Reactome | phospho-foxo3 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-XTR-9614628] p-T32,S253,S315-FOXO3:YWHAZ,YWHAQ,SFN [cytosol] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-9614562] 14-3-3 proteins bind AKT-phosphorylated FOXO3 - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10721259
displayName	phospho-foxo3 [cytosol]
endCoordinate	673
hasModifiedResidue	[ModifiedResidue:10665093] O-phospho-L-serine at 253 (in Homo sapiens) [ModifiedResidue:10665094] O-phospho-L-serine at 315 (in Homo sapiens) [ModifiedResidue:10665095] O-phospho-L-threonine at 32 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-9614413] p-T32,S253,S315-FOXO3 [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-XTR-9614416] p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4 [cytosol] - Xenopus tropicalis
name	phospho-foxo3 p-T32,S253,S315-FOXO3 F7DZ24
producedByEvent	[BlackBoxEvent:R-XTR-9699581] AKT-phosphorylated FOXO3 translocates to cytosol - Xenopus tropicalis [BlackBoxEvent:R-XTR-9624527] AKT-phosphorylated FOXO3 translocates to cytosol - Xenopus tropicalis
referenceEntity	[ReferenceGeneProduct:uniprot:F7DZ24] UniProt:F7DZ24
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9614413
startCoordinate	2

(output)	[BlackBoxEvent:R-XTR-9699581] AKT-phosphorylated FOXO3 translocates to cytosol [BlackBoxEvent:R-XTR-9624527] AKT-phosphorylated FOXO3 translocates to cytosol
(input)	[Reaction:R-XTR-9614562] 14-3-3 proteins bind AKT-phosphorylated FOXO3
(hasMember)	[DefinedSet:R-XTR-9614416] p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4 [cytosol]
(hasComponent)	[Complex:R-XTR-9614628] p-T32,S253,S315-FOXO3:YWHAZ,YWHAQ,SFN [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-9614413] p-T32,S253,S315-FOXO3 [cytosol]

Cite Us!