Reactome | Formation of the ternary complex, and subsequently, the 43S complex

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Formation of the ternary complex, and subsequently, the 43S complex Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10728578
displayName	Formation of the ternary complex, and subsequently, the 43S complex
eventOf	[Pathway:R-XTR-72737] Cap-dependent Translation Initiation - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-XTR-72663] De novo formation of eIF2:GTP - Xenopus tropicalis [Reaction:R-XTR-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Xenopus tropicalis [Reaction:R-XTR-72691] Formation of the 43S pre-initiation complex - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-72695] Formation of the ternary complex, and subsequently, the 43S complex - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Formation of the ternary complex, and subsequently, the 43S complex
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-72695
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-72737] Cap-dependent Translation Initiation
(inferredTo)	[Pathway:R-HSA-72695] Formation of the ternary complex, and subsequently, the 43S complex

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