Reactome | UniProt:P54790 ORC3

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UniProt:P54790 ORC3 Show undefined attributes

chain	initiator methionine:1 chain:2-616
checksum	3FAAEE3F645D3F9C
comment	FUNCTION Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication.SUBUNIT Component of the origin recognition complex (ORC) composed of at least ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. Interacts with ORC6.INTERACTION Belongs to the ORC3 family.
crossReference	[DatabaseIdentifier:12439359] RefSeq:NP_013097.1 [DatabaseIdentifier:12258121] PRO:P54790 [DatabaseIdentifier:12142006] PDB:6RQC [DatabaseIdentifier:12141991] PDB:6WGG [DatabaseIdentifier:12142002] PDB:7TJJ [DatabaseIdentifier:12142001] PDB:7TJI [DatabaseIdentifier:12141989] PDB:7MCA [DatabaseIdentifier:12141992] PDB:6WGI [DatabaseIdentifier:12141995] PDB:8ZP5 [DatabaseIdentifier:12141999] PDB:6WGC [DatabaseIdentifier:12142003] PDB:9GM5 [DatabaseIdentifier:12142000] PDB:7TJK [DatabaseIdentifier:12141997] PDB:9GJW [DatabaseIdentifier:12141990] PDB:5V8F [DatabaseIdentifier:12141996] PDB:7TJH [DatabaseIdentifier:12141987] PDB:8ZPK [DatabaseIdentifier:12142007] PDB:5ZR1 [DatabaseIdentifier:12142004] PDB:9GJP [DatabaseIdentifier:12141998] PDB:7TJF [DatabaseIdentifier:12141993] PDB:8ZP4 [DatabaseIdentifier:12141985] PDB:9BCX [DatabaseIdentifier:11739971] ENSEMBL:YLL004W_mRNA [DatabaseIdentifier:11617272] ENSEMBL:YLL004W [DatabaseIdentifier:11504939] ENSEMBL:YLL004W
databaseName	UniProt
dbId	97398
description	recommendedName: Origin recognition complex subunit 3 alternativeName: Origin recognition complex 62 kDa subunit
displayName	UniProt:P54790 ORC3
geneName	ORC3 OAF1 OIF1 YLL004W L1365
identifier	P54790
isSequenceChanged	false
keyword	3D-structure Acetylation Direct protein sequencing DNA replication DNA-binding Nucleus Reference proteome
modified	[InstanceEdit:9963647] Weiser, Joel, 2025-08-15
moleculeType	Protein
name	ORC3
otherIdentifier	850656 GO:0003674 GO:0003677 GO:0003682 GO:0003688 GO:0005515 GO:0005575 GO:0005634 GO:0005654 GO:0005656 GO:0005664 GO:0006260 GO:0006267 GO:0006270 GO:0006325 GO:0008150 GO:0030466 GO:0031261
physicalEntity	[EntityWithAccessionedSequence:R-SCE-9749325] yORC3 [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-68513] ORC3 [nucleoplasm] - Saccharomyces cerevisiae
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12759798] UCSC:P54790 ORC3 [ReferenceDNASequence:12084352] NCBI Gene:850656 ORC3 [ReferenceDNASequence:12000259] Monarch:850656 ORC3 [ReferenceDNASequence:11908596] KEGG:sce:YLL004W ORC3 [ReferenceDNASequence:11370470] BioGPS Gene:850656 ORC3
referenceTranscript	[ReferenceRNASequence:12620870] RefSeq:NM_001181824.1 ORC3
schemaClass	ReferenceGeneProduct
secondaryIdentifier	ORC3_YEAST D6VXZ9
sequenceLength	616
species	[Species:68322] Saccharomyces cerevisiae
stId	uniprot:P54790
url	http://purl.uniprot.org/uniprot/P54790

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