Reactome | phospho-foxo4 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-XTR-9614653] p-T32,S197,S262-FOXO4:YWHAZ dimer [cytosol] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-9614564] 14-3-3 proteins bind AKT-phosphorylated FOXO4 - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10721261
displayName	phospho-foxo4 [cytosol]
endCoordinate	505
hasModifiedResidue	[ModifiedResidue:10665098] O-phospho-L-serine at 197 (in Homo sapiens) [ModifiedResidue:10665099] O-phospho-L-serine at 262 (in Homo sapiens) [ModifiedResidue:10665100] O-phospho-L-threonine at 32 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-9614415] p-T32,S197,S262-FOXO4 [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-XTR-9614416] p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4 [cytosol] - Xenopus tropicalis
name	phospho-foxo4 p-T32,S197,S262-FOXO4 F6RTU2
referenceEntity	[ReferenceGeneProduct:uniprot:F6RTU2] UniProt:F6RTU2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9614415
startCoordinate	1

(input)	[Reaction:R-XTR-9614564] 14-3-3 proteins bind AKT-phosphorylated FOXO4
(hasComponent)	[Complex:R-XTR-9614653] p-T32,S197,S262-FOXO4:YWHAZ dimer [cytosol]
(hasMember)	[DefinedSet:R-XTR-9614416] p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4 [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-9614415] p-T32,S197,S262-FOXO4 [cytosol]

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