Reactome | cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]

Schema > Reaction > Entries

cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] Show undefined attributes

catalystActivity	[CatalystActivity:10654560] nucleoside kinase activity of UCK1 tetramer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10654562
displayName	cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]
eventOf	[Pathway:R-XTR-73614] Pyrimidine salvage - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-73548] (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-73599] cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [DefinedSet:R-ALL-500759] Cyt-Rib, Ura-Rib [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] cytidine + ATP => CMP + ADP + H(+) uridine + ATP => UMP + ADP + H(+)
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [DefinedSet:R-ALL-500761] CMP, UMP [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-73599
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-XTR-73548] (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1)
(hasEvent)	[Pathway:R-XTR-73614] Pyrimidine salvage
(inferredTo)	[Reaction:R-HSA-73599] cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]

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