Reactome | CDC6 association with the ORC:origin complex

Schema > Pathway > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10728368
displayName	CDC6 association with the ORC:origin complex
eventOf	[Pathway:R-XTR-68867] Assembly of the pre-replicative complex - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-XTR-9749215] MCM8 binds CDC6 - Xenopus tropicalis [Reaction:R-XTR-68688] CDC6 association with ORC(1-6) at replication origins - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-68689] CDC6 association with the ORC:origin complex - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	CDC6 association with the ORC:origin complex
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-68689
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-68867] Assembly of the pre-replicative complex
(inferredTo)	[Pathway:R-HSA-68689] CDC6 association with the ORC:origin complex

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