Reactome | Interleukin-15 signaling

Schema > Pathway > Entries

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10731216
displayName	Interleukin-15 signaling
eventOf	[Pathway:R-XTR-451927] Interleukin-2 family signaling - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:1301068] interleukin-15-mediated signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[BlackBoxEvent:R-XTR-8983373] p-Y-STAT3 binds p-STAT5 - Xenopus tropicalis [BlackBoxEvent:R-XTR-8983379] p-Y-STAT3:p-STAT5 translocates to the nucleus - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-8983432] Interleukin-15 signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Interleukin-15 signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-8983432
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-451927] Interleukin-2 family signaling
(inferredTo)	[Pathway:R-HSA-8983432] Interleukin-15 signaling

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