Reactome | RHOQ GEFs activate RHOQ

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RHOQ GEFs activate RHOQ Show undefined attributes

catalystActivity	[CatalystActivity:10720062] guanyl-nucleotide exchange factor activity of RHOQ GEFs [cytosol]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10720064
displayName	RHOQ GEFs activate RHOQ
eventOf	[Pathway:R-XTR-9013406] RHOQ GTPase cycle - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-9018746] RHOQ binds effectors at the plasma membrane - Xenopus tropicalis [Reaction:R-XTR-9018745] RHOQ GAPs stimulate RHOQ GTPase activity - Xenopus tropicalis [BlackBoxEvent:R-XTR-9018836] RHOQ translocates to the Golgi-associated vesicle membranes - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-9018747] RHOQ GEFs activate RHOQ - Homo sapiens
input	[SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-XTR-9018839] RHOQ:GDP [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	RHOQ GEFs activate RHOQ
output	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-XTR-2316453] RHOQ:GTP [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9018747
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-9013406] RHOQ GTPase cycle
(precedingEvent)	[Reaction:R-XTR-9018746] RHOQ binds effectors at the plasma membrane [Reaction:R-XTR-9018745] RHOQ GAPs stimulate RHOQ GTPase activity [BlackBoxEvent:R-XTR-9018836] RHOQ translocates to the Golgi-associated vesicle membranes
(inferredTo)	[Reaction:R-HSA-9018747] RHOQ GEFs activate RHOQ