
MT-CO1:Cu2+:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Rattus norvegicus)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Rattus norvegicus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:Mg2+:CuA [mitochondrial inner membrane] (Rattus norvegicus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
holo-MT-CO1,2 complex [mitochondrial inner membrane] (Rattus norvegicus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Rattus norvegicus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Rattus norvegicus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Rattus norvegicus)
COX catalytic core [mitochondrial inner membrane] (Rattus norvegicus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Rattus norvegicus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Rattus norvegicus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Rattus norvegicus)
COX catalytic core [mitochondrial inner membrane] (Rattus norvegicus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Rattus norvegicus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Rattus norvegicus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Rattus norvegicus)
Cytochrome c oxidase [mitochondrial inner membrane] (Rattus norvegicus)
COX catalytic core [mitochondrial inner membrane] (Rattus norvegicus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Rattus norvegicus)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Rattus norvegicus)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to chemical stress (Sus scrofa)
Cytoprotection by HMOX1 (Sus scrofa)
CO binds to Cytochrome c oxidase (Sus scrofa)
Cytochrome c oxidase [mitochondrial inner membrane] (Sus scrofa)
COX catalytic core [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Sus scrofa)
Cytochrome c oxidase [mitochondrial inner membrane] (Sus scrofa)
COX catalytic core [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Sus scrofa)
COX catalytic core [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Sus scrofa)
COX catalytic core [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Sus scrofa)
Cytochrome c oxidase [mitochondrial inner membrane] (Sus scrofa)
COX catalytic core [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
TP53 Regulates Metabolic Genes (Sus scrofa)
Electron transfer from reduced cytochrome c to molecular oxygen (Sus scrofa)
COX catalytic core [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Sus scrofa)
COX catalytic core [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Sus scrofa)
Cytochrome c oxidase [mitochondrial inner membrane] (Sus scrofa)
COX catalytic core [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Respiratory electron transport (Sus scrofa)
Complex IV assembly (Sus scrofa)
MT-CO1 and MT-CO2 complexes associate, installing heme moieties (Sus scrofa)
MT-CO1:Cu2+:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
MT-CO2:Mg2+:CuA [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
holo-MT-CO1,2 complex [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex (Sus scrofa)
Cytochrome c oxidase [mitochondrial inner membrane] (Sus scrofa)
COX catalytic core [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
holo-MT-CO1,2 complex [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metallochaperone inserts 2Cu2+ into MT-CO2 (Sus scrofa)
MT-CO2:Mg2+:CuA [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metallochaperone inserts Cu2+ into MT-CO1 (Sus scrofa)
MT-CO1:Cu2+:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Sus scrofa)
COX catalytic core [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Sus scrofa)
COX catalytic core [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Sus scrofa)
Cytochrome c oxidase [mitochondrial inner membrane] (Sus scrofa)
COX catalytic core [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Sus scrofa)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular response to chemical stress (Xenopus tropicalis)
Cytoprotection by HMOX1 (Xenopus tropicalis)
CO binds to Cytochrome c oxidase (Xenopus tropicalis)
Cytochrome c oxidase [mitochondrial inner membrane] (Xenopus tropicalis)
COX catalytic core [mitochondrial inner membrane] (Xenopus tropicalis)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Xenopus tropicalis)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Xenopus tropicalis)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Xenopus tropicalis)
Cytochrome c oxidase [mitochondrial inner membrane] (Xenopus tropicalis)
COX catalytic core [mitochondrial inner membrane] (Xenopus tropicalis)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Xenopus tropicalis)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Xenopus tropicalis)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Electron transfer from reduced cytochrome c to molecular oxygen (Xenopus tropicalis)
COX catalytic core [mitochondrial inner membrane] (Xenopus tropicalis)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Xenopus tropicalis)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Xenopus tropicalis)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Xenopus tropicalis)
COX catalytic core [mitochondrial inner membrane] (Xenopus tropicalis)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Xenopus tropicalis)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Xenopus tropicalis)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Xenopus tropicalis)
Cytochrome c oxidase [mitochondrial inner membrane] (Xenopus tropicalis)
COX catalytic core [mitochondrial inner membrane] (Xenopus tropicalis)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Xenopus tropicalis)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Xenopus tropicalis)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Gene expression (Transcription) (Xenopus tropicalis)
RNA Polymerase II Transcription (Xenopus tropicalis)
Generic Transcription Pathway (Xenopus tropicalis)
Transcriptional Regulation by TP53 (Xenopus tropicalis)
TP53 Regulates Metabolic Genes (Xenopus tropicalis)
Electron transfer from reduced cytochrome c to molecular oxygen (Xenopus tropicalis)
COX catalytic core [mitochondrial inner membrane] (Xenopus tropicalis)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Xenopus tropicalis)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Xenopus tropicalis)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Xenopus tropicalis)
COX catalytic core [mitochondrial inner membrane] (Xenopus tropicalis)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Xenopus tropicalis)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Xenopus tropicalis)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Xenopus tropicalis)
Cytochrome c oxidase [mitochondrial inner membrane] (Xenopus tropicalis)
COX catalytic core [mitochondrial inner membrane] (Xenopus tropicalis)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Xenopus tropicalis)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Xenopus tropicalis)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Metabolism (Xenopus tropicalis)
Aerobic respiration and respiratory electron transport (Xenopus tropicalis)
Respiratory electron transport (Xenopus tropicalis)
Electron transfer from reduced cytochrome c to molecular oxygen (Xenopus tropicalis)
COX catalytic core [mitochondrial inner membrane] (Xenopus tropicalis)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Xenopus tropicalis)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Xenopus tropicalis)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase [mitochondrial inner membrane] (Xenopus tropicalis)
COX catalytic core [mitochondrial inner membrane] (Xenopus tropicalis)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Xenopus tropicalis)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Xenopus tropicalis)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
Cytochrome c oxidase:CO [mitochondrial inner membrane] (Xenopus tropicalis)
Cytochrome c oxidase [mitochondrial inner membrane] (Xenopus tropicalis)
COX catalytic core [mitochondrial inner membrane] (Xenopus tropicalis)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Xenopus tropicalis)
Cu2+ [mitochondrial inner membrane]
MT-CO2:heme a:CuA:Mg2+ [mitochondrial inner membrane] (Xenopus tropicalis)
CuA [mitochondrial inner membrane]
Cu2+ [mitochondrial inner membrane]
External Reference Information
External Reference
copper(2+) [ChEBI:29036]
Participates
as a component of
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Rattus norvegicus)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Canis familiaris)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Caenorhabditis elegans)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Bos taurus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Danio rerio)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Sus scrofa)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Rattus norvegicus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Gallus gallus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Xenopus tropicalis)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Canis familiaris)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Homo sapiens)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Mus musculus)
MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
CuA [mitochondrial inner membrane]
Other forms of this molecule
Cu2+ [melanosome membrane]
Cu2+ [mitochondrial intermembrane space]
Cu2+ [Golgi lumen]
Cu2+ [cytosol]
Cu2+ [extracellular region]
Cross References
COMPOUND
C00070
HMDB Metabolite
HMDB0000657
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