Reactome | CDK4,CDK6:CCND [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-XTR-8942622] CDK4/6:CCND:p-Y77-CDKN1A,p-Y88-CDKN1B,(p-Y91-CDKN1C) [cytosol] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-8941915] Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10716706
displayName	CDK4,CDK6:CCND [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-XTR-68328] ccnd1 [cytosol] [DefinedSet:R-XTR-69209] CDK4,CDK6 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8941896] CDK4,CDK6:CCND [cytosol] - Homo sapiens
maxDepth	3
name	CDK4,CDK6:CCND
producedByEvent	[Reaction:R-XTR-8941895] Formation of CDK4/6:CCND complexes - Xenopus tropicalis
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-8941896
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-XTR-8942622] CDK4/6:CCND:p-Y77-CDKN1A,p-Y88-CDKN1B,(p-Y91-CDKN1C) [cytosol] [Complex:R-XTR-8941921] CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [cytosol] [Complex:R-XTR-8949871] CDK4,CDK6:CCND:p-Y88-CDKN1B [cytosol]
(input)	[Reaction:R-XTR-8941915] Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes
(output)	[Reaction:R-XTR-8941895] Formation of CDK4/6:CCND complexes
(inferredTo)	[Complex:R-HSA-8941896] CDK4,CDK6:CCND [cytosol]