Reactome | MET receptor dimerizes

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10710288
displayName	MET receptor dimerizes
eventOf	[Pathway:R-XTR-6806942] MET Receptor Activation - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-6806974] MET dimers autophosphorylate - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-6806957] MET receptor dimerizes - Homo sapiens
input	2 × [Complex:R-XTR-6800287] HGF dimer:MET [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	MET receptor dimerizes
output	[Complex:R-XTR-6806956] HGF:MET dimer [plasma membrane]
precedingEvent	[Reaction:R-XTR-6800298] HGF dimer binds MET - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-6806957
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-6806942] MET Receptor Activation
(precedingEvent)	[Reaction:R-XTR-6806974] MET dimers autophosphorylate
(inferredTo)	[Reaction:R-HSA-6806957] MET receptor dimerizes

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